A5104883257- Viral Infections and Immunology Research
- Viral gastroenteritis research and epidemiology
- Cytomegalovirus and herpesvirus research
- Monoclonal and Polyclonal Antibodies Research
- Celiac Disease Research and Management
- Carbohydrate Chemistry and Synthesis
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Pandemic Impacts
- Hepatitis Viruses Studies and Epidemiology
- Glycosylation and Glycoproteins Research
National Center of Infectious and Parasitic Diseases
2005-2015
Centre for Advanced Study
2005
Abstract We sought datasets with granular age distributions of rotavirus-positive disease presentations among children <5 years age, before the introduction rotavirus vaccines. identified 117 and fit parametric to each country dataset mortality stratum. calculated median cumulative proportion gastroenteritis events expected occur at ages between birth 5.0 years. The hospital admissions was 38 weeks (interquartile range [IQR], 25–58 weeks) in countries very high child 65 (IQR, 40–107 low...
An aseptic meningitis outbreak emerged in two regions Bulgaria 2012 and echovirus 30 (E30) was established as the aetiological agent by cell culture isolation, serological test, molecular-based techniques. A total of 157 patients with were investigated, which 117 confirmed having E30-associated disease. Molecular analysis 12 E30 isolates revealed 99-100% nucleotide amino-acid identity between them a close correlation Greek strain involved an 2012. Children aged 5-14 years mainly affected,...
Abstract Oral poliovirus vaccine (OPV) can cause, in extremely rare cases vaccine‐associated paralytic poliomyelitis recipients, or contacts of vaccinees. Three (two and one recipient) occurred the Bourgas region Bulgaria spring 2006. The first two cases, notified as acute flaccid paralysis, were 55 days old unvaccinated twin brothers, having been contact with third case concerned a 4‐month‐old infant who had received OPV dose 37 prior to onset illness. Complete clinical, epidemiological,...
In the beginning of February 2007, a marked increase in number cases acute gastroenteritis Samokov, region western Bulgaria, south capital Sofia, was noted by Regional Inspectorate for Public Health Protection and Control.
Sialyltransferases (ST) are a family of enzymes specifically transporting sialic acids (SAs) onto nascent glycoproteins and glycolipids, so participating in glycoprotein synthesis. The envelope human immunodeficiency virus—type 1 (HIV-1) is highly glycosylated sialylated. Here we report for the first time data on ST-activity acutely chronically HIV-1 infected cells cell culture. results demonstrated higher ST activity cytosols both compared to uninfected ones. Data fit well our earlier...
The results of virological investigations patients with a suspect enterovirus etiology diseases conducted in the National Reference Enterovirus Laboratory during period 2001–2004 are presented. epidemic outbreak Poliomyelitis observed March-May 2001 is given special place report. Three cases wild polio type 1 virus-associated were registered then. Wild virus was isolated from two and healthy children. Its North Indian origin proved by genetic analysis isolates carried out CDC-Atlanta....