A5026730450- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- HIV-related health complications and treatments
- Cardiac Arrhythmias and Treatments
- HIV, Drug Use, Sexual Risk
- Cervical Cancer and HPV Research
- HIV Research and Treatment
- Colorectal and Anal Carcinomas
- Cardiac, Anesthesia and Surgical Outcomes
- Genital Health and Disease
- Adolescent Sexual and Reproductive Health
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Syphilis Diagnosis and Treatment
- Cardiac pacing and defibrillation studies
- Reproductive Health and Technologies
- Advances in Oncology and Radiotherapy
- Influenza Virus Research Studies
- Herpesvirus Infections and Treatments
- Contact Dermatitis and Allergies
- SARS-CoV-2 and COVID-19 Research
- Sex work and related issues
- COVID-19 Clinical Research Studies
- ECG Monitoring and Analysis
- COVID-19 and healthcare impacts
The University of Sydney
2015-2024
Keck Hospital of USC
2024
Royal College of Surgeons in Ireland
2023
Lakeland Regional Medical Center
2021
Regional Health
2021
Nemours Children's Health System
2021
Northern Health and Social Care Trust
2021
Monklands Hospital
2021
Public Health England
2021
University of Tennessee Health Science Center
2020
Background Atrial fibrillation is associated with higher mortality. Identification of causes death and contemporary risk factors for all‐cause mortality may guide interventions. Methods Results In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared Vitamin K Antagonism Prevention Stroke Embolism Trial in Fibrillation (ROCKET AF) study, patients nonvalvular atrial were randomized to rivaroxaban or dose‐adjusted warfarin. Cox proportional hazards regression backward...
This study used a recent national population survey on childhood and adolescent non-fatal injuries to investigate the effects of recall bias estimating annual injury rates. Strategies adjust for are recommended.The 1988 Child Health Supplement National Interview Survey collected 12-month information that occurred sample 17,110 children aged 0 through 17 years. Using timing interviews reported injuries, estimated rates were calculated 12 accumulative periods (from 1 months).The data show...
Remdesivir is a novel therapeutic with known activity against SARS CoV-2 and related coronaviruses. Remdesivir, as well convalescent plasma therapy, are currently under investigation potential therapies for patients Coronavirus Disease 19 (COVID-19). In this case report we summarize the use of therapy then remdesivir late addition in treatment critically ill obstetric patient COVID-19. The subsequently improved, was extubated 5 days after initiation remdesivir, transitioned to room air 24 h...
To observe the prevalence of lumbar intervertebral disc degeneration in elite athletes as compared with published literature changes seen non-athletes-that is, normal population.The spines 31 Olympic who presented to Polyclinic low back pain and/or sciatica were examined using magnetic resonance imaging. Three criteria looked at: (a) loss signal intensity; (b) height; (c) presence displacement. The results then recorded and correlated levels.The intensity was progressively reduced more...
To determine the importance of angiotensin converting enzyme (ACE) activity in development arterial proliferative lesions a primate model, response to vascular injury was studied five baboons treated with oral cilazapril (20 mg/kg/day) and untreated control animals. Each animal underwent three procedures: 1) carotid artery endarterectomy, 2) balloon catheter deendothelialization superficial femoral artery, 3) surgical placement bilateral aorto-iliac expanded polytetrafluoroethylene...
Summary Eighty patients with aorto-iliac / femoro-popliteal atherosclerosis were collected to examine in detail their plasma cholesteryl ester fatty acid compositions and compare them the incidence of ischaemic heart disease through a 4-year follow-up. Various other biochemical rheological parameters also measured see if these might explain any association between abnormal pattern disease. The was specifically generally similar that found essential (EFA) deficient animals children as shown...
Objective: To evaluate the impact and cost-effectiveness of needle-syringe programs (NSPs) with respect to HIV hepatitis C virus (HCV) infections among Australian injecting drug users (IDUs). Design/methods: A health economic analysis was conducted incorporating a mathematical model HCV transmission IDUs. An empirical relationship between syringe availability receptive sharing (RSS) assessed. We compared epidemiological outcomes costs NSP coverage (status quo RSS 15–17%) scenarios that had...
