A5005717177- Insect Utilization and Effects
- Adipokines, Inflammation, and Metabolic Diseases
- Bone health and treatments
- Pharmacological Effects of Natural Compounds
- Adipose Tissue and Metabolism
- Biochemical effects in animals
- Bone Metabolism and Diseases
- Bone health and osteoporosis research
- Liver Disease Diagnosis and Treatment
- Protein Hydrolysis and Bioactive Peptides
- Antimicrobial Peptides and Activities
- Muscle Physiology and Disorders
- Bioactive natural compounds
- Food Quality and Safety Studies
- Insect and Arachnid Ecology and Behavior
- Phytochemistry and biological activity of medicinal plants
- Phytochemicals and Antioxidant Activities
- Pharmacology and Obesity Treatment
- Invertebrate Immune Response Mechanisms
- Muscle metabolism and nutrition
- Lichen and fungal ecology
- Metabolism, Diabetes, and Cancer
- Phytoestrogen effects and research
- Traditional Chinese Medicine Analysis
- Nutrition, Genetics, and Disease
Rural Development Administration
2021-2024
Instituto de Ciencias Agrarias
2024
National Institute of Agricultural Science and Technology
2023
Sunchon National University
2014-2020
Suncheon Jeil College
2016
This study examined the effects of syringic acid (SA) on obese diet-induced hepatic dysfunction.
This study investigated the mechanism of processed tomato vinegar beverage (TVB)-mediated anti-obesity and anti-insulin resistance effects in high-fat diet (HF)-induced obese mice. Oral administration TVB (14 mL kg−1 body weight) to HF-fed mice for 6 weeks effectively reduced visceral fat weight significantly lowered plasma free fatty acid, triglyceride hepatic levels. increased fecal excretion, both phosphorylated AMP-activated protein kinase (AMPK) acetyl-CoA carboxylase (ACC) peroxisome...
Scopoletin is a bioactive component in many edible plants and fruits. This study investigated the effects of scopoletin on hepatic steatosis inflammation high‐fat diet fed type 1 diabetic mice by comparison with metformin. (0.01%, w/w) or metformin (0.5%, was provided to streptozotocin‐induced for 11 weeks. Both lowered blood glucose HbA 1c , serum ALT, TNF‐α IL‐6 levels, intolerance, lipid accumulation compared control group. down‐regulated gene expression triglyceride ( Pparg Plpp2 Dgat2 )...
This study examined the effects of defatted mealworm fermentation extract (MWF) on alcoholic liver injury in rats. The rats were fed either a Lieber-DeCarli control (Con) or alcohol liquid diet (EtOH). alcohol-fed administered MWF (50, 100, 200 mg/kg/day) and silymarin (200 orally for eight weeks. prevented alcohol-induced hepatocellular damage by decreasing their serum aspartate transaminase, alanine gamma-glutamyl transpeptidase levels significantly compared to EtOH group. effectively...
Chitin is mostly produced from crustaceans, but it difficult to supply raw materials due marine pollution, and the commonly used chemical chitin extraction method not environmentally friendly. Therefore, this study aims establish a process using enzymes develop edible insect-derived as an eco-friendly new material. The response surface methodology (RSM) was determine optimal conditions for enzymatic hydrolysis. hydrolysis by RSM were determined be substrate concentration (7.5%), enzyme (80...
Modulation of osteoclast formation could be a therapeutic target for inhibiting pathological bone destruction. The receptor activator nuclear factor (NF)-κB ligand (RANKL) is known to an essential in differentiation and activation inducers. However, whether Protaetia brevitarsis seulensis (P. brevitarsis) larvae-a traditional animal-derived medicine used many Asian countries-can inhibit RANKL-induced prevent ovariectomy (OVX)-induced loss has not been evaluated. Here, we aimed investigate...
This study investigated the anti-sarcopenic effect of fermented Tenebrio molitor larvae (mealworms) extract (FME) in both dexamethasone (DEX)-treated C2C12 cells and mice. FME (100 µg/mL) increased diameter myotubes inhibited gene protein expression atrogin-1 compared to DEX- or non-fermented mealworms (ME)-treated cells. Male C57BL/6N mice were divided into five groups: Normal Control (NC), DEX (10 mg/kg, intraperitoneal), three groups DEX+FME (100, 200, 500 mg FME/kg/day, oral) for two...
