A5013294043- Catalytic Processes in Materials Science
- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Meat and Animal Product Quality
- Hybrid Renewable Energy Systems
- Catalysis and Oxidation Reactions
- Electrocatalysts for Energy Conversion
- Tissue Engineering and Regenerative Medicine
- Hydrogen Storage and Materials
- Epoxy Resin Curing Processes
- Wound Healing and Treatments
- Crystallization and Solubility Studies
- Proteins in Food Systems
- Ammonia Synthesis and Nitrogen Reduction
- X-ray Diffraction in Crystallography
- Metal-Organic Frameworks: Synthesis and Applications
- Mechanical Behavior of Composites
- Advanced oxidation water treatment
- Fiber-reinforced polymer composites
- 3D Printing in Biomedical Research
- Luminescence and Fluorescent Materials
- Microencapsulation and Drying Processes
- Environmental remediation with nanomaterials
- Graphene research and applications
- Melanoma and MAPK Pathways
China University of Petroleum, East China
2013-2025
Chongqing University of Technology
2023-2025
Guizhou Provincial People's Hospital
2022-2025
Sun Yat-sen University
2022-2025
Sun Yat-sen University Cancer Center
2022-2025
Songho University
2024
Hanalei Watershed Hui
2024
Guizhou University
2024
Shandong Academy of Sciences
2017-2023
Qilu University of Technology
2017-2023
Abstract Cutaneous wound healing, especially diabetic is a common clinical challenge. Reactive oxygen species (ROS) and bacterial infection are two major detrimental states that induce oxidative stress inflammatory responses impede angiogenesis healing. A derivative of the metabolite itaconate, 4‐octyl itaconate (4OI) has attracted increasing research interest in recent years due to its antioxidant anti‐inflammatory properties. In this study, 4OI‐modified black phosphorus (BP) nanosheets...
Repairing infected bone defects is a challenge in the field of orthopedics because limited self-healing capacity tissue and susceptibility refractory materials to bacterial activity. Innervation initiating factor for regeneration plays key regulatory role subsequent vascularization, ossification, mineralization processes. Infection leads necrosis local nerve fibers, impeding repair defects. Herein, biomaterial that can induce skeletal-associated neural network reconstruction with high...
In this study, scallop mantle protein was treated by ultrasound at different powers, and then analyzed ANS fluorescent probes, circular dichroism spectroscopy, endogenous fluorescence spectrum, DNTB colorimetry in-vitro digestion model to elucidate the structure-function relationship. The results indicated that can significantly affect secondary structure of like enhancing hydrophobicity, lowering particle size, increasing relative contents α-helix decreasing β-pleated sheet, β-turn random...
In situ tissue engineering is a powerful strategy for the treatment of bone defects. It could overcome limitations traditional engineering, which typically involves extensive cell expansion steps, low survival rates upon transplantation, and risk immuno-rejection. Here, porous scaffold polycaprolactone (PCL)/decellularized small intestine submucosa (SIS) was fabricated via cryogenic free-form extrusion, followed by surface modification with aptamer PlGF-2123-144*-fused BMP2 (pBMP2). The two...
The management of diabetic wounds faces significant challenges due to the excessive activation reactive oxygen species (ROS), dysregulation inflammatory response, and impaired angiogenesis. A substantial body evidence suggests that aforementioned diverse factors contributing delayed healing may be associated with autophagy. Impaired autophagy leads endothelial fibroblast dysfunction impedes macrophage phenotypic transformation. This disruption hinders angiogenesis extracellular matrix...
Abstract Pyroptosis is a form of programmed cell death (PCD) that plays vital role in immunity and diseases. Although it was recently reported chemotherapy drugs can induce pyroptosis through caspase‐3‐dependent cleavage gasdermin E (GSDME), the osteosarcoma (OS) with dioscin less understood. In this study, we explored effects on OS vitro vivo further elucidated underlying molecular mechanisms found dioscin‐triggered GSDME‐dependent GSDME‐N generated by caspase‐3. Furthermore, inhibited...
Chemoresistance is the main obstacle of treatment in patients with osteosarcoma. RNA-binding protein PTBP1 has been identified as an oncogene various cancers. However, role osteosarcoma, especially chemoresistant and underlying mechanism remain unclear. In this study, we aimed to explore functions chemoresistance We found that was significantly increased chemotherapeutically insensitive osteosarcoma tissues cisplatin-resistant cell lines (MG-63CISR U-2OSCISR ) compared chemotherapy-sensitive...
Abstract To treat bone defects, repairing the nerve‐rich periosteum is critical for local electric field. In this study, an endogenous field coupled with 2D black phosphorus electroactive to explore its role in promoting regeneration through nerves. Scanning electron microscopy (SEM) and transmission (TEM) are used characterize electrically active biomimetic periosteum. Here, vitro effects exerted by on transformation of Schwann cells into repair phenotype, axon initial segment (AIS) dense...
