A5062272570- Cancer survivorship and care
- Cancer-related cognitive impairment studies
- Childhood Cancer Survivors' Quality of Life
- Palliative Care and End-of-Life Issues
- Tryptophan and brain disorders
- Family Support in Illness
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Economic and Financial Impacts of Cancer
- Health Systems, Economic Evaluations, Quality of Life
- Anesthesia and Pain Management
- Health, psychology, and well-being
- Intensive Care Unit Cognitive Disorders
- Frailty in Older Adults
- Chronic Disease Management Strategies
- Cancer, Stress, Anesthesia, and Immune Response
- Global Cancer Incidence and Screening
- Lymphatic System and Diseases
- Breast Cancer Treatment Studies
- Nerve Injury and Rehabilitation
- IL-33, ST2, and ILC Pathways
- Advanced Breast Cancer Therapies
- Music Therapy and Health
- Hospital Admissions and Outcomes
- Multiple and Secondary Primary Cancers
Florida College
2024
University of Florida
2024
New York University
2018-2024
Harvard Pilgrim Health Care
2024
Harvard University
2024
Icahn School of Medicine at Mount Sinai
2021-2023
Women's Resource Center
2023
National Institute on Aging
2021
University of Michigan
2021
University of North Carolina at Chapel Hill
2021
Pain, fatigue, sleep disturbance, and depression are common frequently co-occurring symptoms in oncology patients. This symptom cluster is often attributed to the release of proinflammatory cytokines. The purposes this study were determine whether distinct latent classes patients with breast cancer (n = 398) could be identified based on their experience cluster, these differed demographic clinical characteristics variations cytokine genes associated class membership. Three identified: "all...
Abstract Background Mortality rates for cancer are decreasing in patients under 60 and increasing those over years of age. The reasons these differences mortality remain poorly understood. One explanation may be that older received substandard treatment because concerns about adverse effects. Given the paucity research on multiple dimensions symptom experience oncology patients, purpose this study was to evaluate ratings occurrence, severity, frequency, distress between younger (< years)...
BACKGROUND The purpose of this study was to examine and compare the effects first 18 months anastrozole therapy on cognitive function in women with breast cancer. METHODS This large, longitudinal cohort composed postmenopausal early‐stage cancer who received chemotherapy plus (n = 114) or alone 173) a control group 110). Cognitive assessed before systemic 6, 12, after initiation at comparable time points controls. RESULTS chemotherapy‐anastrozole anastrozole‐alone groups had poorer executive...
The purposes of this study were to identify distinct latent classes individuals based on subjective reports sleep disturbance; examine differences in demographic, clinical, and symptom characteristics between the classes; evaluate for variations pro- anti-inflammatory cytokine genes classes. Among 167 oncology outpatients with breast, prostate, lung, or brain cancer 85 their FCs, growth mixture modeling (GMM) was used General Sleep Disturbance Scale (GSDS) obtained prior to, during, four...
Lymphedema (LE) is a frequent complication following breast cancer treatment. While progress being made in the identification of phenotypic risk factors for development LE, little information available on molecular characterization LE. The purpose this study was to determine if variations pro- and anti-inflammatory cytokine genes were associated with LE treatment.Breast patients completed number self-report questionnaires. evaluated using bioimpedance spectroscopy. Genotyping done custom...
In a sample of 368 postmenopausal women, we (1) determined within-cohort and between-cohort relationships between adjuvant systemic therapy for breast cancer self-reported cognitive function during the first 18 months (2) evaluated influence co-occurring symptoms, neuropsychological function, other covariates on relationships.We using Patient Assessment Own Functioning Inventory (PAOFI), potential (e.g., symptom scores z-scores) in 158 women receiving aromatase inhibitor (AI) alone, 104...
The purpose of this study was to evaluate for differences in variations pro- and anti-inflammatory cytokine genes between participants who were classified as having low high levels morning evening fatigue phenotypic characteristics these two groups. In a sample 167 oncology outpatients with breast, prostate, lung, or brain cancer 85 their family caregivers, growth mixture modeling used identify latent classes individuals based on ratings obtained prior to, during, 4 months following...
A cancer diagnosis as an adolescent and young adult (AYA) poses exceptional challenges, including potential greater financial toxicity than older survivors experience who have had more time for career establishment to build assets. Costs patients increased the past decade; prospects AYA long-term survival also increased. better understanding of what is, how it presents, immediate longer-term implications AYAs is needed.The aim this study was analyze concept in diagnosed with cancer.We used...
Preoperative breast pain in women with cancer may result from a number of causes. Previous work our team found that occurred 28.2% (n = 398) who were about to undergo surgery. The occurrence preoperative was associated demographic and clinical characteristics, as well variation two cytokine genes. Given ion channels regulate excitability sensory neurons, we hypothesized variations potassium channel genes would be these patients. Therefore, this study, evaluated for associations between...
This study identified women with unique trajectories of executive function, concentration, and visual working memory before during adjuvant therapy for breast cancer, examined phenotypic genotypic predictors associated subgroups.399 postmenopausal women, whom 288 were early-stage cancer 111 without matched on age years education to the all at an urban center.A repeated-measures design was used; assessments occurred every six months post-therapy initiation. Group-based trajectory modeling...
Background: Attentional fatigue is experienced as a decreased ability to concentrate, engage in purposeful activity, and maintain social relationships when there are competing demands on attention. Breast prostate cancer the 2 most common cancers women men, respectively. Most previous studies self-reported attentional evaluated patients with breast cancer. Objectives: The objectives of study were determine if differed before radiation therapy (RT) between other symptoms these groups....
Subgroups of individuals may be at greater risk cytokine-induced changes in attentional function. The purposes this study were to identify subgroups with distinct trajectories function and evaluate for phenotypic genotypic (i.e., cytokine gene polymorphisms) differences among these subgroups. Self-reported was evaluated 252 participants (167 oncology patients 85 family caregivers) using the Attentional Function Index before radiation therapy six additional assessments over 6 months. Three...