This study evaluated whether bergapten and methoxsalen could prevent diabetes-induced osteoporosis its underlying mechanism. For 10 weeks, or (0.02%, w/w) was applied to diabetic mice that were provided with a high-fat diet streptozotocin. Bone mineral density (BMD) microarchitecture quality significantly reduced in the control group; however, both reversed serum osteocalcin, bone-alkaline phosphatase femur BMD. These coumarin derivatives increased bone volume trabecular number, whereas they...
We have previously showed that defatted mealworm fermentation extract (MWF) attenuates alcoholic liver injury by regulating lipid, inflammatory, and antioxidant metabolism in chronic alcohol-fed rats. The current metabolomics study was performed to monitor biochemical events following the administration of MWF (daily for eight weeks) a rat model gas chromatography-tandem mass spectrometry (GC-MS/MS). levels 15 amino acids (AAs), 17 organic (OAs), 19 free fatty (FFAs) were measured serum....
Mealworms (Tenebrio molitor larva) are an edible insect and a protein-rich food; however, research on mealworms as substitute protein is insufficient. In this study, mealworm fermentation extract (TMP) was assessed replacement for soy (SP) in control diet (CON) or high-fat (HFD) of mice 12 weeks. TMP substitution reduced body weight, weight gain, fat mass (perirenal mesenteric), size, glucose intolerance, insulin resistance compared to the HFD-SP group. alleviated hepatic steatosis (lipid...
(OC) is a well-known edible insect. Several researches on the health benefits of OC consumption have been performed to date; however, their effect eye remains largely unknown. This study aimed assess protective effects extracts oxidative stress retinal pigment epithelium (RPE) cells. Oxidative damage has identified as one key regulatory factors in age-related macular degeneration. H
The increasing global population and the environmental consequences of meat consumption have led to exploration alternative sources protein. Edible insects gained attention as a sustainable nutritionally rich alternative. We investigated effects two commonly consumed insects, Protaetia brevitarsis seulensis larva Bombyx mori pupa, on beneficial gut microbiota growth, using whole 16s metagenome sequencing assess diet-associated changes. Seven-week-old female C57BL/6J mice were administered...
Aging, and other disease-related muscle disorders are serious health problems. Dexamethasone (DEX), a synthetic glucocorticoid, can trigger skeletal atrophy. This study examined the effects of mealworm (Tenebrio molitor larva) ethanol extract (TME) on C2C12 myoblast differentiation DEX-induced myotube TME induced formation compared to medium (DM) group. also significantly increased mRNA expression creatine kinase (CKm) myogenic regulatory factors (MRFs), such as myogenin (MyoG), factor...
Previous studies found that mealworm fermentation extract (TMP) reduced alcoholic hepatic steatogenesis. This study examined how the ratio of TMP and soy protein (SP) mix affected glucose lipid metabolism in obese mice given a high-fat diet (HFD). Mice were HFD supplemented with 100% SP or following three ratios for 12 weeks: 20% (S4T1), 40% (S3T2), 60% (S2T3) TMP. When compared to group, S2T3 group had considerably lower body weight gain food consumption. slightly blood insulin leptin...
Thamnolia vermicularis (TV) is an edible lichen that prevalent in the alpine zone of East Asia. This study evaluated feasibility using TV acetone extracts as a functional food based on experiments cell line and obese mice. The cellular triglyceride levels Oil red O staining 3T3-L1 cells indicated (5 10 μg/mL) dose-dependently suppressed adipocyte differentiation lipid accumulation compared with control. extract (0.4%, w/w) high-fat diet (HFD) was supplemented to C57BL/6N mice for 12 weeks,...
The purpose of the present study was to determine whether an anti-obesity effect a Polygonum multiflorum Thunb. hot water extract (PW) involved in lipid metabolism white adipose tissue (WAT) and brown (BAT) high-fat diet (HFD)-induced C57BL/6N obese mice. Mice freely received normal (NCD) or HFD for 12 weeks; HFD-fed mice were orally given PW (100 300 mg/kg) garcinia cambogia (GC, 200 once day. After weeks, (300 GC significantly alleviated adiposity by reducing body weight, WAT weights, food...
This study investigated the effects and mechanism of Heshouwu (Polygonum multiflorum Thunb.) water extract (HSW) on diabetes-related bone loss in mice. HSW was orally administered (300 mg/kg body weight) to high-fat diet streptozotocin-induced diabetic mice for 10 weeks. significantly alleviated mouse weight hyperglycemia compared with control group, elevated serum levels insulin, osteocalcin, bone-alkaline phosphatase. supplementation also increased volume/tissue volume ratio trabecular...