Melissa Grageda

ORCID: 0000-0002-7225-3643
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Research Areas
  • Neonatal Respiratory Health Research
  • Kawasaki Disease and Coronary Complications
  • Child and Adolescent Health
  • COVID-19 Impact on Reproduction
  • Patient Safety and Medication Errors
  • Bacterial Infections and Vaccines
  • Pharmaceutical studies and practices
  • Childhood Cancer Survivors' Quality of Life
  • Respiratory Support and Mechanisms
  • Pharmaceutical Practices and Patient Outcomes
  • Epilepsy research and treatment
  • Sepsis Diagnosis and Treatment
  • Epigenetics and DNA Methylation
  • Metabolism and Genetic Disorders
  • COVID-19 Clinical Research Studies
  • Oral and Craniofacial Lesions
  • Long-Term Effects of COVID-19
  • Cervical Cancer and HPV Research
  • Myofascial pain diagnosis and treatment
  • Fibroblast Growth Factor Research
  • Traumatic Brain Injury Research
  • Peripheral Nerve Disorders
  • Autoimmune Neurological Disorders and Treatments
  • Streptococcal Infections and Treatments
  • Hepatitis Viruses Studies and Epidemiology

Richmond University Medical Center
2015-2021

Pediatrics and Genetics
2020

Research Network (United States)
2020

Pennsylvania State University
2013-2014

Penn State Milton S. Hershey Medical Center
2014

Jamaica Hospital
2013

To describe the clinical manifestations and outcomes of critically ill children with coronavirus disease-19 (COVID-19) in New York City.Retrospective observational study 1 month to 21 years admitted March 14 May 2, 2020, 9 City pediatric intensive care units (PICUs) severe acute respiratory syndrome 2 infection.Of 70 PICUs, median age was 15 (IQR 9, 19) years; 61.4% male; 38.6% Hispanic; 32.9% black; 74.3% comorbidities. Fever (72.9%) cough (71.4%) were common presenting symptoms. Twelve...

10.1016/j.jpeds.2020.07.039 article EN cc-by-nc-sa The Journal of Pediatrics 2020-07-15
Paul L. Aronson Jeffrey P. Louie Ellen Kerns Brittany Jennings Sloane Magee and 95 more Marie E. Wang Nisha Gupta Christopher Kovaleski Lauren M. McDaniel Corrie E. McDaniel Chisom Agbim Owen Amadasun Nicholas Beam Bradley Beamon Heather J. Becker Emma M. Bedard Eric Biondi Jenna Boulet Amelia Bray-Aschenbrenner Rona Brooks Clifford Chen Jacqueline B. Corboy Nickolas Dawlabani Guillermo De Angulo Senayit Demie Jennifer Drexler Nanette C. Dudley Andrew G. Ellis Kelsey Fath Alejandra Frauenfelder Jeff Gill Thomas Graf Melissa Grageda Heidi G. Greening Alison Griffin Amy Groen David Guernsey Sarah Gustafson W. Caleb Hancock Sujit Iyer Patti Jo Jaiyeola A. Jayanth Rebecca Jennings Svetlana S. Kachan‐Liu Aditi Kamat I. Kennedy Loay Khateeb Ohmed Khilji Elizabeth A. Kleweno A. Kumar Stephanie Kwon Alicia La Petra Laeven-Sessions Kaitlyn Phuong Le Rianna C. Leazer Kelly Levasseur Emilee C. Lewis Walid M. Maalouli Bonnie S. Mackenzie Kathleen Mahoney Deborah M. Margulis Lauren Maskin E J McCarty Alexa N. Monroy John M. Morrison Jennifer H. Myszewski Nicole Nadeau Suresh Nagappan Kristen Newcomer Matthew C. Nordstrom Diana Nguyen Peter M. O’Day Yuliya Oumarbaeva Ursula Parlin Summer Peters Mary Jane Piroutek Renee Quarrie Kerrilynn Rice Teresa M. Romano Sahar N. Rooholamini C. Schroeder Elizabeth K. Segar Patrick Seitzinger Suparna Sharma Blair E. Simpson Prachi Singh Yasmine Sobeih Sakina Sojar Karthik K. Srinivasan Emily C. Sterrett Mary Elizabeth Swift-Taylor Sara Szkola Jennifer Thull‐Freedman Irina Topoz Tatyana Vayngortin Christopher Veit Yenimar Ventura-Polanco Ashley Wallace Lindsay Weiss Erika K. Wong

