A5049267735- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Bladder and Urothelial Cancer Treatments
- Intraocular Surgery and Lenses
- Anesthesia and Pain Management
- Urinary Bladder and Prostate Research
- Anesthesia and Neurotoxicity Research
- Immunotherapy and Immune Responses
- Cell Adhesion Molecules Research
- Cancer-related molecular mechanisms research
- Sexual function and dysfunction studies
- Genital Health and Disease
- Radiomics and Machine Learning in Medical Imaging
- Spine and Intervertebral Disc Pathology
- Epigenetics and DNA Methylation
- Erythrocyte Function and Pathophysiology
- Autopsy Techniques and Outcomes
- Nutrition, Genetics, and Disease
- MRI in cancer diagnosis
- Esophageal Cancer Research and Treatment
- Pediatric Urology and Nephrology Studies
- Methemoglobinemia and Tumor Lysis Syndrome
- Ubiquitin and proteasome pathways
- Inflammatory Biomarkers in Disease Prognosis
Yangzhou University
2016-2025
Northern Jiangsu People's Hospital
2017-2025
Taihe Hospital
2018
The University of Texas MD Anderson Cancer Center
2011-2017
81th Hospital of PLA
2015
Southern Medical University
2014
Chaozhou Central Hospital
2014
The detection of CTCs prior to and during therapy is an independent strong prognostic marker, it predictive poor treatment outcome. A major challenge that different technologies are available for isolation characterization in peripheral blood (PB). We compare the CellSearch system AdnaTest BreastCancer Select/Detect, evaluate extent these assays differ their ability detect PB MBC patients. 7.5 ml were isolated enumerated using CellSearch, before new treatment. Two cutoff values ≥2 ≥5...
To assess the impact of biopsy core length on discrepancy in Gleason score between and radical prostatectomy specimens. Retrospective analysis clinical data from 247 patients who underwent transperineal prostate cancer at our centre 2022 to 2023. The included age, pre-biopsy prostate-specific antigen (PSA) levels, volume, number needles, positive length, post-radical score. Statistics were analysed by SPSS26. On histopathological examination, no changes observed 127 (51.4%) patients, whereas...
Previous studies have shown that increased levels of chemokine receptor CXCR7 are associated with the invasiveness prostate cancer cells. We now show expression is upregulated in VCaP and C4-2B cells after enzalutamide (ENZ) treatment. ENZ treatment induced apoptosis (sub-G1) cells, this effect was further combination CCX771, a specific inhibitor. The p-EGFR (Y1068), p-AKT (T308) VEGFR2 were reduced CCX771 compared to single agent In addition, significantly greater reductions migration those...
Marital status is an independent prognostic factor for survival in several types of cancer, but has not been fully studied prostate cancer (PCa). A total 95,846 men diagnosed with PCa were treated radical prostatectomy (RP) between 2004 and 2009 within 18 Surveillance, Epidemiology End Results registries. Survival curves generated using Kaplan-Meier estimates differences assessed the log-rank test. Cox regression models used to assess impact marital on outcomes. The results demonstrated that...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is highly prevalent in southern China. The aim of this study to assess the extent disease Chinese neonates and determine its molecular characteristics using a novel screening method.A total 2500 were routinely screened for G6PD modified fluorescent spot test (FST). PCR-high-resolution melting (HRM) analysis was then used assay.The overall incidence 2.68% our cohort. Frequency male population 3.22% (44 1365 neonates), female 2.03% (23 1135...
To evaluate the predictive value of neutrophil-to-lymphocyte ratio (NLR) in diagnosis prostate cancer (PCa). Data 662 patients who underwent biopsy from January 2012 to June 2016 were retrospectively reviewed. The receiver operating characteristic–derived area under curve analyses performed assess accuracy. Simultaneously, Youden's index was calculated determine optimal NLR cutoff. Furthermore, univariate and multivariate logistic regression association between PCa detection. On account an...
Objective: The objective of this study was to evaluate the anesthetic efficacy periprostatic nerve block (PNB) in transrectal ultrasound (TRUS)-guided biopsy on different prostate volume. Methods: A total 568 patients received our hospital from May 2013 September 2015 and were retrospectively studied. All divided into local anesthesia group (LAG) (NBG). Then each subdivided 4 subgroups (20–40, 40–60, 60–100, >100 mL groups) according volume range. Visual analogue scale (VAS) visual numeric...
Our study aims to evaluate the anesthetic efficacy of multiparametric magnetic resonance imaging/transrectal ultrasound (mpMRI/TRUS) fusion-guided targeted periprostatic nerve block (PNB) for transperineal template-guided prostate biopsy (TTPB).The patients who underwent mpMRI/TRUS from May 2018 March 2019 were randomized into two groups using a random number table. The intervention group (n=47) and control (n=45) received PNB traditional PNB, respectively. Visual analog scale (VAS) visual...
To evaluate the efficacy of pelvic plexus block (PPB) in relief pain during transperineal template-guided prostate biopsy (TTPB), compared with conventional periprostatic nerve (PNB).From July 2016 to August 2017, 245 patients who were performed TTPB Clinical Medical College Yangzhou University recruited. The randomized into three groups using a random number table. Group-1 received capsule local anesthesia 22 ml 1% lidocaine. Group-2 additionally PNB on basis Group-1. perform PNB, 5...
