A5083172982- 3D Printing in Biomedical Research
- Additive Manufacturing and 3D Printing Technologies
- Mechanical Behavior of Composites
- Polymer crystallization and properties
- Injection Molding Process and Properties
- Polymer composites and self-healing
- Epoxy Resin Curing Processes
- Polymer Nanocomposites and Properties
- Polymer Foaming and Composites
- Advanced Drug Delivery Systems
- Sports Dynamics and Biomechanics
- Innovative Microfluidic and Catalytic Techniques Innovation
- Manufacturing Process and Optimization
- Rheology and Fluid Dynamics Studies
- Advanced Sensor and Energy Harvesting Materials
- Hydrogels: synthesis, properties, applications
- Drug Solubulity and Delivery Systems
- Cystic Fibrosis Research Advances
- Lower Extremity Biomechanics and Pathologies
- Pickering emulsions and particle stabilization
- biodegradable polymer synthesis and properties
- Innovations in Concrete and Construction Materials
- Gut microbiota and health
- Elasticity and Material Modeling
- Electrospun Nanofibers in Biomedical Applications
Politecnico di Milano
2016-2025
Mylan (South Africa)
2019
Mylan (Switzerland)
2019
Tecnologia Energia Ambiente Materiali (Italy)
2010
Texas Tech University
2002
Abstract The development of 3D soft‐robotic components is currently hindered by material limitations associated with conventional printing techniques. To overcome this challenge, an indirect approach based on the fabrication printed sacrificial templates proposed. High‐resolution micromolds produced direct laser writing are infused polymers and then dissolved, leading to final soft microstructures. This method used indirectly print 4D microrobots. versatility technique shown through...
Abstract Variable stiffness catheters are typically composed of an encapsulated core. The core is usually a low melting point alloy (LMPA) or thermoplastic polymer (TP). In both cases, there need to encapsulate the with elastic material. This imposes limit volume variable (VS) material and limits miniaturization. paper proposes new approach that relies on use thermosetting materials. catheter (VSC) proposed in this work eliminates necessity for encapsulation layer made unique biocompatible...
The pulsatile-release Chronotopic™ system was conceived of as a drug-containing core surrounded by coat made swellable/soluble hydrophilic polymers, the latter being able to provide programmable lag phase prior drug liberation. This also proposed in colon-targeting configuration, entailing gastroresistant film prevent early interaction inner with gastric fluids and enabling attainment matching small intestinal transit time. Over years, various multiple-step manufacturing processes have been...
Hyaluronic acid (HA) is a versatile biomaterial frequently utilized in regenerative medicine due to its gel-like properties, making it well-suited for clinical applications. However, linear form susceptible rapid enzymatic degradation, limiting longevity within the body. To address this challenge, extensive research has focused on crosslinking mechanisms enhance durability of HA gels. One early approach involved with 1,4-butanediol diglycidyl ether (BDDE) create HA-BDDE, clinically used...
Among the many approaches to improve performance of lithium-metal batteries, ternary polyethylene oxide/ionic liquid/lithium salt electrolytes offer several advantages such as low flammability, high conductivity (vs. oxide/lithium electrolytes) and, a large extent, limiting growth dendrites at moderate currents. However, they suffer from relatively mechanical strength for lithium metal confinement. Besides, transport numbers are very low, which is conducive depletion during plating current...
Abstract In polyjet printing photopolymer droplets are deposited on a build tray, leveled off by roller and cured UV light. This technique is attractive to fabricate heterogeneous architectures combining compliant stiff constituents. Considering the layer-by-layer nature, interfaces between different photopolymers can be formed either before or after curing. We analyzed properties of in 3D printed composites experiments with computer simulations. To investigate blending, we characterized...
Supramolecular eutectogels are an emerging class of materials consisting deep eutectic solvents (DESs) confined in a semisolid 3D network by polymers or gelation process. These soft have applications many areas, due to the dynamic nature noncovalent interactions that form gel network, which makes them stimuli-responsive systems. Herein, we report preparation and characterization hydrophobic eutectogels, obtained gelling nonionic type V DESs, as controlled drug delivery The supramolecular...
Pullulan is a natural polysaccharide used in many health products, including dry powders for oral and pulmonary administration. In these cases, the control of shape dimensions particles crucial obtaining desired functionality. Different from other polysaccharides, pullulan cannot be easily shaped without chemical modifications or adjuvants’ addition. This work aims to systematically investigate impact solvent composition polymer concentration on possibility tuning particle by spray drying....
The reason why certain bacteria, e.g., Pseudomonas aeruginosa (PA), produce acetylated alginate (Alg) in their biofilms remains one of the most intriguing facts microbiology. Being main structural component...
In the last years, 3D bioprinting has gained great interest for development of advanced models aimed at biological high-throughput studies. Despite potentialities, some technical challenges still need to be addressed. Among those is necessity creating a bioink formulation that can ensure high batch-to-batch replicability as well good biocompatibility and mild curing conditions cell encapsulation. Within this context, polymer formulations capable reversible sol–gel transitions upon...
Mucus is a natural barrier with protective role that hinders drug diffusion, representing steric and interactive to overcome for an effective delivery target sites.
3D-Reactive printing brings a new perspective for the 3D-printing of alginate-based inks. Printability was achieved through tuning crosslinking kinetics, without changing composition inks or use additives.