The prevalence of urinary tract infection (UTI), bacteremia, and bacterial meningitis in febrile infants with SARS-CoV-2 is largely unknown. Knowledge the these infections among can inform clinical decision-making. To describe UTI, aged 8 to 60 days vs without SARS-CoV-2. This multicenter cross-sectional study was conducted as part a quality improvement initiative at 106 hospitals US Canada. Participants included full-term, previously healthy, well-appearing bronchiolitis temperature least...

10.1001/jamanetworkopen.2023.13354 article EN cc-by-nc-nd JAMA Network Open 2023-05-12

Knowledge of the methylation profile genes allow for identification biomarkers that may guide diagnosis and effective treatment disease. Human surfactant protein A (SP-A) plays an important role in lung homeostasis immunity, is encoded by two (SFTPA1 SFTPA2). The goal this study was to identify differentially methylated CpG sites promoter region SFTPA2 gene cancer tissue, determine correlation between promoter's expression. For this, we collected 28 pairs cancerous human tissue adjacent...

10.3109/01902148.2014.976298 article EN Experimental Lung Research 2014-12-16

Delayed sequelae from mild traumatic brain injury (Glasgow Coma Score at admission >13, TBI) has been documented in case reports however larger studies of these effects are sparse. We undertook a telephone based survey to assess the long term TBI. tracked 100 pediatric TBI patients via our trauma registry for demographic data including age, severity, and mechanism injury. Then we proceeded contact patient's parents telephone. asked regarding residual symptoms signs concussive Duration out...

10.1177/2333794x20947988 article EN cc-by-nc Global Pediatric Health 2020-01-01

Febrile infection-related epilepsy syndrome (FIRES) is a catastrophic and usually refractory that occurs after febrile illness in previously normal children. The pathogenesis of the unknown, diagnosis typically made by exclusion an exhaustive negative workup for central nervous system infections autoimmune or metabolic disorders. Magnetic resonance imaging patients with this condition has shown hippocampal abnormalities, found several months longer initial seizures. We report healthy...

10.1177/0883073812474100 article EN Journal of Child Neurology 2013-02-11

Background: Kawasaki disease is an acute febrile illness of unknown etiology, characterized by vasculitis medium -sized arteries with a predilection for the coronary arteries. It leading cause acquired heart in childhood 20-25% untreated children developing artery abnormalities. The mainstays therapy are intravenous Immunoglobulin (IVIG) and high dose aspirin to prevent or modify most serious cardiac sequelae. Though rare, immune-mediated hemolysis recognized potentially catastrophic side...

10.1542/peds.142.1_meetingabstract.474 article EN PEDIATRICS 2018-05-01

We report the case of a 7-year old Hispanic boy who presented with acute, severe intermittent diffuse abdominal pain. There was no previous significant medical or surgical history. Physical examination revealed soft abdomen, normoactive bowel sounds, and epigastric tenderness. Initial blood tests imaging were non-contributory, except for focal loops dilated small in mid-abdomen. In less than 24 hours, patient had worsening symptoms physical findings. Emergent laparotomy colonic volvulus...

10.1016/j.epsc.2020.101648 article EN cc-by-nc-nd Journal of Pediatric Surgery Case Reports 2020-09-13

1. Thuthu Aung, MD* 2. Neha Ahuja, MD* 3. Joan Graziano, MD* 4. Melissa Grageda, MD* 1. *Department of Pediatrics, Richmond University Medical Center, Staten Island, NY A 16-year-old girl presents to the psychiatric emergency department with acute worsening aggression, auditory hallucinations, and suicidal thoughts for past 10 days. Her medical history is significant a resected right ovarian teratoma 7 years earlier. Due escalating combativeness in department, psychiatrist administers...

10.1542/pir.2015-0100 article EN Pediatrics in Review 2017-10-01

Introductory Statement: Approximately 1 in 10 children is classified as having current asthma. 50% have poorly controlled disease, resulting 61% visiting an emergency department or urgent care clinic. 5% of all pediatric admissions are asthma-related. Poor control asthma partly the result a gap that exists between recommended and actual provided. In our community, there lack education support organizations for patients, despite high incidence. Implementation family-centered,...