This study was undertaken to assess whether the prevalence of lower genital tract infections among human immunodeficiency virus (HIV)—seropositive women higher than high-risk HIV-seronegative at their baseline visit for HIV Epidemiology Research Study. Results were available 851 HIV-seropositive and 434 women. Human papilloma (HPV) infection more prevalent (64% vs. 28%). Bacterial vaginosis common (35% 33%), followed by trichomoniasis (12% 10%), syphilis (8% 6%), Chlamydia trachomatis (4%...
<h3>Objectives</h3> Australian guidelines recommend annual testing for HIV and sexually transmitted infections (STIs) all men who have sex with (MSM) 3–6 monthly those at higher risk as defined by behavioural criteria. We assessed HIV/STI re-testing rates among MSM attending primary care clinics. <h3>Methods</h3> conducted a retrospective follow-up of negative tested or STIs (chlamydia syphilis) four clinics in the 9-month period: April to December 2006. Re-testing these were calculated over...
The objective of this study was to determine levels experience and knowledge concerning anal dysplasia, Pap smear tests, human papillomavirus (HPV) among gay other homosexually active men.Three hundred eighty-four men attending a large community event in Melbourne completed short survey.Ninety-two percent identified as 4.8% bisexual. A total 6.4% were HIV-positive further 3.5% did not know their HIV status. On range measures, it clear that the knew very little about cancer (19% scored zero...
Objective To estimate the rate of combination antiretroviral treatment change and factors associated with among patients recruited in Australian HIV Observational Database (AHOD). Methods Analyses were based on AHOD who had commenced after 1 January 1997. Combination was defined as addition or at least one drug. A random‐effect Poisson regression model used to assess increased rates change. Results total 596 included analysis, a median follow‐up 2.3 years. The overall this group 0.45...
Abstract Aims: Allopurinol hypersensitivity (AH) can rarely be manifest as Stevens–Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) that have high mortality rates. Less serious, but still significant, skin and systemic reactions form part of the AH spectrum. One hundred per cent Han Chinese with SJS/TEN due to allopurinol been found at least heterozygous for HLA‐B*5801, carriage rate this allele in population being about 15%. The association has weaker Caucasians whose HLA‐B*5801...
Journal Article Systemic Sporotrichosis Treated with Itraconazole Get access Richard E. Winn, Winn From the Department of Medicine, Fitzsimons Army Medical Center, Aurora, Colorado; North Colorado Greeley, David Grant Travis Air Force Base, California; and Infectious Diseases Section, William Beaumont El Paso, Texas Reprints or correspondence: Dr. 80045. Search for other works by this author on: Oxford Academic PubMed Google Scholar Judith Anderson, Anderson John Piper, Piper Naomi Aronson,...
Objective: Study aimed to assess safety, tolerability, and immunogenicity of novel therapeutic HPV-16 E6E7 ISCOMATRIX vaccine for treatment human papilloma virus (HPV)-related anal intraepithelial neoplasia in HIV-infected men who have sex with moderate immunosuppression. Design: Randomized, multicenter, blinded, placebo-controlled, dose-escalating study investigating 3 different doses dose schedule. Primary objective determine safety including clinical status, maintenance virological...
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<b>Objectives:</b> Anal cytology smears are either collected "blind" (swab inserted 4 cm into anal canal and rotated) or guided through an anoscope (transformation zone visualised then sampled). We compared these smear techniques with respect to sample quality patient acceptability. <b>Methods:</b> Using a paired, random sequence clinical trial, 151 homosexual men (n = 95 HIV positive) underwent both at single visit; order was randomised specimens were read blind. Both utilised Dacron swab,...
The Medical Outcomes Study Instrument (MOSI), a 20 item functional health status measure was sent to all women aged 30–40 years (n = 486) in General Practice (list size 6447). There 73% response rate two mailings. Lower scores on six dimensions of the MOSI were associated with number diagnoses and identified mental illness patient summaries, unemployment positive Nottingham Health Profile. In categories, Perceptions Mental Health, lower for those long-term medication. paper suggests that may...
Commercial sex is licensed in Victoria, Australia such that workers are required to have regular tests for sexually transmitted infections (STIs). However, the incidence and prevalence of STIs very low, especially since there almost universal condom use at work. We aimed conduct a cost-effectiveness analysis financial cost testing policy versus health benefits averting transmission HIV, syphilis, chlamydia gonorrhoea clients.We developed simple mathematical model, informed by conservative...