Objective: To assess the complications of transperineal template-guided prostate mapping biopsy (TTMB). Methods: Between May 2017 and March 2018, 142 consecutive patients with prior negative transrectal results persistently elevated prostate-specific antigen (PSA) were divided into observation group control randomly. The underwent TTMB saturation (TTSB). Bleeding, infection, urinary function recorded after biopsy. Erectile (ED) was measured at baseline, 1 month, 3 months 6 using...
<b><i>Background:</i></b> The aim of this study was to evaluate the clinical value 16 G biopsy needle in transperineal template-guided prostate (TTPB), compared with 18 needle. <b><i>Methods:</i></b> patients who underwent TTPB from August 2020 February 2021 were randomized into 2 groups using a random number table. control group (<i>n</i> = 65) and observation 58) performed (Bard MC l820) l616) needles, respectively. Positive rate...
Objective To evaluate the clinical significance of permanent 125 I prostate brachytherapy in patients with castration‐resistant cancer. Methods A retrospective study 45 cancer from Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu, China was carried out. Patients were divided into two groups according to different treatments: 21 received endocrine therapy alone (control group), and 24 underwent combined (treatment group). Prostate‐specific antigen progression‐free survival,...
Background and Objectives: To compare the oncological functional outcomes of brachytherapy (BT) radical prostatectomy (RP) in patients with localized prostate cancer (PCa). Materials Methods: We retrospectively analyzed data from 557 PCa who were treated BT (n = 245) or RP 312) at Northern Jiangsu People's Hospital between January 2012 December 2017. Biochemical relapse-free survival (bRFS) cancer-specific (CSS) compared by treatment modality. Multivariate Cox regression analysis was used to...
ABSTRACT Objectives To explore the diagnostic value of dual‐energy computed tomography (DECT) in patients with gouty arthritis. Methods A total 160 arthritis who were treated our hospital from January 2023 to October selected as research subjects. The participants randomly divided into two groups: an observation group and a control group. Each had 80 cases. Observation performed DECT examination X‐ray examination. researchers recorded general information both groups conducted single‐factor...
Abstract: A novel human leucocyte antigen‐A (HLA‐A) allele, A*2451, has been identified during routine sequence‐specific oligonucleotide typing and sequence‐based of a sample from registered donor the Chinese Marrow Donor Program. The A*2451 allele differs closest matching A*2415 by one nucleotide substitution in exon 3, nt 363 G→A, resulting an amino acid change M ATG to I ATA at codon 121.
Objective: To explore the correlation between prostate imaging report and data system (PI-RADS) score international society of uological pathology (ISUP) grade cancer (PCa) role PI-RADS in predicting pathological features clinically significant PCa (csPCa), positive surgical margin upgrade. Methods: The pathologically patients with multi-parameter magnetic resonance image (mpMRI) were included this study. specific antigen (PSA)<100 μg/L divided into two groups: biopsy group (n=523) RP...
In patients with multiparameter magnetic resonance imaging (mpMRI) low-possibility but highly clinical suspicion of prostate cancer, the biopsy core is unclear. Our study aims to introduce density (BD; ratio cores volume) and investigates BD-predictive value cancer clinically significant (csPCa) in PI-RADS<3 patients.Patients underwent transperineal template-guided from 2012 2022. The inclusion criteria were a positive digital rectal examination or persistent PSA abnormalities. BD was...
Background and Objectives: To evaluate the efficacy of bladder-prostatic muscle reconstruction bladder neck eversion anastomosis in recovery urinary continence after robot-assisted radical prostatectomy (RARP). Materials Methods: From January 2020 to May 2022, 69 patients who underwent RARP our hospital were recruited. Thirty-seven with Veil Aphrodite technique (control group). On basis control group, 32 during (observation The was followed up at 24 h 1, 4, 12, weeks catheter removal....
You have accessJournal of UrologyProstate Cancer: Basic Research III1 Apr 2015MP55-19 SUPPRESSION OF AUTOPHAGY BY CHLOROQUINE POTENTIATES THE ANTI-CANCER EFFECT DOCETAXEL ON CASTRATION-RESISTANT PROSTATE CANCER CELLS Wen Song, Jun Yang, Yang Cai, Luan, Li Wu, Xia Liu, Tao Wang, Shao Ji and Zhang Ye SongWen Song More articles by this author , YangJun CaiYang Cai LuanYang Luan WuLi Wu LiuXia Liu WangTao Wang WangShao LiuJi YeZhang View All Author...
Objective To investigate the influence factors of periprostatic nerve block(PNB) anaesthesia. Methods A total 375 patients who underwent prostate biopsy under PNB were analyzed retrospectively from July 2014 to February 2018. It was evaluated correlation anesthetic efficacy with age, volume, PSA, body mass index, spouse, degree education, occupation, diabetes history, operation time, number cores and clinical stage. A visual analog scale (VAS) used assess pain patients. Univariate...