A5036750416- Cancer-related cognitive impairment studies
- Glioma Diagnosis and Treatment
- Cancer survivorship and care
- Brain Metastases and Treatment
- Chronic Lymphocytic Leukemia Research
- Childhood Cancer Survivors' Quality of Life
- Dementia and Cognitive Impairment Research
- French Urban and Social Studies
- Child Nutrition and Water Access
- Tryptophan and brain disorders
- Family Support in Illness
- Epigenetics and DNA Methylation
- Palliative Care and End-of-Life Issues
- RNA modifications and cancer
- Cancer Treatment and Pharmacology
- Central Venous Catheters and Hemodialysis
- Mental Health and Patient Involvement
- Advances in Oncology and Radiotherapy
- Drug-Induced Adverse Reactions
- Management of metastatic bone disease
- Chronic Myeloid Leukemia Treatments
- Cancer, Hypoxia, and Metabolism
- Protein Degradation and Inhibitors
- Sleep and related disorders
- Pharmacovigilance and Adverse Drug Reactions
Bristol-Myers Squibb (Germany)
2025
University of Kansas
2014-2024
Asuragen (United States)
2024
R&D Systems (United States)
2024
University of Kansas Medical Center
2009-2023
Japan Society for the Promotion of Science
2022
The University of Kansas Cancer Center
2020-2022
Rajiv Gandhi University
2022
Penrose-St. Francis Health Services
2022
Hiroshima University
2022
To provide an in-depth description of the experience chemotherapy-related cognitive impairment (CRCI) for women with breast cancer and identify related information that would find useful prior to chemotherapy at onset changes.Qualitative, descriptive design.Academic survivorship center in Kansas City, KS.18 survivors within 6-12 months having completed who self-reported changes function.Data were collected a demographic questionnaire, semistructured interviews, focus group. Qualitative...
To test the feasibility of sleep hygiene education and longitudinal wrist actigraph metrics measurement alone versus in combination with telehealth-delivered cognitive behavioral therapy for insomnia (teleCBT-I) people prostate cancer (PC) receiving androgen deprivation (ADT). 45 men PC ADT were recruited from a midwestern comprehensive center. Participants provided actigraphs, their individual data, education. Half sample was randomized to four-week teleCBT-I intervention. Outcomes...
Chemotherapy-related cognitive impairment (CRCI) was first described in the 1970s, but significant recognition of CRCI did not emerge with consistency until late 1990s. Estimates frequency now range from 17%-75%, and evidence suggests that CRCI, or "chemobrain" as it is referred to lay literature, concern patients. A variety potentially associated factors have been identified, including age, education level, intelligence, social support; anxiety, depression, fatigue; disease site, stage,...
In a sample of 368 postmenopausal women, we (1) determined within-cohort and between-cohort relationships between adjuvant systemic therapy for breast cancer self-reported cognitive function during the first 18 months (2) evaluated influence co-occurring symptoms, neuropsychological function, other covariates on relationships.We using Patient Assessment Own Functioning Inventory (PAOFI), potential (e.g., symptom scores z-scores) in 158 women receiving aromatase inhibitor (AI) alone, 104...
Study purpose: The aim of this study was to further explore the lived experiences women with metastatic breast cancer (MBC), inform development interventions enhance survivorship care for advanced disease. Methodology: Four semi-structured focus groups were conducted MBC. data analysed using qualitative content analysis. Results: Participants described challenges living uncertainty, as a result lack information regarding treatment options and symptom management, sense unknown related...
The Fred Hutchinson Cancer Research Center has engaged an External Stakeholder Advisory Group (ESAG) in the planning and implementation of TrACER Study (S1415CD), a five-year pragmatic clinical trial assessing effectiveness guideline-based colony stimulating factor standing order intervention. is being conducted by SWOG through National Institute Community Oncology Program 45 clinics. ESAG includes ten patient partners, two payers, pharmacists, guideline experts, four providers one medical...
Abstract Purpose of Review This review describes case reports for patients with kratom-associated adverse events in order to assist clinicians patient management. A stepwise approach is proposed assessing active kratom users as well considerations the management toxicities or withdrawal. Recent Findings Multiple vitro and vivo studies illustrate pharmacologic toxicologic effects extract. No randomized controlled trials humans exist that assess safety efficacy substance. Cross-sectional...
Abstract Background Patients prefer medical communication including both hopefulness and realism, though health-care professional (HCPs) struggle to balance these. Providers could thus benefit from a detailed personal understanding of hope, allowing them model convey it patients. Additionally, given that hope is associated with lower levels burnout, HCPs may tools designed enhance their own hopefulness. Several investigators have proposed offering interventions augment hope. We developed an...
Abstract Purpose: Aberrant activation of the B-cell receptor (BCR) is implicated in pathogenesis mature tumors, a concept validated part by clinical success inhibitors BCR-related kinases BTK (Bruton's tyrosine kinase) and PI3Kδ. These have limitations, including paucity complete responses, acquired resistance, toxicity. Here, we examined mechanism which cyclic-AMP/PDE4 signaling axis suppresses PI3K, toward identifying novel mechanism-based combinatorial strategy to attack BCR-dependency...