Estefanía Fernández‐Peregrina
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Coronary Interventions and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Mechanical Circulatory Support Devices
- Cardiac pacing and defibrillation studies
- Advanced X-ray and CT Imaging
- Cardiovascular Issues in Pregnancy
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Peripheral Artery Disease Management
- Cardiovascular Disease and Adiposity
- Cardiac Arrhythmias and Treatments
- Blood Pressure and Hypertension Studies
- Cardiac Arrest and Resuscitation
- Hemodynamic Monitoring and Therapy
- Thermoregulation and physiological responses
- Cardiovascular and Diving-Related Complications
- Transplantation: Methods and Outcomes
- Aortic aneurysm repair treatments
Hospital de Sant Pau
2020-2025
Centro de Investigación Biomédica en Red
2022-2023
Centro de Investigación en Red en Enfermedades Cardiovasculares
2022-2023
Universitat Autònoma de Barcelona
2020-2023
MedStar Washington Hospital Center
2021-2022
Onze Lieve Vrouwziekenhuis Hospital
2021-2022
Washington Hospital
2022
Institute of Cardiology
2021
Abstract Background and Aims Risk stratification for mitral valve transcatheter edge-to-edge repair (M-TEER) is paramount in the decision-making process to appropriately select patients with severe secondary regurgitation (SMR). This study sought develop validate an artificial intelligence-derived risk score (EuroSMR score) predict 1-year outcomes (survival or survival + clinical improvement) SMR undergoing M-TEER. Methods An was developed from EuroSMR cohort (4172 428 treated M-TEER...
Severe mitral regurgitation (MR) following acute myocardial infarction (MI) is associated with high mortality rates and has inconclusive recommendations in clinical guidelines. We aimed to report the international experience of patients secondary MR MI compare outcomes those treated conservatively, surgically, percutaneously.Retrospective registry consecutive at least moderate-to-severe 21 centres North America, Europe, Middle East. The included conservatively having surgical valve repair or...
Background: Coronary microvascular dysfunction (CMD) is an early feature of diabetic cardiomyopathy, which usually precedes the onset diastolic and systolic dysfunction. Continuous intracoronary thermodilution allows accurate reproducible assessment absolute coronary blood flow resistance thus allowing evaluation reserve (CFR) Microvascular Resistance Reserve (MRR), a novel index specific for function, independent from myocardial mass. In present study we compared resistance, CFR MRR...
Abstract Objectives To assess outcomes in patients with acute mitral regurgitation (MR) following myocardial infarction (AMI) who received percutaneous valve repair (PMVR) the MitraClip device and to compare of developed cardiogenic shock (CS) those did not (non‐CS). Background Acute MR after AMI may lead CS is associated high mortality. Methods This registry analyzed were treated at 18 centers within eight countries between January 2016 February 2020. Patients stratified into non‐CS groups....
Objective Left atrial appendage (LAA) thrombus has heretofore been considered a contraindication to percutaneous LAA closure (LAAC). Data regarding its management are very limited. The aim of this study was analyse the medical and invasive treatment patients referred for LAAC in presence thrombus. Methods This multicentre observational registry included 126 consecutive with on preprocedural imaging. Treatment strategies intensification antithrombotic therapy (IAT) or direct LAAC. primary...
Background: Transcatheter mitral valve repair (TMVR) is an effective therapy for high-risk patients with severe regurgitation (MR) but heart failure (HF) readmissions and death remain substantial on mid-term follow-up. Recently, right ventricular (RV) to pulmonary arterial (PA) coupling has emerged as a relevant prognostic predictor in HF. In this study, we aimed assess the value of tricuspid annular plane systolic excursion (TAPSE) PA pressure (PASP) ratio non-invasive measure RV-to-PA...
MAC is commonly found in patients affected with MR, and it associated high morbidity, mortality worse cardiac surgical outcomes. Transcatheter edge-to-edge repair could be an alternative treatment, although there little evidence this population.The aim of study was to analyse the safety, efficacy durability MitraClip implantation mitral regurgitation (MR) annulus calcification (MAC).We analysed outcomes 61 suitable severe MR moderate or (the "MAC" group) 791 no mild "NoMAC" treated...
Background Malnutrition is associated with poor prognosis in several cardiovascular diseases. However, its prognostic impact patients undergoing transcatheter edge-to-edge mitral valve repair (TEER) not well known. This study sought to assess the prevalence, clinical associations, and consequences of malnutrition TEER. Methods Results A total 892 TEER from international MIVNUT (Mitral Valve Repair Nutritional Status) registry were studied. status was assessed Controlling Status score. The...
Coronary microvascular dysfunction (CMD) has been proposed as a key mechanism in Takotsubo syndrome (TTS). The non-hyperaemic angiography-derived index of microcirculatory resistance (NH-IMRangio) validated pressure-wire-free tool for the assessment coronary microvasculature. We aimed to study presence CMD TTS patients and its association with levels cardiac biomarkers systolic patterns. recruited 181 consecutive admitted who underwent angiography at tertiary center from January 2014 2021....
Microvascular resistance reserve (MRR) as derived from continuous intracoronary thermodilution specifically quantifies microvasculature function. As originally described, the technique necessitates reinstrumentation of artery and manual reprogramming infusion pump when performing resting hyperemic measurements. To simplify to render this procedure operator-independent, we developed a fully automated method. The aim present study is validate against described one.For procedure, an was...
Patients with severe mitral regurgitation (MR) after myocardial infarction (MI) have an increased risk of mortality. Transcatheter valve repair may therefore be a suitable therapy. However, data on clinical outcomes patients in acute setting are scarce, especially those reduced left ventricle (LV) dysfunction. We conducted multinational, collaborative analysis from 21 centers for who were, within 90 days MI, treated MitraClip due to MR. The cohort was divided according median ejection...
Using proteomics, we previously found that serum levels of glycosylated (Glyc) forms apolipoprotein J (ApoJ), a cytoprotective and anti-oxidant protein, decrease in the early phase acute myocardial infarction (AMI). We aimed to investigate: (i) ApoJ-Glyc intracellular distribution secretion during ischaemia; (ii) changes circulating AMI; (iii) associations between residual ischaemic risk post-AMI.Glycosylated was investigated in: cells from different organ/tissue origin; pig model de novo...
Intravascular lithotripsy (IVL) combined with rotational atherectomy (RA), known as Rotatripsy, is used to treat severe coronary artery calcification (CAC), though data on efficacy, midterm safety and use sequence limited. We aimed identify indicators for Rotatripsy assess its success rates, both acutely at 1-year follow-up.