A5003918874- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
- Family and Disability Support Research
- Child Development and Digital Technology
- Virology and Viral Diseases
- Genomics and Rare Diseases
- Metabolism and Genetic Disorders
- Epilepsy research and treatment
- Child Nutrition and Feeding Issues
- Genomics and Phylogenetic Studies
- Intergenerational Family Dynamics and Caregiving
- Phytochemicals and Antioxidant Activities
- Molecular Biology Techniques and Applications
- Plant Diversity and Evolution
- Retinoids in leukemia and cellular processes
- Child and Adolescent Psychosocial and Emotional Development
- Healthcare professionals’ stress and burnout
- Air Quality and Health Impacts
- Arsenic contamination and mitigation
- Attention Deficit Hyperactivity Disorder
- Forensic and Genetic Research
- Genomic variations and chromosomal abnormalities
- Genomics and Chromatin Dynamics
- Thyroid Disorders and Treatments
- Energy and Environment Impacts
Huazhong University of Science and Technology
2024-2025
Guizhou University
2017-2024
Guizhou Provincial People's Hospital
2015-2024
Children's Hospital of Fudan University
2015-2024
Guiyang Medical University
2016-2024
Institute of Chemical Industry of Forest Products
2024
Shanghai Children's Medical Center
2023-2024
Shanghai Jiao Tong University
2024
Zunyi Medical University
2023
Twelfth Guangzhou City People's Hospital
2020
Abstract Background China is becoming an aging society at the fastest pace in history, and there are a large number of empty nesters country. With economic social development, internal support systems among families gradually weakening. Supporting elderly thus emerging as significant issue, promoting digital health technologies effective way to help address it. Encouraging application Internet care use important means technologies. This paper examines current state by factors influencing it...
This study investigates the pivotal role of withering in shaping quality white tea. We used a single-factor experimental design to optimize both light and intensity during process. Using gas chromatography-mass spectrometry (GC-MS), sensory evaluation, physical chemical analyses, we identified ideal parameters as yellow at an 5000 lx. Subsequently, non-targeted metabolomics transcriptomics analyze mechanism tea formation various stages withering. The results showed significant changes...
Abstract Background Red raspberry ( Rubus idaeus L.) is a renowned fruit plant with significant medicinal value. Its nuclear genome and chloroplast (plastome) have been reported, while there lack of genetic information on its mitogenome. We sequenced assembled the complete mitogenome R. , conducted series investigations comparing it genomes, so as to better gain comprehensive understanding species’ background. Results The represented by one circular chromosome 438,947 bp. Twenty-four core...
There is still no comprehensive description of the general population regarding clinical features and genetic etiology for co-occurring epilepsy autism spectrum disorder (ASD) in Chinese children. This study was a retrospective children diagnosed with ASD from January 1st, 2015, to May 2018, at Children's Hospital Fudan University. A total 117 patients met inclusion criteria, 103 subjects were eligible. Among them, 88 underwent testing, 47 (53.4%) identified as having pathogenic or likely...
Objectives: To investigate the association between ambient air pollutant exposure and daily hospital admissions for respiratory diseases in children Guiyang. Methods: Clinical data of pediatric inpatients with disease from 2009 to 2016 Guizhou Provincial People’s Hospital PM2.5, NO2, PM10 SO2 concentration were retrieved. A canonical correlation analysis (CCA) was applied analyse pollutants diseases. reproducibility pollution duration direct cost hospitalization. The support vector...
Willingness to receive eldercare is an important factor affecting the reasonable allocation of resources and appropriate development services. This study aimed investigate differences in willingness influencing factors urban rural areas.Cross-sectional survey.Research was conducted areas three cities (Harbin, Qiqihar Jiamusi) Heilongjiang province, China.A total 1003 elderly were selected through multistage sampling including 581 422 areas.Descriptive statistics reported for socioeconomic...
The purpose of this study was to explore the psychometric properties Chinese version autism spectrum rating scale (ASRS). We recruited 1,625 community-based children and 211 disorder (ASD) cases from 4 sites, parents all participants completed ASRS. A robust weighted least squares means variance adjusted estimator used for exploratory factor analysis. 3-factor structure included 59 items suitable current sample. item reliability modified ASRS (MC-ASRS) excellent. Moreover, with 60 as cut-off...
The reported prevalence of autism spectrum disorder (ASD) has been increasing rapidly in many parts the world. However, data on its China are largely missing. Here, we assessed suitability modified Chinese version a newly-developed ASD screening tool, Modified Autism Spectrum Rating Scales (MC-ASRS) for children aged 6-12 years, through comparison with Social Responsiveness Scale (SRS) that widely used screening. We recruited parents/caregivers 1588 typically-developing and 190 years to...
Background: Autism spectrum disorder (ASD) is a group of early-onset neurodevelopmental disorders. However, there no valuable biomarker for the early diagnosis ASD. Our large-scale and multi-center study aims to identify metabolic variations between ASD healthy children investigate differential metabolites associated pathogenic mechanisms. Methods: One hundred seventeen autistic 119 were recruited from research centers 7 cities. Urine samples assayed by 1 H-NMR metabolomics analysis detect...
Objective: To evaluate the levels of awareness and knowledge ASD among child health care workers in China, we conducted a cross-sectional, questionnaire-based study to assess participants' ASD. Methods: A total 159 from Southwest China participated survey filled out questionnaire.Descriptive analysis was on five parts questionnaire, including general knowledge, symptomology, screening diagnosis, intervention treatment. Univariate used impacts basic demographic characteristics questionnaire...
Subarachnoid hemorrhage (SAH) is a cerebrovascular disease associated with high morbidity and mortality. CXCR4 provides neuroprotective effects, which can alleviate brain injury inflammation induced by stroke. Previous studies have suggested that reduces the pyroptosis of LPS‐stimulated BV2 cells. The purpose this study was to evaluate antipyroptosis effects mechanisms after SAH. SAH animal model via endovascular perforation. A total 136 male Sprague‐Dawley rats were used. Recombinant human...
Abstract Aims Status epilepticus (SE) is the most common neurological emergency in pediatric patients. This study aimed to screen for prognostic biomarkers of SE cerebrospinal fluid (CSF) using metabolomics. Methods Ultra‐performance liquid chromatography quadrupole time‐of‐flight tandem mass spectrometry (UPLC‐QTOF‐MS) was conducted identify CSF metabolomics by comparing poor outcome group ( N = 13) with good 15) children SE. Differentially expressed metabolites were identified Mann–Whitney...
This study aimed to establish norms for the modified Chinese version of Autism Spectrum Rating Scale (ASRS). Participants were recruited from Shanghai, Harbin, Guangzhou, and Changsha, China, their parents teachers invited complete Parent Teacher ASRS. In both versions, boys had significantly higher sub-scale scores total score (T-score) by 1-3 4-5 points respectively, than girls (both P < 0.001). Age weak correlations with some sub-scores T-score (r ranged -0.1859 0.0738), reached...
Abstract Background The mental health and quality of life in children with asthma have attracted widespread attention. This study focused on the evaluation conditions their clinical characteristics Chinese asthma. Methods A total 261 aged 6 to 16 years old age- gender-matched from general population were recruited participate this Guizhou Provincial People’s Hospital. parents all subjects interviewed using MINI Kid required finish a questionnaire. Logistic regression analysis was performed...