Xiaohui Li

ORCID: 0000-0002-7039-9673
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Adipose Tissue and Metabolism
  • Cerebrovascular and Carotid Artery Diseases
  • Growth Hormone and Insulin-like Growth Factors
  • Bariatric Surgery and Outcomes
  • Eosinophilic Disorders and Syndromes
  • Mosquito-borne diseases and control
  • Multiple Sclerosis Research Studies
  • Liver Disease Diagnosis and Treatment
  • Cardiovascular Disease and Adiposity
  • Venous Thromboembolism Diagnosis and Management
  • Birth, Development, and Health
  • Diet and metabolism studies
  • CRISPR and Genetic Engineering
  • Adipokines, Inflammation, and Metabolic Diseases
  • Thyroid Disorders and Treatments
  • HIV Research and Treatment
  • Immunodeficiency and Autoimmune Disorders
  • Cardiovascular Function and Risk Factors
  • Inflammatory Myopathies and Dermatomyositis
  • Cardiovascular and Diving-Related Complications
  • Epigenetics and DNA Methylation
  • GDF15 and Related Biomarkers
  • Acute Kidney Injury Research
  • High Altitude and Hypoxia

Donghua University
2025

Capital University
2010-2024

Capital Medical University
2010-2024

Nanjing Medical University
2022-2024

Third Hospital of Hebei Medical University
2024

Hebei Medical University
2024

Zhengzhou Central Hospital
2024

Beijing Friendship Hospital
2016-2023

Beijing Obstetrics and Gynecology Hospital
2022-2023

Guangxi University
2023

Objectives. To alleviate the discomfort caused by wet fabric adhering to skin, this study aims examine effects of properties, water saturation and separating velocity on adhesion characteristics between skin. Methods. A novel measurement method was devised assess characteristics, obtained data demonstrated favorable repeatability. Utilizing methodology, 21 fabrics were evaluated under varying saturations velocities. Results. Water exhibited most substantial positive influence both peak force...

10.1080/10803548.2025.2458347 article EN International Journal of Occupational Safety and Ergonomics 2025-02-16

Both obesity and subclinical hypothyroidism (SCH) have adverse effects on human body, but the relationship between these two conditions remains inconsistent. The presence of thyroid autoantibodies influences hormone levels, may further mediate interaction SCH. This study aimed to explore association among obesity, SCH autoantibodies.This was a cross-sectional survey 2505 subjects. Obesity defined as body mass index ≥28 kg/m2. Serum concentrations hormones, peroxidase antibody (TPO-Ab)...

10.1186/s12902-022-00981-0 article EN cc-by BMC Endocrine Disorders 2022-04-08

Objective: In China, high-fat diets and excessive energy intake have led to an increasing prevalence of obesity which was previously uncommon. The current study examined the effects meal replacement (MR) on weight control in overweight or obese Chinese individuals with hyperlipidemia.

10.1080/07315724.2014.989625 article EN Journal of the American College of Nutrition 2015-12-09

Abstract Objective Adipose tissue distribution and glucose metabolism differ between men women. Few studies have investigated sex differences in adipose insulin resistance (adipose-IR). Herein, we adipose-IR adults ranging from overweight to obese the potential factors associated with adipose-IR. Methods A total of 424 had their body mass index (BMI), adipose-IR, hormones evaluated. Based on BMI, males females were assigned 4 groups. Results In total, (n = 156) higher than similar BMI levels...

10.1210/clinem/dgab325 article EN The Journal of Clinical Endocrinology & Metabolism 2021-05-13

Fetal growth restriction (FGR) is a complex obstetric complication with various causes and of great harm. However, the specific pathogenesis FGR unclear, which limits its effective treatment. Gut microbiota dysbiosis was found to be important in diseases. role development remains unclear needs clarified.In our case-control study, we recruited eight control female participants collected their fecal samples third trimester before delivery. We performed metagenomic sequencing bioinformatic...

