A5032012769- Plant Molecular Biology Research
- Plant Reproductive Biology
- Wastewater Treatment and Nitrogen Removal
- Chromosomal and Genetic Variations
- Cancer Immunotherapy and Biomarkers
- Hematopoietic Stem Cell Transplantation
- Plant Stress Responses and Tolerance
- Genomics and Phylogenetic Studies
- Renal and related cancers
- Microbial Community Ecology and Physiology
- Soil Carbon and Nitrogen Dynamics
- Acute Lymphoblastic Leukemia research
- Constructed Wetlands for Wastewater Treatment
- Plant Virus Research Studies
- Microbial Fuel Cells and Bioremediation
- Marine and coastal ecosystems
- Prenatal Screening and Diagnostics
- Photosynthetic Processes and Mechanisms
- Soil and Water Nutrient Dynamics
- Fire effects on ecosystems
- Cancer, Stress, Anesthesia, and Immune Response
- Plant tissue culture and regeneration
- Genetic Mapping and Diversity in Plants and Animals
- Cytokine Signaling Pathways and Interactions
- Cardiac Imaging and Diagnostics
China Agricultural University
2016-2025
Hangzhou Medical College
2025
Zhejiang Provincial People's Hospital
2025
Ningbo University of Technology
2024
Ruijin Hospital
2024
Shanghai Jiao Tong University
2022-2024
Feminist Archive North
2024
Chinese Academy of Agricultural Sciences
2022-2024
Rice Research Institute
2024
China National Rice Research Institute
2024
GRAS transcription factors usually act as integrators of multiple growth regulatory and environmental signals, including axillary shoot meristem formation, root radial pattering, phytohormones, light signaling, abiotic/biotic stress. However, little is known about this gene family in tomato (Solanum lycopersicum), the most important model plant for crop species with fleshy fruits. In study, 53 genes were identified renamed based on whole-genome sequence their respective chromosome...
Abstract A complete telomere-to-telomere (T2T) finished genome has been the long pursuit of genomic research. Through generating deep coverage ultralong Oxford Nanopore Technology (ONT) and PacBio HiFi reads, we report here a assembly maize with each chromosome entirely traversed in single contig. The 2,178.6 Mb T2T Mo17 base accuracy over 99.99% unveiled structural features all repetitive regions genome. There were several super-long simple-sequence-repeat arrays having consecutive...
In Arabidopsis, the miR171-GRAS module has been clarified as key player in meristem maintenance. However, knowledge about its role fruit crops like tomato (Solanum lycopersicum) remains scarce. We previously identified SlGRAS24 a target gene of Sly-miR171. To study this probable transcription factor, we generated transgenic plants underexpressing SlGRAS24, overexpressing Sly-miR171 and expressing β-glucuronidase (GUS) under promoter (proSlGRAS24-GUS). Plants (SlGRAS24-OE) had pleiotropic...
Flue-cured tobacco production in China is typically over-fertilised and mono-cropped. To understand how this agronomic management affects soil structure organic matter, study investigated the effect of rotation, fertilizer rate, manure amendment on proportion water stable aggregates aggregate-associated carbon (SOC) total nitrogen (TSN) concentrations stocks production. Two systems (Tobacco monoculture Tobacco-rice rotation) with four treatments (0, 75, 112 kg N/ha, 60 N/ha + manure) were...
Abiotic stresses are major environmental factors that inhibit plant growth and development impacting crop productivity. GRAS transcription play critical diverse roles in abiotic stress. In this study, SlGRAS40, a member of the tomato (Solanum lycopersicum) family, was functionally characterized. wild-type (WT) tomato, SlGRAS40 upregulated by stress induced treatment with D-mannitol, NaCl, or H2O2. Transgenic plants overexpressing (SlGRAS40-OE) were more tolerant drought salt than WT....
VEGF binding to VEGFR2 leads endocytosis and downstream signaling activation promote angiogenesis. Methods: Using genetic strategies, we tested the requirement of α subunits heterotrimeric G proteins (Gαi1/3) in process. Results: Gαi1/3 are located complex (VEGFR2-Ephrin-B2-Dab2-PAR-3), where they required for transduction. knockdown, knockout or dominant negative mutation inhibited VEGF-induced endocytosis, Akt-mTOR Erk-MAPK activation. Functional studies show that shRNA proliferation,...
Abstract Kiwifruit is an economically and nutritionally important fruit crop with extremely high contents of vitamin C. However, the previously released versions kiwifruit genomes all have a mass unanchored or missing regions. Here, we report highly continuous completely gap-free reference genome Actinidia chinensis cv. ‘Hongyang’, named Hongyang v4.0, which first to achieve two de novo haploid-resolved haplotypes, HY4P HY4A. HY4A total length 606.1 599.6 Mb, respectively, almost entire...
The dispensable maize (Zea mays L.) B chromosome is highly heterochromatic and widely believed to be devoid of functional genes. Although low-copy causes no obvious phenotype variation, its existence might influence A genome gene expression. Previous studies suggested that chromosomes are evolved from standard chromosomes; therefore, they contain genic regions showing homology with sequences. Our data influences the A-genome transcription stronger effect associated an increase in copy number...
This study aimed to explore the anti-tumor effect of icaritin loading poly (lactic-co-glycolic acid) nanoparticles (refer PLGA@Icaritin NPs) on gastric cancer (GC) cells. Transmission Electron Microscope (TEM), size distribution, zeta potential, drug-loading capability, and other physicochemical characteristics NPs were carried out. Furthermore, flow cytometry, confocal laser scanning microscope (CLSM), Cell Counting Kit-8 (CCK-8), Transwell, Elisa assay Balb/c mice applied cellular uptake,...
In Arabidopsis thaliana, ARGONAUTE1 (AGO1) interacts with miR168 to modulate the small RNA regulatory pathway. However, underlying mechanism of regulation and relationship between AGO1 is poorly understood in cash crop Solanum lycopersicum (tomato). We previously found that SlAGO1A SlAGO1B were cleaved by tomato. this study, we show accumulate miR168-sponge transgenic plants, expression miR168-resistant (4m-SlAGO1A) (4m-SlAGO1B) tomato results a series defects affecting growth rate, floral...
CRISPR/Cas9-induced genome editing is a powerful tool for studying gene function in variety of organisms, including plants. Using multi-sgRNAs to target one or more genes helpful improve the efficacy and facilitate multi-gene editing. Here, we describe CRISPR/Cas9 system which can be conveniently developed as CRISPR kit. SgRNA expression cassettes rapidly generated by one-step PCR using our In kit, there are two binary vectors pHNCas9 pHNCas9HT. The vector was constructed allow assemble up...
Abstract High temperatures interfere with meiotic recombination and the subsequent progression of meiosis in plants, but few genes involved thermotolerance have been characterized. Here, we characterize a maize (Zea mays) classic dominant male-sterile mutant Ms42, which has defects pairing synapsis homologous chromosomes DNA double-strand break (DSB) repair. Ms42 encodes member heat shock protein family, HSP101, accumulates pollen mother cells. Analysis hsp101 null mutants reveals that...
The escalation of urbanization correlates with rising rates inflammatory bowel disease (IBD), necessitating research into new etiological factors. This study aims to elucidate the gut microbiota profiles in IBD patients and compare them healthy controls a western city China. We conducted multicenter case-control from end 2020, using 16S rRNA gene sequencing (n = 36) metagenomic 12) analyze newly diagnosed patients, including those Crohn's (CD) ulcerative colitis (UC). Our results...