- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Congenital Heart Disease Studies
- Infective Endocarditis Diagnosis and Management
- Infectious Aortic and Vascular Conditions
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac pacing and defibrillation studies
- Venous Thromboembolism Diagnosis and Management
- Tracheal and airway disorders
- Advanced Adaptive Filtering Techniques
- Congenital Diaphragmatic Hernia Studies
- Cardiac Arrhythmias and Treatments
- Intestinal and Peritoneal Adhesions
- Atrial Fibrillation Management and Outcomes
- Vasculitis and related conditions
- Non-Invasive Vital Sign Monitoring
- Fuel Cells and Related Materials
- Coronary Artery Anomalies
- Viral Infections and Immunology Research
- Soft Robotics and Applications
Tokyo Medical and Dental University
2015-2024
Osaka University
2011-2024
Toneyama National Hospital
2024
Tokyo Medical and Dental University Hospital
2020
University of Electro-Communications
2017
National Cerebral and Cardiovascular Center
2011
The University of Tokyo
2011
Shanghai Institute of Ceramics
2011
Kanazawa University
2007
Boston Children's Hospital
1996
The aim of the present study was to review clinical profile and outcome emergency surgery for complicated acute type B aortic dissection.A total 34 consecutive patients requiring surgical treatment dissection between 2003 2010 were examined. median age 64.0 years (range, 19-82 years). Indication rupture in 11 patients, rapid expansion dissecting aorta 5, involving a non-dissecting aneurysm 6, organ malperfusion 12. All 3 with open died during surgery. Operative mortality 9.7% (central...
Abstract We have evaluated the feasibility of a newly developed single‐use, magnetically levitated centrifugal blood pump, M ed T ech ag‐ L ev, in 3‐week extracorporeal membrane oxygenation ( ECMO ) study calves against edtronic B io‐ P ump BPX ‐80. A heparin‐ and silicone‐coated polypropylene oxygenator MERA NHP E xcelung NSH ‐ R was employed as an oxygenator. Six healthy male H olstein with body weights about 100 kg were divided into two groups, four group group. Under general anesthesia,...
Veno-venous extracorporeal membrane oxygenation (VV ECMO) is an effective and proven adjunct support for various severe respiratory failures requiring invasive mechanical ventilation cardiovascular support. In response to the rapidly increasing number of COVID-19 patients in Japan, we launched ECMO team comprised multidisciplinary experts including physicians, nurses, perfusionists, bioethicists preparation threat a pandemic. From April 2 July 15, 2020, Tokyo Medical Dental University...
After restrictive mitral annuloplasty (RMAP) for functional regurgitation (MR), the MR frequently recurs. Papillary muscle relocation (PMR) should reduce recurrence rate. We assessed influence of procedural differences in PMR on postoperative valve configuration. Thirty-nine patients who underwent repair were enrolled. In limited tethering cases, RMAP alone was performed (RMAP group; n = 23). severe addition to RMAP, bilateral papillary muscles relocated direction posterior annulus...
* BACKGROUND AND OBJECTIVE: To determine the intraoperative stress on surgeons and assistants during cataract surgery, 12 3 assisting nurses were assessed based their level of professional experience. METHODS: Surgeons classified as inexperienced, intermediate, or experienced. Nurse inexperienced The heart rates urine adrenaline levels each participant measured. RESULTS: Inexperienced nurse had highest at beginning tended to decrease toward end surgery. All values higher than other two...
Abstract OBJECTIVES There are few reports on the rotational position of aortic valve relative to base left ventricle, and its influence valve-sparing root replacement (VSRR) has not been reported. Based our experience with complications such as right atrial perforation tricuspid injury, we investigated cause these in terms morphological variations surrounding structures. METHODS The rotation ventricle was assessed 30 patients tri-leaflet valves who underwent VSRR. anatomical surgical...
Abstract Complications due to pump thrombus remain the weak point of mechanical circulatory support (MCS), such as use a left ventricular assist device (LVAD) or extracorporeal membrane oxygenation, leading poor outcomes. Hyperspectral imaging (HSI) is an effective method using hyperspectral (HS) camera, which comprises spectrophotometer and charge‐coupled camera discriminate from whole blood. Animal experiments were conducted analyze dynamic inside prototype hydrodynamically levitated...
We developed an optical thrombus sensor for a monopivot extracorporeal centrifugal blood pump. In this study, we investigated its quantitative performance detection in acute animal experiments of left ventricular assist using the pump on pathogen-free pigs. Optical fibers were set driver unit The incident light at near-infrared wavelength 810 nm was aimed pivot bearing, and resulting scattered guided to fibers. detected signal analyzed obtain formation level. As result, real-time monitoring...