10.1016/j.retram.2022.103354 article EN cc-by-nc-nd Current Research in Translational Medicine 2022-08-02

Background Vancomycin-associated acute kidney injury (AKI) leads to underestimated morbidity in the intensive care unit (ICU). It is significantly important predict its occurrence advance. However, risk factors and nomograms this AKI are limited. Methods This was a retrospective analysis of two databases. A total 1,959 patients diagnosed with treated vancomycin were enrolled from Medical Information Mart for Intensive Care IV (MIMIC-IV) database. According 7:3 ratio, training set (n = 1,372)...

10.3389/fphar.2024.1389140 article EN cc-by Frontiers in Pharmacology 2024-08-28

Bariatric surgery has become the most effective treatment for morbid obesity. Increasing evidence showed that bariatric can alleviate insulin resistance and influence thyroid function. This study aimed to investigate relationship between changes in function adipose tissue (adipo-IR) after surgery.A total of 287 non-diabetic participants with regular were recruited divided into lean, overweight obese groups. Among them, 50 morbidly patients submitted surgery.The group had a higher level...

10.1530/ec-21-0360 article EN cc-by-nc-nd Endocrine Connections 2021-09-15

Human immunodeficiency virus type one (HIV-1) is the leading cause of acquired syndrome (AIDS). AIDS remains a global public health concern but can be effectively suppressed by life-long administration combination antiretroviral therapy. Early detection and diagnosis are two key strategies for prevention control HIV/AIDS. Rapid accurate point-of-care testing (POCT) provides critical tools managing HIV-1 epidemic in high-risk areas populations.In this study, POCT RNA was developed...

10.1186/s12879-023-08492-6 article EN cc-by BMC Infectious Diseases 2023-09-25

Background: Hyperglycaemia is thought to be connected worse functional outcomes after ischaemic stroke. However, the association between hyperglycaemia and acute kidney injury (AKI) endovascular treatment (EVT) remains elusive. The purpose of this study was investigate influence glycaemic on AKI EVT. Methods: We retrospectively collected clinical information patients who underwent EVT from April 2015 August 2021. Blood glucose recorded as glycaemia. Chronic levels were estimated by...

10.3390/jcm11133865 article EN Journal of Clinical Medicine 2022-07-03

Few clinical studies have assessed Rho kinase (ROCK) in patients with dia-betes mellitus (DM) and ST-segment elevation myocardial infarction (STEMI). This study aimed to determine whether ROCK activity circulating leukocytes is increased STEMI DM predicts the onset of cardiovascular events.Blood samples were collected from 60 patients, divided into non-diabetes (NDM) groups. Main outcome measures all-cause mortality, readmission for acute coronary syndrome (ACS), congestive heart failure...

10.5603/cj.a2016.0031 article EN Cardiology Journal 2016-06-20

Few studies have yet investigated the possible association between high-density lipoprotein cholesterol (HDL-C) and kidney function in elderly patients with primary hypertension. Accordingly, aim of present study was to evaluate relationship HDL-C A total 14,644 hypertensive subjects were enrolled our cross-sectional study. The categorized based on serum level glomerular filtration rate (GFR) value, respectively. One-way analysis variance used compare parameters among different groups....

10.1097/md.0000000000000651 article EN cc-by-nc Medicine 2015-04-01

Background: Bariatric surgery has a significant effect on weight loss and improves adipose tissue insulin resistance (adipose-IR); however, the underlying mechanism remains unclear. This study aimed to investigate of growth hormone (GH) adipose-IR improvement after bariatric in patients with obesity. Methods: A prospective cohort 1-year follow-up was conducted China-Japan Friendship Hospital. Pre- postoperative variables, including body mass index (BMI), glucose lipid metabolic indicators,...

10.1089/met.2023.0034 article EN Metabolic Syndrome and Related Disorders 2023-06-23

Objective: Higher fasting glucose is thought to be associated with adverse outcome in patients receiving endovascular treatment (EVT), while the effect of glycosylated hemoglobin (HbA1c) on controversial. We combined blood (FBG) HbA1c and evaluated their relationship three-month functional who underwent EVT. Methods: Data from 739 consecutive ischemic stroke EVT April 2015 August 2021 were retrospectively reviewed. was used estimate chronic level according following formula: (mg/dL) = 28.7 ×...