10.1542/peds.141.1_meetingabstract.102 article EN 2018-01-01

Introductory Statement: Preventing adverse drug events (ADE) is of paramount priority in health care practice. In 2014, there were 1,289,133 reported the United States. Pediatric event rates are significant at 5.7 to 11% inpatient setting. Moreover, 2 5% ADE preventable. Medication reconciliation a …

10.1542/peds.141.1_meetingabstract.104 article EN 2018-01-01

Introductory Statement: Complete vaccination against the human papilloma virus (HPV) is safe and effective in reducing rate of cervical cancers genital warts. According to National Immunization Survey (NIS) 2013, only 37.6% girls 6.8 % boys between 13-17 years received 3 recommended doses HPV vaccine. Aim Study: • To …

10.1542/peds.141.1_meetingabstract.137 article EN 2018-01-01

Aim statement: To decrease the rate of invalid newborn screening samples to < 4.0% by 6 months post-intervention. Background: Each year, millions newborns across United States are routinely screened via (NBS) programs for genetic and metabolic conditions. Such conditions may have serious, even fatal consequences, especially if diagnosis is delayed. Submission contribute delayed treatment, as well incur additional costs cause parental anxiety. In our region, NBS sample 4.7%. Objectives: rates …

10.1542/peds.142.1_meetingabstract.388 article EN PEDIATRICS 2018-05-01

Background: About four in ten refugees entering the US each year are young children and adolescents (Fig 1). These may have experienced disrupted early lives, high violence exposure further adverse experiences settlement countries. 80 to 90% of refugee been exposed harsh conditions, including long-term hunger violence. Such hardships initiate a trajectory that puts at increased risk malnutrition chronic health problems after resettlement. Moreover, immigrant more likely live below federal...

10.1542/peds.146.1_meetingabstract.573 article EN PEDIATRICS 2020-07-01
Mehmet Nevzat Çizmeci Floris Groenendaal Kian D. Liem Ingrid Van Haastert Isabel Benavente-Fern Andez and 95 more H. v. Straaten Sylke J. Steggerda Bert J. Smit Andrew Whitelaw Peter A. Woerdeman Axel Heep Linda de Vries Seetha Shankaran Monika Bajaj Girija Natarajan Somnath Saha Athina Pappas Alexis S. Davis Susan R. Hintz Ira Adams‐Chapman Abhik Das Edward F. Bell Barbara J. Stoll Michele Walsh Abbot R. Laptook Waldemar A. Carlo Krisa P. Van Meurs Pablo Anchez M. Bethany Ball Ellen C. Hale Joseph Abrams Shana Godfred‐Cato Matthew E. Oster Eric J. Chow Kim R. Derespina Shubhi Kaushik Anna Plichta E. J. Conway Asher Bercow Jaeun Choi Ruth Eisenberg Jennifer Gillen Anita Sen Claire Hennigan Lillian M. Zerihun Sule Doymaz Michael Keenaghan Stephanie Jarrin Franscene Oulds Manoj Gupta Louisdon Pierre Melissa Grageda H. Michael Ushay Vinay Nadkarni Stephanie Popofsky Asif Noor Jill Leavens-Maurer Maria Lyn Quintos-Alagheband Ann Mock Alexandra Vinci Eileen Magri Meredith Akerman Estela Noyola Mona Do Billy Rigaud Jennifer Pak Adam Lighter Nazeeh Ratner Leonard Hanna Barbara Dietrick Eleanor J. Molloy An N. Massaro Tammy Strickland Jie Zhu Marie Slevin Veronica Donoghue Deirdre Sweetman Lynne Kelly Mary O’Dea Meaghan McGowan Gilbert Vézina Penny Glass Dhananjay Vaidya M Guillot Ting Guo Steven Ufkes J Schneider Anne Synnes Tetsuya Isayama Daria O’Reilly Joseph Beyene Prakesh S. Shah Shoo Lee Sarah McDonald Hidenori Kawasaki Takahiro Yamada Yoshimitsu Takahashi Takeo Nakayama Takahito Wada Liisa Lehtonen

10.1016/s0022-3476(20)31188-4 article EN The Journal of Pediatrics 2020-10-22
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