Abstract Understanding the thrombus formation in cardiovascular devices such as rotary blood pumps is most important issue developing more hemocompatible devices. The objective of this study was to develop a hyperspectral imaging ( HSI ) method visualize growth process within pump and investigate optical properties thrombus. An vitro thrombogenic test conducted using fresh porcine specially designed hydrodynamically levitated centrifugal with transparent bottom. rotating at 3000 rpm...
Some patients with coronavirus disease 2019 (COVID-19) develop pneumothorax. Tube thoracotomy and bulla resection could generate aerosols cause virus transmission; the optimal treatment strategy remains unclear.A 57-year-old male was transferred as a severe COVID-19 pneumonia case. On 16th day after admission, patient's respiratory condition deteriorated, chest X-ray revealed presence of right-sided A drain immediately inserted; however, significant air leak continued, ventilator settings...
The goal of this study was to evaluate the outcomes patients with subvalvular procedures for functional tricuspid regurgitation (TR) severe leaflet tethering.Of 175 who had valve surgery between June 2016 and 2021, a total 17 TR preoperative tethering height ≥8 mm underwent (annular repositioning [An-Rep]) reduce septal tethering, papillary muscle relocation anterior and/or bundling [PMB] posterior along ring annuloplasty at our institution. A single procedure performed in 9 (An-Rep 5...
We have been using the flanged composite aortic prosthesis and Carrel button technique to re-attach coronary ostia in root replacement procedures at our institution over last twenty five years. Our objective was evaluate long-term results of with this technique.A total 73 patients from January 1984 August 2010 were included study. The median age 52.7 ± 14.4 years (range 28-80 years). There 48 male 25 female patients. 44 (60.3%) had annuloaortic ectasia, 15 (20.5%) acute type A dissection....
A 73-year-old woman presented with sinoatrial block.Transthoracic echocardiography revealed a tumor-like mass (2.5 cm × 3.0 cm) located in the mitral annulus (Fig. 1(A)).Caseous calcification of was suspected, which supported by computed tomography (CT) and magnetic resonance imaging (MRI) 1 (B-D)).Mitral valve replacement performed using 25-mm Mosaic Ultra bioprosthesis 2 (A andB)).
We developed a hyperspectral imaging (HSI) method to image rotary blood pump rotating at high speed, and we investigated the optical properties of associated with clotting. In vitro antithrombogenic testing was conducted. Fresh porcine circulated by hydrodynamically levitated centrifugal while light pulsed same frequency as rotational speed illuminated bottom surface pump. Back scattering captured an HSI camera, spectral in wavelength range from 608 752 nm constructed. area suspected...
This study aimed to evaluate the outcomes of patients who underwent restrictive annuloplasty (RA) plus papillary muscle relocation anteriorly (PMR-A) with risk factors in mitral valve repair for functional regurgitation (FMR).Eighty-six RA FMR. Thirty-five them received additional bilateral severe leaflet tethering. The muscles were relocated posteriorly (PMR-P) early study. Then, later period, technique was modified PMR-A, which 24 cases. survival undergoing + PMR-A examined...
Short- to mid-term extracorporeal ventricular assist devices (VADs) are recommended for critical cardiogenic shock patients. We have designed a preclinical, single-use MedTech Mag-Lev VAD one-month use. The impeller-rotor of the pump was suspended by two degree-of-freedom active magnetic bearing in 300 μm fluid gap, where computational dynamics analysis predicted secondary flow about 400–500 ml/min at speed 1800–2200 rpm. Three eddy current sensors were employed implement noise- and...
Abstract Continuous optical monitoring of thrombus formation in extracorporeal mechanical circulatory support (EMCS) devices will contribute to safe, long‐term EMCS. A clinically applicable detector must be able distinguish among the characteristics oxygen saturation (SaO 2 ), hematocrit (Hct), and formation. In vitro studies spectral changes at wavelengths from 400 900 nm associated with SaO , Hct, formed around top pivot bearing a Gyro C1E3 pump were conducted. Fresh porcine blood...
78歳男性.4年前より右鼠径部膨隆・陰嚢腫大を自覚するも放置していた.陰嚢腫大が進行し,歩行障害を主訴に当院を受診した.来院時,陰嚢底部が右大腿中点まで達していた.CTにて回盲部腸管を内容物とする右鼠径ヘルニアと診断した.また,虫垂は先端に糞石を有し,炎症性に腫大していた.右総腸骨動脈瘤(最大径45mm)の合併も認めた.二期手術を行うこととし,まず鼠径部アプローチにて虫垂切除とヘルニア根治術(メッシュプラグ法)を施行した.ヘルニア内容物は約150cmの回腸と盲腸であり,腸管に虚血性変化や癒着は認めなかった.術後経過に問題はなく,動脈瘤の変化も認めなかった.3カ月後に右総腸骨動脈瘤に対してYグラフト置換術を施行した.ヘルニア手術時より1年経った現在も,ヘルニア再発はなく,メッシュプラグや人工血管の感染といった合併症も認めていない.