A5100448694- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Meningioma and schwannoma management
- Peripheral Nerve Disorders
- Vascular Procedures and Complications
- Aortic aneurysm repair treatments
- Ferroptosis and cancer prognosis
- Venous Thromboembolism Diagnosis and Management
- Atherosclerosis and Cardiovascular Diseases
- Diagnosis and Treatment of Venous Diseases
- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Job Satisfaction and Organizational Behavior
- Methemoglobinemia and Tumor Lysis Syndrome
- Sirtuins and Resveratrol in Medicine
- Pesticide Exposure and Toxicity
- Water Treatment and Disinfection
- Natural product bioactivities and synthesis
- Renal and Vascular Pathologies
- Reconstructive Surgery and Microvascular Techniques
- Neurological Disease Mechanisms and Treatments
- Creativity in Education and Neuroscience
- Neuroinflammation and Neurodegeneration Mechanisms
- Anesthesia and Pain Management
Nanchang University
2018-2024
Guangxi University of Science and Technology
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2006-2024
Peking Union Medical College Hospital
2006-2024
First Affiliated Hospital of Jiangxi Medical College
2024
Hangzhou Xixi hospital
2024
Zhejiang University
2024
Ministry of Agriculture and Rural Affairs
2023
Chinese Academy of Fishery Sciences
2023
Center for Drug Evaluation and Research
2021
Purpose: The purpose of our study is to explore how employees respond illegitimate tasks and the impact it will have on employee creativity, as well important boundary conditions for weakening negative enhancing its positive impact. Methods: We collected 271 pairs employee-supervisor valid matching data through three rounds surveys, conducted statistical analysis hypothesis testing using SPSS 26.0 AMOS 24.0 tools. Results: results show that both job crafting work withdrawal play a mediating...
Purpose: Resveratrol has been shown to enhance the survival of retinal ganglion cells (RGCs) following ischemia-reperfusion (I/R) injury for glaucoma. However, precise mechanisms resveratrol's protective effects are still unclear. The aim this study is determine whether resveratrol can inhibit RGC apoptosis, gliosis, and inflammation, all which critical events in degeneration I/R injury. Methods: Right ischemia was induced adult male Sprague Dawley rats by increasing intraocular pressure 110...
Abstract A private testing laboratory reported in a Citizen Petition (CP) to FDA that 16 of 38 metformin drug products they tested had N -nitrosodimethyl amine (NDMA) amounts above the allowable intake (AI) 96 ng/day. Because been monitoring drugs for nitrosamines, orthogonal analytical procedures developed, validated and applied detect following nitrosamines (if present): (i) NDMA (with dedicated method) or (ii) second confirmatory method), -nitroso-diethylamine (NDEA), -ethyl-...
Surface rupture of carotid plaque can cause severe cerebrovascular disease, including transient ischemic attack and stroke. The aim this study was to elucidate the molecular mechanism governing progression provide candidate treatment targets for atherosclerosis.The microarray dataset GSE28829 RNA-seq GSE104140, which contain advanced early samples, were utilized in our analysis. Differentially expressed genes (DEGs) screened using "limma" R package. Gene modules both plaques identified based...
<h3>Importance</h3> A publication reported that<i>N</i>-nitrosodimethylamine (NDMA), a probable human carcinogen, was formed when ranitidine and nitrite were added to simulated gastric fluid. However, the concentrations used greater than range detected in acidic fluid prior clinical studies. <h3>Objective</h3> To characterize NDMA formation following addition of using combinations volume, pH levels, concentrations, including physiologic levels. <h3>Design, Setting, Participants</h3> One...
Purpose: Renal artery aneurysm (RAA) is a rare disease. This study proposed and evaluated new classification for RAA to assist in surgical decision-making. Materials Methods: Single-center data of 105 patients with RAAs from the vascular department surgery were collected retrospectively. A scheme was proposed. Type I aneurysms arise main trunk, accessory branch, or first-order branches away any bifurcation. II first bifurcation narrow necks (defined as dome-to-neck ratio >2) intralobular...
The retrospective cohort study was conducted to estimate the opioid-sparing anesthesia and limited side-effects with ultrasound (US)-guided ESPB using programmed intermittent bolus (PIB) or continuous infusion (CI) standard opioid-based in patients undergoing video-assisted thoracoscopic lobectomy (VATS).Patients underwent VATS were stratified into either control group one of two groups a 1:2:2 ratio depending on whether PIB implemented not. primary endpoint intra- post-operative opioids...
BACKGROUND:Many patients are not responsive or tolerant to medical therapies for carotid atherosclerosis. Thus, elucidating the molecular mechanism pathogenesis and progression of atherosclerosis identifying new potential targets that can slow prevent ischemic events quite important. MATERIAL AND METHODS:We downloaded expression profiling data PBMC in Biobank Karolinska Endarterectomy (BiKE, GSE21545) GEO. The WGCNA DEG screening were conducted. co-expression pattern between with (the group)...
Rupture of intracranial aneurysm (IA) is the leading cause subarachnoid hemorrhage. However, there are few pharmacological therapies available for prevention IA rupture. Therefore, exploring molecular mechanisms which underlie rupture and identifying potential targets preventing vital importance.We used Gene Expression Omnibus (GEO) datasets GSE13353, GSE15629, GSE54083 in our study. The 3 were merged normalized. Differentially expressed gene (DEG) screening weighted correlation network...
The present study aims to investigate the protective effects of Resveratrol (RSV) against vascular endothelial damage caused by lower-extremity I/R and underlying preliminary mechanism. in vitro hypoxia reoxygenation (HR) model was established on HUVECs. Lower-extremity rats followed being treated with RSV pathological state artery evaluated HE EVG staining, while apoptotic detected TUNEL assay. cell viability MTT assay cells determined Hoechst test flow cytometry DCFH-DA staining used...
Percutaneous transluminal angioplasty and stenting (PTA + stent) has gained acceptance as a primary treatment modality for the superficial femoral artery (SFA) diseases. Popliteal embolization (PAE) is severe complication in SFA interventions. The purpose of this study was to evaluate incidence, risk factors, prognosis PAE PTA stent.Chronic arteriosclerosis cases that underwent stent were reviewed from retrospectively maintained database. Runoff vessels evaluated all before after...
Current research is mostly focused on the impact of fertilizers human health when they are ingested through food; main form this chronic damage. Intoxication oral ingestion fertilizer an extremely rare situation. We report a case 38-year-old man that attempted to commit suicide by ingesting only 20 mL water-soluble fertilizer. Acute kidney injury occurred early, which showed toxicity could not be ignored. It was necessary seek medical attention as soon possible. In addition, patient...
To evaluate the potential efficacy of Triptolide (TP) on cerebral ischemia/reperfusion injury (CIRI) and to uncover underlying mechanism through which TP regulates CIRI. We constructed a middle artery occlusion/reperfusion (MCAO/R) mouse model simulate CIRI, established lipopolysaccharide (LPS)-stimulated BV-2 cell mimic inflammatory state during The neurological deficits score (NS) mice were measured for assessment neurologic functions. Both severity infarction apoptosis level in brain...