A5075655109- Animal Virus Infections Studies
- Microbial infections and disease research
- Influenza Virus Research Studies
- Cytokine Signaling Pathways and Interactions
- interferon and immune responses
- Animal Disease Management and Epidemiology
- Reproductive tract infections research
- Amoebic Infections and Treatments
- Parasites and Host Interactions
- Virus-based gene therapy research
- Parasitic Infections and Diagnostics
- Reproductive Physiology in Livestock
- Genetic factors in colorectal cancer
- Milk Quality and Mastitis in Dairy Cows
- COVID-19 Impact on Reproduction
- Mycobacterium research and diagnosis
- Gut microbiota and health
- Research on Leishmaniasis Studies
- Veterinary medicine and infectious diseases
- Virology and Viral Diseases
- Respiratory viral infections research
- Mosquito-borne diseases and control
- Calpain Protease Function and Regulation
- Bacteriophages and microbial interactions
- Viral Infections and Vectors
University of Saskatchewan
2016-2017
Université de Tours
2012-2016
InterDigital (Canada)
2016
Vancouver Infectious Diseases Centre
2016
Infectiologie Animale et Santé Publique
2011-2015
Outcomes of Zika virus (ZIKV) infection in pregnant women vary from the birth asymptomatic offspring to abnormal development and severe brain lesions fetuses infants. There are concerns that affected utero born without apparent symptoms may develop mental illnesses. Therefore, animal models important test interventions against health sequelae symptomatic likely more widespread offspring. To partially reproduce humans, we directly inoculated selected porcine conceptuses with ZIKV. Inoculation...
Viral respiratory diseases remain of major importance in swine breeding units. Swine influenza virus (SIV) is one the main known contributors to infectious diseases. The innate immune response viruses has been assessed many previous studies. However most these studies were carried out a single-cell population or directly live animal, all its complexity. In current study we report use trachea epithelial cell line (newborn pig cells – NPTr) comparison with alveolar macrophages and lung slices...
The domestic pig is an excellent animal model to study human microbial diseases due its similarity humans in terms of anatomy, physiology, and genetics. We assessed the suitability vitro air-liquid interface (ALI) culture system for newborn trachea (NPTr) cells as a practical tool analyzing immune response respiratory epithelial aggressors. This cell line offers wide susceptibility spectrum both viruses bacteria. purpose our was evaluate characterize diverse aspects differentiation using...
In pigs, influenza A viruses and Mycoplasma hyopneumoniae (Mhp) are major contributors to the porcine respiratory disease complex. Pre-infection with Mhp was previously shown experimentally exacerbate clinical outcomes of H1N1 infection during first week after virus inoculation. order better understand interactions between these pathogens, we aimed assess very early responses (at 5, 24 48 h) in pigs pre-infected or not Mhp. Clinical signs macroscopic lung lesions were similar both infected...
Chlamydiaceae is a family of intracellular bacteria causing range diverse pathological outcomes. The most devastating human diseases are ocular infections with C. trachomatis leading to blindness and genital pelvic inflammatory disease long-term sequelae including infertility chronic pain. In order enable the comparison experiments between laboratories investigating host-chlamydia interactions, infectious titer has be determined. Titer determination chlamydia commonly performed via...
Entamoeba histolytica is an important parasite of the human intestine. Its life cycle monoxenous with two stages: (i) trophozoite, growing in intestine and (ii) cyst corresponding to dissemination stage. The trophozoite can live as a commensal leading asymptomatic infection or tissue invasive form producing mucosal ulcers liver abscesses. There no animal model mimicking whole disease cycle. Most biological information on E. has been obtained from adapted axenic culture. reproduction...