A5101491994- Reproductive Biology and Fertility
- Ovarian function and disorders
- Advanced Differential Geometry Research
- Relativity and Gravitational Theory
- COVID-19 Clinical Research Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Reproductive System and Pregnancy
- Hormonal and reproductive studies
- Tracheal and airway disorders
- Lipid metabolism and biosynthesis
- Cosmology and Gravitation Theories
- Neonatal Respiratory Health Research
- Growth Hormone and Insulin-like Growth Factors
- Pediatric health and respiratory diseases
- Reproductive Physiology in Livestock
- Autoimmune and Inflammatory Disorders Research
- Pulsars and Gravitational Waves Research
- Respiratory viral infections research
Shandong Provincial Hospital
2024
Shandong University
2024
Shenzhen Institutes of Advanced Technology
2016-2021
Chinese Academy of Sciences
2013-2021
University of Chinese Academy of Sciences
2018-2019
University of Science and Technology of China
2013
Chemerin, a chemokine, plays important roles in immune responses, inflammation, adipogenesis, and carbohydrate metabolism. Our recent research has shown that chemerin an inhibitory effect on hormone secretion from the testis ovary. However, whether G protein-coupled receptor 1 (GPR1), active for chemerin, regulates steroidogenesis luteolysis corpus luteum is still unknown. In this study, we established pregnant mare serum gonadotropin-human chorionic gonadotropin (PMSG-hCG) superovulation...
Polycystic ovary syndrome (PCOS) is a complex genetic disease with multifarious phenotypes. Many researches use dehydroepiandrosterone (DHEA) to induce PCOS in pubertal mouse models. The aim of this study was investigate the role GPR1 (DHEA)-induced hyperandrogenized mice. Prepubertal C57BL/6 mice (25 days age) and Gpr1-deficient were each divided into two groups injected daily sesame oil or without DHEA (6 mg/100 g) for 21 consecutive days. Hematoxylin eosin (H&E) staining performed...
Hyperandrogenism is a key pathological feature of polycystic ovarian syndrome (PCOS). Excess androgen can lead to PCOS-like cell hypertrophy in the ovaries and adipose tissue rodents. Here, we established dihydrotestosterone (DHT)-induced hyperandrogenic mouse model analyze differences gene expression signaling pathways gonad fat pads mice treated with or without DHT by RNA microarray analysis. From results, focused on overlapping differentially expressed gene— Col6a5 —and major enriched...
Under consideration of coordinate conditions, we get the Schwarzschild-Beltrami-de Sitter (S-BdS) metric solution Einstein field equations with a cosmological constant $\Lambda$. A brief review to de invariant special relativity (dS-SR), and general (dS-GR, or GR $\Lambda$) is presented. The Beltrami $B_{\mu\nu}$ provides inertial reference frame for dS-spacetime. By examining Schwarzschild-de (S-dS) $g_{\mu\nu}^{(M)}$ existed in literatures since 1918, find that S-dS describes some mixing...
Polycystic ovary syndrome (PCOS) is an endocrine disorder with a high prevalence in women of childbearing age. To date, there no method efficiently diagnosing PCOS and curing it completely because its pathomechanism remains unclear. Here, we investigated whether metabolic abnormalities maintain the hyperandrogenism PCOS-like ovaries symptoms induced by excess androgen are treatable. We ceased abnormal dihydrotestosterone (DHT) stimulation to determine changes mice. After ceasing DHT...
Abstract Background This study investigates the clinical characteristics and outcomes of pediatric patients with rheumatic diseases infected COVID-19 in China. Methods We conducted a retrospective analysis who contracted COVID-19. Data were collected via comprehensive questionnaire 14-day follow-up. Multivariable logistic regression was used to assess severe outcomes, network analyses evaluated symptom correlations. Results A total 1070 cases collected. Fever (88.05%) cough (62.75%) most...