- Neuroscience of respiration and sleep
- Cardiovascular Function and Risk Factors
- Obstructive Sleep Apnea Research
- Advanced Neuroimaging Techniques and Applications
- Cardiac Valve Diseases and Treatments
- Functional Brain Connectivity Studies
- Cardiovascular Effects of Exercise
- Cardiac Structural Anomalies and Repair
- Sleep and Wakefulness Research
- Cardiomyopathy and Myosin Studies
- Cell Adhesion Molecules Research
- Colorectal Cancer Treatments and Studies
- Cancer Immunotherapy and Biomarkers
- Radiation Therapy and Dosimetry
- Neonatal and fetal brain pathology
- Colorectal and Anal Carcinomas
- Cancer, Hypoxia, and Metabolism
- Sarcoma Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Cancer Cells and Metastasis
- Dysphagia Assessment and Management
- Eosinophilic Disorders and Syndromes
- Peroxisome Proliferator-Activated Receptors
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cardiovascular and Diving-Related Complications
Nanchang University
2019-2024
First Affiliated Hospital of Nanchang University
2019-2022
Nanjing University of Chinese Medicine
2020-2022
Second Affiliated Hospital of Nanchang University
2022
Capital Medical University
2020-2021
Beijing Anzhen Hospital
2020-2021
Beijing Chaoyang Emergency Medical Center
2021
Wuxi Taihu Hospital
2017
Background: The amygdala is one of the core areas emotional circuits. Previous neuroimaging studies have revealed that patients with obstructive sleep apnea (OSA) aberrant structure and function in several brain (including amygdala). However, resting-state functional connectivity (rs-FC) amgydala subregions remains uncertain. Objective: To determine whether rs-FC exists between other such abnormalities are related to disorders cognitive impairment OSA. Methods: magnetic resonance imaging...
The triglyceride-glucose index is a valuable marker of insulin resistance. However, the predictive value this for postoperative atrial fibrillation in patients undergoing septal myectomy remains unclear. A total 409 with hypertrophic obstructive cardiomyopathy who underwent were recruited study. was calculated all preoperatively. All clinical data collection, blood sampling, and standard echocardiographic examinations during hospitalization. prevalence approximately 15% present Multivariate...
Introduction: Continuous positive airway pressure (CPAP) therapy improves clinical symptoms in patients with obstructive sleep apnea (OSA); however, the mechanism of this improvement and how it may be associated restoration white matter (WM) structures brain is unclear. Therefore, study investigated relationship between structural recovery WM improvements cognitive function emotion after long-term (12 months) CPAP treatment OSA. Methods: We collected data from 17 OSA before 12 months...
White matter (WM) fiber alterations in patients with obstructive sleep apnea (OSA) is associated cognitive impairment, which can be alleviated by continuous positive airway pressure (CPAP). In this study, we aimed to investigate the changes WM OSA at baseline (pre-CPAP) and 3 months after CPAP adherence treatment (post-CPAP), provide a basis for understanding reversible alteration disease. Magnetic resonance imaging (MRI) was performed on 20 severely untreated good sleepers. Tract-based...
Obstructive sleep apnea (OSA) is the most common disorder worldwide. Previous studies have shown that OSA patients are often accompanied by cognitive function loss, and underlying neurophysiological mechanism still unclear. This study aimed to determine whether there differences in regional homogeneity (Reho) functional connectivity (FC) across brain between with MCI (OSA-MCI) those without (OSA-nMCI) such can be used distinguish two groups. Resting state magnetic resonance data were...
Activation of the vitronectin receptor αvβ3 and phosphorylation extracellular signal‑regulated kinase (ERK)1/2 are critical events during tumor development progression. The aim present study was to investigate effects WD‑3, a formula used in traditional Chinese medicine, on integrin ERK1/2 expression vivo using nude mouse‑human gastric cancer xenograft model combined with non‑invasive, real‑time 18F‑Arg‑Gly‑Asp (RGD) positron emission tomography (PET)/computerized (CT) imaging methods....
In this study, we aimed to use voxel-level degree centrality (DC) features in combination with machine learning methods distinguish obstructive sleep apnea (OSA) patients and without mild cognitive impairment (MCI). Ninety-nine OSA were recruited for rs-MRI scanning, including 51 MCI 48 participants no impairment. Based on the Automated Anatomical Labeling (AAL) brain atlas, DC of all calculated extracted. Ten screened out by deleting variables high pin-correlation minimum absolute...
Background: The incidence of obstructive sleep apnea (OSA) is significantly higher in patients who undergo coronary artery bypass grafting (CABG). OSA correlated with a postoperative complications undergoing CABG. However, whether associated decrease renal function and dialysis after CABG remains unclear.
Hypertrophic cardiomyopathy (HCM) with extreme interventricular septal thickness (IVST) is associated a higher incidence of adverse cardiovascular events. However, the results these patients who underwent myectomy are unclear.We studied 47 HCM IVST ≥30 mm between 2011 and 2018 in Anzhen Hospital. After 2:1 propensity score matching, study cohort included 141 94 <30 mm.Patients had longer clinical course disease, high syncope, palpitation, moderate or severe mitral regurgitation. mean...
Obstructive sleep apnea (OSA) is associated with a higher prevalence of postoperative atrial fibrillation in patients who underwent cardiac surgery. However, whether OSA risk factor for after septal myectomy remains unclear. We hypothesized that was myectomy.A total 99 hypertrophic obstructive cardiomyopathy were included our manuscript. Polysomnography performed all patients, and the heart rhythm continuously monitored during perioperative period.In present study, 25 (25.3%) developed...
Number 3 Prescription (WD-3) is an herbal remedy used in traditional Chinese medicine that has been shown to improve the outcomes of patients with advanced colon and gastric cancers. This study aimed investigate effect WD-3 on proliferation, glycolysis, hexokinase 2 expression breast cancer cells. Four cell lines (MDA-MB-231, BT-549, MCF-7, MCF-7/ADR-RES) were treated different concentrations compared blank control (phosphate-buffered saline). Each was also divided into WD-3, paclitaxel,...