Self-consistent periodic density functional theory (PW91-GGA) calculations are employed to study the oxidation of methanol on PtRu(111). Geometries and energies for all intermediates involved analyzed, network is mapped out illustrate reaction mechanism. On PtRu(111), Ru atoms with less electronegativity more favorable binding adsorbates than Pt atoms. Alloying weakens bond CO Pt, but strengthens Ru. All possible pathways through initial C–H, O–H, C–O scissions considered. The O–H scission...
Abstract Long noncoding RNAs (lncRNAs) were identified as a vital part in the development and progression of cancer recent years. Colorectal neoplasia differentially expressed (CRNDE), lncRNA, functions an oncogene some malignant neoplasias, but its role osteosarcoma (OS) is still poorly understood. To dissect difference expression CRNDE, quantitative real‐time polymerase chain reaction was utilized to evaluate it OS tissues cell lines (U2OS, MG63, MNNG/HOS) compared with that adjacent...
The effect of high hydrostatic pressure (HHP) (0.1, 100, 200, 300, 400 and 500 MPa) on the structure–emulsifying relationship scallop mantle protein was investigated. Overall, HHP could significantly change secondary structure including decrease α-helix relative content increase β-fold content, surface hydrophobicity, free sulfhydryl groups protein. Compared with untreated ones, had small particle size, zeta potential, solubility, interfacial tension, as well good emulsifying properties...
Abstract Anti‐PD‐1 immunotherapy and targeted therapy (TT) represent two major therapeutic modalities for BRAF V600 ‐mutant advanced melanoma, but the efficacy of combination in Asian populations remains unknown. melanoma patients differ significantly from Caucasians tissue subtypes, pathogenesis response to treatment. We retrospectively analyzed data treated with first‐line vemurafenib (V) ± anti‐PD‐1 or dabrafenib+trametinib (D+T) between 2014 2023 three centers China. 178 were included, V...
<title>Abstract</title> Dibenzyltoluene (DBT) is one of the most promising hydrogen storage media liquid organic carriers (LOHCs), but it difficult to solve problems low catalyst selectivity and deactivation caused by high by-products dehydrogenation. This study designed Pt<sub>2.0</sub>Cu<sub>0.1</sub>/Al<sub>2</sub>O<sub>3</sub>-900 ℃ that could balance activity, stability dehydrogenation perhydrodibenzyltoluene (18H-DBT). method involved appropriate acid pretreatment Pt-Cu synergistic...
Alumina support Pt catalyst with highly dispersed Cu shows synergistic effect for dehydrogenation of 12H-MBT.
Organic polymers possessing excited‐state intramolecular proton transfer (ESIPT) significantly impact their electronic and optical properties through stimulus response, leading to unique photoluminescence behaviors such as large Stokes shifts, dual emission, environmental sensitivity. In this work, polyimides (PIs) exhibiting both ESIPT room‐temperature phosphorescence (RTP) were designed synthesized by end‐capping with 5‐amino‐2‐(2‐hydroxyphenyl) benzothiazole (HBTA) benzimidazole (HBIA),...
Background Sarcopenia (SP) and Intervertebral Disc Degeneration (IVDD) are common age-related diseases that significantly affect the physical mental health of patients. A substantial body evidence suggests a potential association between SP IVDD. However, causal relationship IVDD remains uncertain. Objectives This study aimed to determine whether is by employing Mendelian randomization (MR) analysis. Methods Genome-wide (GWAS) data related (measured muscle lean mass, left- right-hand grip...
The utilization of myofibrillar proteins (MPs) from the scallop mantle was limited due to its poor digestibility in vitro . In this study, structural properties and MP were evaluated after modified by ultra-high pressure (UHP) at different pressures (0.1, 100, 200, 300, 400, 500 MPa). results showed that high could significantly increase ordered structure content like α-helix, inhibit formation disulfide bonds, decrease surface hydrophobicity. Moreover, possessed optimal solubility 200 MPa...
Boiling is an effective way to enhance the shellfish flavor. Headspace-Gas Chromatography-Ion Mobility Spectrum (HS-GC-IMS) coupled with multivariate analyses was applied illustrate effect of boiling on volatile organic compounds (VOCs) Ruditapes philippinarum. Quantitative descriptive analysis (QDA) evaluate aroma profile philippinarum during boiling. The correlation between VOCs and properties also built through partial least-squares regression (PLSR) model. In this study, flavor...
A combination of grand canonical Monte Carlo (GCMC) and density functional theory (DFT) simulations was used to investigate the effect modified metal center in ligand for CO2 capture novel Zr-based porphyrinic metal–organic frameworks (PCN-224-Ms, M = Mg, Fe, Co, Ni, Mn, Zr). The results show that MTCPP ligands (TCPP tetrakis(4-carboxyphenyl)porphyrin) provide more favorable adsorption sites than inorganic Zr6 nodes molecules. modification has a remarkable on single-component compared CH4...