10.3390/brainsci12111576 article EN cc-by Brain Sciences 2022-11-18

Backgrounds: The patients with acute pancreatitis (AP) were commonly presented thyroid dysfunction in clinic. present study aimed to assess the characteristics and risk factors of AP changes it improvement explore its value for predicting severity AP. Methods: A total 182 61 age- gender-matched chronic (CP) enrolled. data demography, biochemical indicators function collected analyze. Results: average age was 53.3±16.7 years 61.5% males 52.7±11.9 CP 59.0% males. Compare group, level T3, T4,...

10.2139/ssrn.4807010 preprint EN 2024-01-01

The clinical symptoms of neuromyelitis optica spectrum disorder (NMOSD) and acute cervical spondylotic myelopathy (CSM) may overlap in some cases. This study aimed to investigate the differences imaging features between NMOSD CSM myelopathy.

10.1186/s12883-024-03884-w article EN cc-by-nc-nd BMC Neurology 2024-10-02

<title>Abstract</title> <bold>Objective </bold>This study aimed to investigate the clinical characteristics and risk factors for pruritus in patients with neuromyelitis optica spectrum disorders (NMOSD) evaluate its impact on patient quality of life. <bold>Methods </bold>Patients NMOSD at Department Neurology our hospital from December 2021 August 2023 were followed up by outpatient visits or telephone interviews. The 5-D itch scale was used intensity, course pruritus-related interference...

10.21203/rs.3.rs-5001368/v1 preprint EN cc-by Research Square (Research Square) 2024-10-18

Abstract Background Human immunodeficiency virus type one (HIV-1) is the leading cause of acquired syndrome (AIDS). AIDS remains a global public health concern but can be effectively suppressed by life-long administration combination antiretroviral therapy. Early detection and diagnosis are two key strategies for prevention control HIV/AIDS. Rapid accurate point-of-care testing (POCT) provides critical tools managing HIV-1 epidemic in high-risk areas populations. Methods In this study, POCT...

10.21203/rs.3.rs-2711381/v1 preprint EN cc-by Research Square (Research Square) 2023-04-03

Adipose tissue distribution and glucose metabolism differ from adults with normal weight to obesity. Growth hormone (GH) is closely related Few studies have investigated the role of GH in adipose insulin resistance (Adipo-IR). Herein, we level Adipo-IR ranging obesity potential association between Adipo-IR.A total 1,017 participants had their body mass index (BMI), GH, evaluated. Based on BMI, were assigned five groups class 3 obesity; based tertiles, divided into low-, medium-, high-GH...

10.1159/000530734 article EN cc-by-nc Obesity Facts 2023-01-01

Objective. To explore the associations between type 2 diabetes mellitus (DM) and stroke by evaluating clinical risk factors, characteristics, outcomes of acute ischemic (AIS) patients with without DM. Methods. A total 1,156 AIS (including 410 DM (AIS-DM group)) 746 (AIS-NDM were included. Patients’ demographics, auxiliary examinations, manifestations, treatment recorded analyzed. Results. Among included patients, 35.46% had The AIS-DM group less males (59.76% versus 70.64%), smokers (33.90%...

10.1155/2021/5517228 article EN cc-by International Journal of Endocrinology 2021-06-14

Background Cardiovascular risk due to obesity can be improved greatly by bariatric surgery. However, there is no research involving appropriate model for evaluating cardiovascular disease reduction in surgery China. We selected the ischemic (ICVD) score that accurately predict Chinese adults evaluate 10-year of ICVD and estimated early benefits obese patients through its reduction. Methods From 2017 2019 we followed up 107 6 months after measured other factors before Results There were...

10.3389/fcvm.2022.978682 article EN cc-by Frontiers in Cardiovascular Medicine 2022-10-11
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