- Video Surveillance and Tracking Methods
- Advanced Sensor and Energy Harvesting Materials
- Advanced Neural Network Applications
- Lipid metabolism and disorders
- Polymer Surface Interaction Studies
- Conducting polymers and applications
- Molecular Junctions and Nanostructures
- Advanced biosensing and bioanalysis techniques
- Tactile and Sensory Interactions
- Nanoplatforms for cancer theranostics
- EEG and Brain-Computer Interfaces
- Hydraulic Fracturing and Reservoir Analysis
- Hydrocarbon exploration and reservoir analysis
- Neural dynamics and brain function
- Enhanced Oil Recovery Techniques
- Histone Deacetylase Inhibitors Research
- Autonomous Vehicle Technology and Safety
- Peptidase Inhibition and Analysis
- Nanoparticle-Based Drug Delivery
- Advanced Image and Video Retrieval Techniques
- Biosensors and Analytical Detection
- Functional Brain Connectivity Studies
- Liver Disease Diagnosis and Treatment
- Extracellular vesicles in disease
- Chemokine receptors and signaling
Fudan University
2021-2025
Minhang District Central Hospital
2024
Wuhan University
2021-2023
Jilin University
2023
Xiamen University
2023
Dalian University of Technology
2014-2019
Dalian University
2014-2019
East China University of Science and Technology
2018
State Key Laboratory of Fine Chemicals
2015
We demonstrate a fiber optic surface plasmon resonance (SPR) biosensor based on smart phone platforms. The light-weight optical components and sensing element are connected by fibers case. This SPR adaptor can be conveniently installed or removed from phones. measurement, control reference channels illuminated the light entering lead-in phone's LED flash, while end faces of lead-out is detected camera. SPR-sensing fabricated light-guiding silica capillary that stripped off its cladding...
Multi-agent collaborative perception as a potential application for vehicle-to-everything communication could significantly improve the performance of autonomous vehicles over single-agent perception. However, several challenges remain in achieving pragmatic information sharing this emerging research. In paper, we propose SCOPE, novel frame-work that aggregates spatio-temporal awareness characteristics across on-road agents an end-to-end manner. Specifically, SCOPE has three distinct...
Multi-agent collaborative perception has received increasing attention recently as an emerging application in driving scenarios. Despite advancements previous approaches, challenges remain due to redundant communication patterns and vulnerable collaboration processes. To address these issues, we propose What2comm, end-to-end framework achieve a trade-off between performance bandwidth. Our novelties lie three aspects. First, design efficient mechanism based on feature decoupling transmit...
Physicochemical properties of nanomaterials play important roles in determining their toxicological profiles during nano-biointeraction. Among them, surface modification is one the most effective manners to tune cytotoxicity induced by nanomaterials. However, currently, there no consistency including moiety types and quantities considering conflicting particles across different studies. In this study, order systematically investigate how density affects NPs, we chose three functional groups,...
Matrix metalloproteinase (MMP) 2 and 9 are the family members of proteases normally up-regulated in tumor to enhance invasion metastatic cells, associated with poor outcome head neck squamous cell carcinomas (HNSCCs). In present work, MMPs-degradable gelatin nanoparticles (GNPs) simultaneously loaded photosensitizer indocyanine green (ICG) along signal transducer activator transcription 3 (STAT3) inhibitor NSC74859 (NSC, N) for efficient photothermal therapy (PTT) immunotherapy HNSCCs....
Photoexcitation of molecular radicals can produce strong reducing agents; however, the limited lifetimes doublet excited states preclude many applications. Herein, we propose and demonstrate a general strategy to translate highly energetic electron from state ZrO2 insulator, thereby increasing lifetime by about 6 orders magnitude while maintaining potential less than −2.4 V vs SCE. Specifically, red light excitation salicylic acid modified perylene diimide radical anion PDI•– anchored...
With the rapid development of intelligent transportation system applications, a tremendous amount multi-view video data has emerged to enhance vehicle perception. However, performing analytics efficiently by exploiting spatial-temporal redundancy from remains challenging. Accordingly, we propose novel traffic-related framework named CEVAS achieve efficient object detection using data. Briefly, fine-grained input filtering policy is introduced produce reasonable region interest captured...
A new vinyl sulfone (VS) disulfide, 1,2-bis(11-(vinyl sulfonyl)undecyl)disulfane, was synthesized to enable the preparation of VS-presenting self-assembled monolayers (VS SAMs) on Au substrates. The VS SAMs were used as a model system assess reaction kinetics bioactive ligands, i.e., glutathione (GSH), N-(5-amino-1-carboxypentyl)iminodiacetic acid (ab-NTA), and mannose, toward groups SAM surface. ligand immobilization characterized by X-ray photoelectron spectroscopy (XPS), contact angle...
Nonalcoholic fatty liver disease (NAFLD) is a metabolic mainly on account of hypercholesterolemia and may progress to cirrhosis hepatocellular carcinoma. The discovery effective therapy for NAFLD an essential unmet need. Angiopoietin-like protein 3 (ANGPTL3), critical lipid metabolism regulator, resulted in increased blood lipids was elevated NAFLD. Here, we developed nanobody-heavy chain antibody (VHH-Fc) inhibit ANGPTL3 treatment.In this study, retrieved anti-ANGPTL3 VHH Fc fusion protein,...
We present a simple surface plasmon resonance imaging (SPRi) sensing system based on some common optoelectronic devices in this paper. Using an optical fiber SPR sensor as element our system, the SPRi is dramatically compact. A small universal LED used light source. The intensity record images that can be captured by web camera. Microsoft Visual C++6.0 Windows software program written to process image data which contain information. Experimental results show relationship between relative and...
This article demonstrates the catalytic oxa-Michael reaction of inorganic silanol groups with vinyl sulfones, which facilitates an efficient strategy for functionalization silica surface. The was applied on materials ranging from nanoscale to macroscale silica, and surface achieved in hours using organo-catalysts at mild temperature. formation Si–O–C bonds characterized by solid-state 13C cross polarization-magic angle spinning nuclear magnetic resonance spectroscopy, Fourier transform...
This paper reported a facile strategy for the one-pot synthesis of vinyl sulfone (VS) group terminated hydrogel precursors [poly(ethylene) glycol (PEG)-VS] and PEG hydrogels via catalytic oxa-Michael reaction. Nine potential catalysts were investigated reaction between divinyl sulfone, among which 4-dimethylaminopyridine (DMAP) prevailed its high activity. DMAP produced PEG-VS with conversion more than 90% in 2 h under solvent-free condition at room temperature, significantly simplifies...
Atherosclerosis (AS) ultimately cause major adverse cardiovascular events (MACEs). While traditional strategies by lipid-reducing have reduced MACEs, many patients continue to face significant risks. It might attribute the upregulation of CD47 expression in AS lesions, that mediated anti-efferocytosis macrophages. Therefore, we propose simultaneously blocking ANGPTL3, a vital regulator lipid metabolism, and be potential approach for therapy. Firstly, investigate role novel anti-ANGPTL3...
The novel conductive polyvinylidene fluoride (PVDF) fibrous membrane with high conductivity and sensitivity was successfully prepared via electrostatic spinning efficient silver reduction technology. Based on the selective dissolution of porogen polyvinylpyrrolidone (PVP), porous PVDF excellent adsorbability mechanical strength obtained, providing a structure base for preparation nanoparticles (AgNPs-PVDF). Ag+ in AgNO3 mixed solution PVP absorbed maintained inner parts surface structure....