Doron Sudarsky

ORCID: 0000-0002-7067-6706
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About
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Research Areas
  • Cardiac Valve Diseases and Treatments
  • Cardiac Health and Mental Health
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Structural Anomalies and Repair
  • Cardiac pacing and defibrillation studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Acute Myocardial Infarction Research
  • Cardiovascular Function and Risk Factors
  • Cardiac Imaging and Diagnostics
  • Acute Kidney Injury Research
  • Acute Ischemic Stroke Management
  • Circular RNAs in diseases
  • Renal and Vascular Pathologies
  • Congenital Heart Disease Studies
  • Venous Thromboembolism Diagnosis and Management
  • Atrial Fibrillation Management and Outcomes
  • Heart Rate Variability and Autonomic Control
  • MicroRNA in disease regulation
  • Cardiovascular and exercise physiology
  • Pharmaceutical industry and healthcare
  • Cardiac Arrest and Resuscitation
  • Mechanical Circulatory Support Devices
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Streptococcal Infections and Treatments
  • Trauma, Hemostasis, Coagulopathy, Resuscitation

Poriya Medical Center
2019-2025

Bar-Ilan University
2019-2023

Technion – Israel Institute of Technology
2011-2015

Emek Medical Center
2014-2015

London Health Sciences Centre
2013

Western University
2013

Severe mitral regurgitation (MR) following acute myocardial infarction (MI) is associated with high mortality rates and has inconclusive recommendations in clinical guidelines. We aimed to report the international experience of patients secondary MR MI compare outcomes those treated conservatively, surgically, percutaneously.Retrospective registry consecutive at least moderate-to-severe 21 centres North America, Europe, Middle East. The included conservatively having surgical valve repair or...

10.1093/eurheartj/ehab496 article EN European Heart Journal 2021-07-23

Abstract Objectives To assess outcomes in patients with acute mitral regurgitation (MR) following myocardial infarction (AMI) who received percutaneous valve repair (PMVR) the MitraClip device and to compare of developed cardiogenic shock (CS) those did not (non‐CS). Background Acute MR after AMI may lead CS is associated high mortality. Methods This registry analyzed were treated at 18 centers within eight countries between January 2016 February 2020. Patients stratified into non‐CS groups....

10.1002/ccd.29552 article EN Catheterization and Cardiovascular Interventions 2021-02-18

Development of contrast-induced nephropathy (CIN), ie, a rise in serum creatinine by either ≥0.5 mg/dL or ≥25% from baseline within the first 2-3 days after contrast administration, is strongly associated with both increased inhospital and late morbidity mortality invasive cardiac procedures. The prevention CIN critical if long-term outcomes are to be optimized percutaneous coronary intervention. prevalence patients receiving varies markedly (from <1% 50%), depending on presence well...

10.2147/ijnrd.s21393 article EN cc-by-nc International Journal of Nephrology and Renovascular Disease 2011-07-01

Abstract Aims Acute mitral regurgitation (MR) in the setting of myocardial infarction (MI) may be result papillary muscle rupture (PMR). This condition is associated with high morbidity and mortality. We aim to evaluate feasibility transcatheter edge‐to‐edge valve repair (TEER) this acute setting. Methods results analysed data from International Registry MitraClip Mitral Regurgitation following Myocardial Infarction (IREMMI) 30 centres Europe, North America, middle east. included patients...

10.1002/ehf2.14675 article EN cc-by-nc-nd ESC Heart Failure 2024-02-01

Abstract Background Severe pain is prevalent in cardiac surgery patients and can increase complications, morbidity mortality. The objectives of the study were to assess perioperative intensity predictors post-cardiac surgery, including clinical characteristics depression. Methods A total 98 included study. Pain was assessed using a Numerical Rating System. measured one day pre-operatively recorded daily from Post-operative Day 2 7. Clinical data depression scores Center for Epidemiological...

10.1186/s12871-022-01740-3 article EN cc-by BMC Anesthesiology 2022-07-04

Patients with severe mitral regurgitation (MR) after myocardial infarction (MI) have an increased risk of mortality. Transcatheter valve repair may therefore be a suitable therapy. However, data on clinical outcomes patients in acute setting are scarce, especially those reduced left ventricle (LV) dysfunction. We conducted multinational, collaborative analysis from 21 centers for who were, within 90 days MI, treated MitraClip due to MR. The cohort was divided according median ejection...

10.3390/jcm10091819 article EN Journal of Clinical Medicine 2021-04-22

Anemia in patients with acute coronary syndromes (ACS) is strongly related to the increased risk of bleeding and mortality. Whether benefit early invasive strategy exceeds these unknown.To assess impact angiography on outcomes ACS baseline anemia.Biennial Israeli registry (ACSIS) prospectively collects data from all 26 public hospitals. The endpoints included rates in-hospital major bleeding, as well 30-day 1-year at was present 1,464 5,600 (26.1%). Coronary within index hospitalization...

