Lancelot Marique

ORCID: 0000-0002-6910-4364
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About
Contact & Profiles
Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Pancreatitis Pathology and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Gallbladder and Bile Duct Disorders
  • Esophageal and GI Pathology
  • Organ Transplantation Techniques and Outcomes
  • Gastric Cancer Management and Outcomes
  • Caveolin-1 and cellular processes
  • Liver Disease and Transplantation
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Erythrocyte Function and Pathophysiology
  • Sarcoma Diagnosis and Treatment
  • Bariatric Surgery and Outcomes
  • Ophthalmology and Eye Disorders
  • Liver Disease Diagnosis and Treatment
  • Gastrointestinal Tumor Research and Treatment
  • Thyroid Disorders and Treatments
  • Abdominal Trauma and Injuries
  • Glaucoma and retinal disorders
  • Cardiac tumors and thrombi
  • Minimally Invasive Surgical Techniques
  • Organ Donation and Transplantation
  • Congenital Diaphragmatic Hernia Studies
  • Central Venous Catheters and Hemodialysis
  • Biliary and Gastrointestinal Fistulas

Cliniques Universitaires Saint-Luc
2015-2024

UCLouvain
2015-2024

Hôpital Beaujon
2022-2024

Assistance Publique – Hôpitaux de Paris
2022-2024

Université Paris Cité
2022-2024

Hashimoto's thyroiditis (HT) and Graves' disease (GD) are thyroid autoimmune disorders driven by Th1 Th2 immune responses, respectively. Caveolin-1 (Cav-1), peroxidase (TPO), dual oxidase (DUOX) thought to be part of the thyroxisome, which is essential maintain hormone synthesis, at apical membrane. To analyze thyroxisome in HT GD thyroids, we investigated Cav-1, DUOX, TPO expression as well markers oxidative stress (OS), cell proliferation, apoptosis, antioxidant defenses. The effects...

10.1210/jc.2013-3469 article EN The Journal of Clinical Endocrinology & Metabolism 2014-01-29

The Resection And Partial Liver Transplantation with Delayed total hepatectomy (RAPID) procedure involves left orthotopic implantation of a lobe and right portal vein ligation. This technique induces volumetric graft increase, allowing for completion within 15 days. Notably, there is lack data on the hemodynamics small-for-size grafts exposed to overflow without triggering syndrome.

10.1097/sla.0000000000006475 article EN Annals of Surgery 2024-08-07

Graves' orbitopathy (GO) is the main extrathyroidal manifestation associated with disease (GD). It characterized by reduced eye motility due to an increased volume of orbital fat and/or extraocular muscles (EOMs) infiltrated fibrosis and adipose tissue. The pathogenetic mechanisms leading adipogenesis are mainly based on interaction between fibroblasts immune cells (lymphocytes mast cells) infiltrating GO EOMs.Analysis morphological status, oxidative stress (OS), antioxidant defenses in...

10.1089/thy.2015.0087 article EN Thyroid 2015-07-15

Peroxisome proliferator-activated receptor γ (PPARγ) is a transcription factor that regulates the expression of multiple target genes involved in several metabolic pathways as well inflammation. The and cell localization caveolin-1 (Cav-1), thyroperoxidase (TPO), dual oxidase (DUOX), extracellular iodination, modulated by Th1 cytokines human normal thyroid cells Hashimoto's thyroiditis (HT).The objectives this study were (i) to analyze PPARγ protein mRNA at follicular level HT versus...

10.1089/thy.2015.0625 article EN Thyroid 2016-06-20

Background: Even though the clinical features of Graves' orbitopathy (GO) are well known, its exact pathogenesis remains controversial. The imbalance redox homeostasis in connective tissue could play a crucial role leading to an inflammatory state and edema soft orbital tissues, thus contributing hypoxia increase hypoxia-inducible factor (HIF)-1α. This oxidative stress appears target cells such as fibroblasts also adipocytes. study aims explore which pathways can lead aforementioned GO...

10.1089/thy.2020.0238 article EN Thyroid 2020-09-26

Herniation of the liver through anterior abdominal wall is an extremely rare phenomenon. Most cases occur within incisional hernia (mostly upper abdomen surgery or cardiac surgery). Only two reports mentioned herniation without previous incision. Case Presentation. We report case a 70-year-old woman presenting epigastric swelling. Radiological findings showed in primary ventral hernia. This first to have been described requiring semiurgent repair associated with partial resection.This is,...

10.1155/2021/6698361 article EN cc-by Case Reports in Surgery 2021-05-31

10.11604/pamj.2024.47.48.42594 article IT cc-by Pan African Medical Journal 2024-01-01

Abstract Text We report 3 cases of misdeployment type II during an EDGI procedure, successfully treated with endoscopic salvage techniques. During the creation gastrogastrostomy fistula a direct technique over guide wire, distal flange migrated out excluded stomach into peritoneal cavity. The "Remove and Replace" was used in one patient "LAMS LAMS" other two. Endoscopic therapy performed all cases. appears to be easier than technique, by reducing number exchanges risk losing access...

10.1055/s-0044-1783237 article EN Endoscopy 2024-04-01
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