Nicole R. Fram

ORCID: 0000-0002-7170-8685
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About
Contact & Profiles
Research Areas
  • Intraocular Surgery and Lenses
  • Corneal surgery and disorders
  • Glaucoma and retinal disorders
  • Ophthalmology and Visual Impairment Studies
  • Ocular Infections and Treatments
  • Retinal and Macular Surgery
  • Traumatic Ocular and Foreign Body Injuries
  • Corneal Surgery and Treatments
  • Ocular Surface and Contact Lens
  • Cerebral Venous Sinus Thrombosis
  • Retinal and Optic Conditions
  • Global Healthcare and Medical Tourism
  • Anorectal Disease Treatments and Outcomes
  • Ocular Oncology and Treatments
  • Pituitary Gland Disorders and Treatments
  • Health Systems, Economic Evaluations, Quality of Life
  • Glioma Diagnosis and Treatment
  • Salivary Gland Disorders and Functions
  • Engineering Applied Research
  • Dermatologic Treatments and Research
  • Chronic Myeloid Leukemia Treatments
  • Autoimmune and Inflammatory Disorders
  • Surgical Sutures and Adhesives
  • Ocular Disorders and Treatments
  • Cardiac, Anesthesia and Surgical Outcomes

Armavir Linguistic Social Institution
2023

SUNY Downstate Health Sciences University
2023

American Academy of Ophthalmology
2023

The FRAM Centre
2021-2023

Southern California Eye Institute
2023

Western Texas College
2023

Jones College
2021-2022

Werner-Wicker-Klinik
2021-2022

Doheny Eye Institute
2013-2021

Lee University
2021

Pituitary adenomas result in clinical sequelae and accelerated mortality due to central mass effects or pituitary hormone hypersecretion and/or insufficiency. The low annual incidence prolonged natural history of these rare tumors has hindered efforts evaluate long-term outcomes. Care patients is often provided by larger tertiary specialist referral centers. A novel evidence-based computerized tumor registry was developed systematically epidemiological, biochemical, outcome data....

10.1210/jcem.85.1.6309 article EN The Journal of Clinical Endocrinology & Metabolism 2000-01-01

To evaluate the benefit of various surgical methods to address pseudophakic negative dysphotopsia.Private practice, Los Angeles, California, USA.Interventional case series.The following 4 were used treat dysphotopsia: secondary piggyback intraocular lens (IOL) implantation, reverse optic capture, in-the-bag IOL exchange, and iris suture fixation. Ultrasound biomicroscopy (UBM) was analyze posterior chamber anatomy. The primary outcome partial or complete resolution dysphotopsia symptoms 3...

10.1016/j.jcrs.2011.02.022 article EN Journal of Cataract & Refractive Surgery 2011-06-25

10.1016/j.ophtha.2020.08.009 article EN Ophthalmology 2020-08-12

To evaluate curative and preventative surgical strategies for negative dysphotopsia.Private practice, Los Angeles, California, USA.Retrospective case series.Patients with self-reported chronic dysphotopsia had corrective surgery as the therapeutic group. Second eye surgery, in cases previously operated eye, comprised Chronologically, several were used, including bag-to-bag intraocular lens (IOL) exchange, reducing posterior chamber depth, piggyback secondary IOL placement, bag-to-sulcus...

10.1016/j.jcrs.2017.10.038 article EN other-oa Journal of Cataract & Refractive Surgery 2018-01-01

PurposeThis study was undertaken to evaluate the safety and efficacy of CSF-1 (0.4% pilocarpine hydrochloride ophthalmic solution) for use in individuals with presbyopia.MethodsTwo Phase 3 multicenter, randomized, double-masked, vehicle-controlled, parallel-group clinical trials were conducted 35 private ophthalmology clinics United States from October 2020 February 2022. Key inclusion criteria following: (1) age 45–64 years, (2) distance-corrected near visual acuity (DCNVA) at 40 cm ≥0.40...

10.1016/j.clinthera.2023.12.005 article EN cc-by-nc-nd Clinical Therapeutics 2024-01-11

Negative dysphotopsia is a relatively common photic phenomenon that may occur after implantation of an intraocular lens. The etiology negative not fully understood. In this investigation, optical modeling was developed using nonsequential-component Zemax ray-tracing technology to simulate phenomena experienced by the human eye. simulation investigated effects pupil size, capsulorrhexis and bag diffusiveness. Results demonstrated basis dysphotopsia. We found structures were mainly influenced...

10.1117/1.3656745 article EN Journal of Biomedical Optics 2011-01-01

Purpose To determine the visual outcomes and complications of a new small-incision technique for 4-point fixation hydrophilic acrylic posterior chamber intraocular lens (IOL) in absence capsule support. Setting Three North American tertiary referral centers private practice. Design Retrospective case series. Methods Secondary IOL placement was performed from 2011 to 2014. Indications surgery, clinical results, were analyzed. Primary included postoperative corrected distance acuity (CDVA)...

10.1016/j.jcrs.2015.10.068 article EN Journal of Cataract & Refractive Surgery 2016-02-01

Purpose: To assess the performance of multiple intraocular lens (IOL) formulas in eyes with keratoconus. Methods: Eyes stable keratoconus scheduled for cataract surgery biometry measurements on Lenstar LS900 (Haag-Streit) were included. Prediction errors calculated using 11 different formulas, including two modifiers. Primary outcomes compared standard deviations, mean and median numerical errors, percentage within diopter (D) ranges across all subgroup analysis according to anterior...