10.1111/joic.12216 article EN Journal of Interventional Cardiology 2015-07-03

Background Multiple contrast media exposures are common, but their cumulative effect on renal function is unknown. We aimed to investigate the consequences of repeated with coronary interventions. Methods and Results studied 2942 patients who underwent between 1 9 procedures. The primary end point was a persistent creatinine increase ≥50% above baseline at ≥90 days after last procedure. dose assessed using Cox models, exposure as time-dependent variable, propensity score matching. occurred...

10.1161/jaha.121.021473 article EN cc-by-nc-nd Journal of the American Heart Association 2021-09-17

The effect of contrast media (CM), delivered prior to- and during transcatheter aortic valve implantation (TAVI), on kidney function, following the procedure, is debatable. Consequently, performance CM-based, acute injury (AKI) risk prediction models also questionable. We retrospectively studied 210 patients that underwent TAVI. recorded dose CM used TAVI, calculated results different AKI assessment containing a module, tested their association with after procedure. was diagnosed in 38...

10.3390/jcm11051181 article EN Journal of Clinical Medicine 2022-02-23

&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; Risk stratification in patients post-transcatheter aortic valve replacement (TAVR) is limited to and based on clinical judgment surgical scoring systems. Serum natriuretic peptides are used for general risk with stenosis, reflecting the increase their afterload thereby stressing need intervention. The objective of this study was determine predictive value pre- post-procedural serum brain peptide (BNP) 1-year all-cause mortality who underwent...

10.1159/000509857 article EN Cardiology 2020-01-01

Coronary artery disease (CAD) is the leading cause of mortality worldwide. In chronic and myocardial infarction (MI) states, aberrant levels circulating microRNAs compromise gene expression pathophysiology. We aimed to compare microRNA in chronic-CAD acute-MI male patients peripheral blood vasculature versus coronary arteries proximal a culprit area. Blood from chronic-CAD, with/out ST segment elevation (STEMI/NSTEMI, respectively), control lacking previous CAD or having patent was collected...

10.3390/ijms24108551 article EN International Journal of Molecular Sciences 2023-05-10

Coronary artery calcium measured by CT predicts future coronary events. Similarly, carotid on dental panoramic radiographs has been associated with increased cardiovascular Pre-procedural assessment of candidates for valve replacement in our institution includes and chest tomography. We aimed to assess the association tomography.Paired pre-procedural tomography scans were done 177 consecutive patients between October 2016 2017. Carotid was quantified using NIH's ImageJ. Agatston score...

10.1259/dmfr.20200174 article EN Dentomaxillofacial Radiology 2020-08-05

Mitral regurgitation (MR) is frequently associated with severe aortic stenosis (AS). Significant MR less favorable prognosis after transcatheter valve implantation (TAVI), including higher early and late mortality rate. The severity of improved in about half patients undergoing TAVI. However, the predictors improvement TAVI are unknown. We sought to investigate whether several demographic, clinical, echocardiographic laboratory parameters procedure characteristics predictive procedure.A...

10.14740/cr1174 article EN Cardiology Research 2020-12-12

Background: Conventional echocardiography used to assess volumes of the left ventricle (LV) and atrium (LA) along with mitral regurgitation grade is routine studies before after transcatheter edge-to-edge valve repair (Mitral TEER). Previous focus on LV parameter changes comparison functions a few months following Mitral TEER implantation, as well LA reverse remodeling, by assessing volumes. However, less known regarding strain in early phase procedure. The objective study was effect...

10.20944/preprints202410.2423.v1 preprint EN 2024-10-30

Conventional echocardiography used to assess volumes of the left ventricle (LV) and atrium (LA) along with mitral regurgitation grade is routine in studies before after transcatheter edge-to-edge valve repair (Mitral TEER). Previous focus on LV parameter changes comparison functions a few months following Mitral TEER implantation, as well LA reverse remodeling, by assessing volumes. However, less known regarding strain early phase procedure. The objective study was effect

10.3390/jcm13237282 article EN Journal of Clinical Medicine 2024-11-29

The development of malignant pericardial effusion indicates a poor prognosis and is the leading cause cardiac tamponade. objectives study were to examine levels BNP in traumatic, non-malignant etiologies, assess value serum fluid effusion.A 56 patients with clinical echocardiographic diagnosis pre-tamponade or tamponade who required pericardiocentesis included study. assessed within fluid. diagnostic discriminating between non- etiology was examined using receiver-operating characteristic...

10.1016/j.ijcha.2019.100359 article EN cc-by-nc-nd IJC Heart & Vasculature 2019-04-09
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