10.3928/1081597x-20230124-01 article EN Journal of Refractive Surgery 2023-04-01

To describe the findings of a recently described syndrome, dead bag in which capsular appears to be clear many years postoperatively, becoming diaphanous and floppy unable support intraocular lens (IOL) within it.John A. Moran Eye Center, University Utah, Salt Lake City, Utah.Case series with clinicopathological correlation.Of 10 cases suspected represent 8 IOLs 7 bags were removed because subluxation or dislocation. The available for analysis fixed formalin submitted histopathological...

10.1097/j.jcrs.0000000000000742 article EN Journal of Cataract & Refractive Surgery 2021-07-15

The purposes of this study were to report the indications, graft survival, risk factors for failure, and visual outcomes third or greater penetrating keratoplasties (PKP).Six years Wills Eye Institute Cornea Service charts (2000-2005) retrospectively reviewed identify all patients who had undergone three more PKPs. Graft survival rates by initial diagnosis failure analyzed.Forty-five PKPs identified. total number grafts identified in these 45 was 152, including PKPs, 11 fourth, fifth, two...

10.1097/ico.0b013e3181b31b6f article EN Cornea 2010-02-12

To compare the safety and efficacy of a hydrogel bandage collagen corneal shield in providing wound protection relief pain/discomfort acute period after uneventful unilateral clear phacoemulsification cataract surgery with foldable intraocular lens (IOL) implantation.Seventeen investigational sites United States.Prospective randomized single-masked parallel study.The study comprised patients scheduled to have posterior chamber implantation. The were examined preoperatively frequently for 30...

10.1016/j.jcrs.2010.11.001 article EN Journal of Cataract & Refractive Surgery 2010-12-22

To develop and evaluate a calibrated force gauge designed to simulate the effect of patient-induced manipulation eye with resultant elevation intraocular pressure (IOP) use device determine stability cataract incisions.Three private practice study sites.Clinical trials.A was developed apply controlled quantifiable amounts eye. In 1, used change in IOP during application 1 oz external group healthy volunteers. studies 2 3, assess wound leakage clear corneal incisions that were subjected...

10.1016/j.jcrs.2012.10.046 article EN Journal of Cataract & Refractive Surgery 2013-02-21

Purpose: To evaluate clinical outcomes of intraocular lens (IOL) exchange for intolerable positive dysphotopsia (PD). Setting: Private practice, Advanced Vision Care, Los Angeles, California, USA. Design: Retrospective review, case series. Methods: Fifty-six eyes 46 pseudophakic patients requiring surgical management PD between 2013 and 2019 were reviewed. Thirty-seven had alone 19 combined negative PD. Inclusion criteria: corrected distance visual acuity 20/30 or better without significant...

10.1097/j.jcrs.0000000000000307 article EN Journal of Cataract & Refractive Surgery 2020-07-16

To report the outcomes of intraocular lens (IOL) dislocation management in 6 cases with Retinitis Pigmentosa (RP). Private practice, Los Angeles, USA. Retrospective interventional case series. The medical reports six eyes four RP patients capsule bag fixated posterior chamber IOL were retrospectively reviewed. Pre-operative data included demographics, systemic or ocular disorders, history trauma, previous surgery and pre-operative visual acuity. Outcome measures type surgery, surgical...

10.1016/j.sjopt.2011.09.003 article EN cc-by-nc-nd Saudi Journal of Ophthalmology 2011-10-15

Objective The objective of this study was to assess the performance and reproducibility two currently used ocular surface staining scores in assessment keratoconjunctivitis sicca Sjögren syndrome ( SS ) research classification. Methods In a multidisciplinary clinic for evaluation sicca, we performed all tests American European Consensus Group AECG College Rheumatology ACR )/European League Against Rheumatism EULAR classification criteria, including van Bijsterveld score vBS Ocular Staining...

10.1002/acr2.1033 article EN cc-by-nc-nd ACR Open Rheumatology 2019-06-07

Purpose To determine whether the presence of an ophthalmic viscosurgical device (OVD) in anterior chamber influences intraoperative aberrometry and suggested intraocular lens (IOL) power. Setting Advanced Vision Care, Los Angeles, Specialty Surgery Center, Beverly Hills, California, USA. Design Prospective interventional case series. Method Eyes scheduled for routine phacoemulsification were divided into 6 equal groups, with each having 1 OVDs. After cataract removal, carefully controlled...

10.1016/j.jcrs.2016.04.022 article EN Journal of Cataract & Refractive Surgery 2016-07-01

The safety-basket suture technique is used during surgical management of a malpositioned or subluxated posterior chamber intraocular lens (IOL) in post-vitrectomy eyes. purpose the safety to prevent dislocation IOL repositioning. has been 32 cases date with no occurrence luxation. only complication was transient vitreous hemorrhage 2 This provides increased IOLs and can be for secondary implantation by intrascleral fixation.

10.1016/j.jcrs.2013.08.038 article EN Journal of Cataract & Refractive Surgery 2013-10-23
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