Qinghua Yu

ORCID: 0000-0002-7326-650X
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Research Areas
  • Advanced Nanomaterials in Catalysis
  • Carbon and Quantum Dots Applications
  • Nanocluster Synthesis and Applications
  • Nanoplatforms for cancer theranostics
  • Streptococcal Infections and Treatments
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Diagnosis and Treatment
  • Advanced Radiotherapy Techniques
  • Otolaryngology and Infectious Diseases
  • Infectious Diseases and Tuberculosis
  • Hemoglobinopathies and Related Disorders
  • Diabetic Foot Ulcer Assessment and Management
  • Iron Metabolism and Disorders
  • Erythrocyte Function and Pathophysiology
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Platelet Disorders and Treatments
  • Electrochemical sensors and biosensors
  • Foot and Ankle Surgery
  • Advanced biosensing and bioanalysis techniques
  • Wound Healing and Treatments
  • COVID-19 and healthcare impacts
  • Tuberous Sclerosis Complex Research
  • Pressure Ulcer Prevention and Management
  • Quantum Dots Synthesis And Properties
  • Pancreatitis Pathology and Treatment

Jilin University
2017-2025

First Hospital of Jilin University
2017-2025

Zaozhuang University
2025

Fujian Medical University
2020-2023

Fujian Provincial Hospital
2020-2023

Chongqing Medical University
2021-2022

Chongqing University
2012-2022

Air Force Medical University
2021-2022

Chongqing Cancer Hospital
2022

General Hospital of Guangzhou Military Command
2021

Abstract While apoptotic cell death is known to be central the pathogenesis of radiation-induced liver injury (RILI), mechanistic basis for this activity remains poorly understood. N 6 -methyladenosine (m A) modifications are most common form reversible methylation observed on lncRNAs in eukaryotic cells, with their presence leading pronounced changes a range biological processes. The degree which m A modification plays role induction response ionizing radiation (IR) context RILI...

10.1038/s41419-025-07417-2 article EN cc-by Cell Death and Disease 2025-02-24

Summary Arterial stenosis results in a complex pattern of blood flow containing an extremely fast the throat and post-stenosis low flow. The generates high shear stress that has been demonstrated vitro to activate aggregate platelets. One potential problem these studies is platelets are invariably exposed for period significantly longer than they would have experienced vivo. More importantly, role poststenosis platelet activation aggregation not determined. By exposing profile contains both...

10.1055/s-0037-1613308 article EN Thrombosis and Haemostasis 2002-01-01

Background: Hemorrhage is a major complication of trauma and often becomes more severe in hypothermic patients. Although it has been known that platelets are activated the cold, studies have focused on platelet behavior at 4°C, which far below temperatures encountered In contrast, how function commonly found patients (32–37°C) remains largely unknown, especially when they exposed to significant changes fluid shear stress could occur due hemorrhage, vascular dilation/constriction,...

10.1097/01.ta.0000093366.98819.fe article EN Journal of Trauma and Acute Care Surgery 2004-08-01

To investigate the clinical characteristics and treatment outcomes in necrotizing fasciitis (NF) patients a reconstructive unit northeastern China.Medical records of diagnosed with treated for NF extremities from November 2013 to December 2016 were retrospectively reviewed. Demographic data, presentation, duration signs symptoms, location infection, predisposing factors, causative microbiological organisms, laboratory risk indicator (LRINEC) score, number surgical debridements, length...

10.1186/s12879-017-2907-6 article EN cc-by BMC Infectious Diseases 2017-12-01

Abstract Background Three-dimensional (3D) computed tomography (CT) reconstruction technology has gained attention owing to its potential in locating ground glass nodules the lung. The 3D printing additionally allows visualisation of surrounding anatomical structure and variations. However, clinical utility these techniques is unknown. This study aimed establish a lung tumour an model using chest CT evaluate uniportal video-assisted thoracoscopic segmentectomy. Methods Eighty-nine patients...

10.1186/s12957-020-01998-2 article EN cc-by World Journal of Surgical Oncology 2020-08-24

Summary Platelet functions are increasingly measured under flow conditions to account for blood hydrodynamic effects. Typically, these studies involve exposing platelets high shear stress periods significantly longer than would occur in vivo. In the current study, we demonstrate that platelet response depends on duration of exposure. a 100 dyn/cm2 less 10-20 sec, PRP or washed were aggregated, but minimally activated as demonstrated by P-selectin expression and binding activation-dependent...

10.1160/th03-03-0145 article EN Thrombosis and Haemostasis 2003-01-01

Abstract Background Despite the growing number of studies on coronavirus disease-19 (COVID-19), little is known about association menopausal status with COVID-19 outcomes. Materials and methods In this retrospective study, we included 336 inpatients between February 15, 2020 April 30, at Taikang Tongji Hospital (Wuhan), China. Electronic medical records including patient demographics, laboratory results, chest computed tomography (CT) images were reviewed. Results total, 300 patients...

10.1186/s13293-021-00363-6 article EN cc-by Biology of Sex Differences 2021-01-29

The design and synthesis of a series novel l -arginine-based carbon dot NO-donating drugs for vasodilation tumor suppression.

10.1039/d1bm01184g article EN Biomaterials Science 2021-01-01

Calcaneal fractures are associated with numerous complications and a poor prognosis significant long-term quality-of-life issues, regardless of treatment. Therefore, in-depth research into the underlying mechanism calcaneal fracture is still great interest, goal improving treatment for patients suffering from this condition. This study aimed to investigate relationship between distribution lines their determinants, especially those related internal structure calcaneus. was achieved by maps...

10.1186/s13018-022-02930-y article EN cc-by Journal of Orthopaedic Surgery and Research 2022-01-21

Tumor microenvironment (TME) is intently related to tumor growth, progression and invasion, leading drug resistance insufficient therapeutic efficacy. However, remodeling TME utilizing for exploring intelligent nanomaterials that can realize theranostic still challenging. Nowadays, the based on chemotherapy exposes some deficiencies, such as low targeting, weak permeability premature clearance. Furthermore, it challenging cure drug-resistant tumors effectively. For sake of solving these...

10.1016/j.mtbio.2022.100359 article EN cc-by-nc-nd Materials Today Bio 2022-07-12

The poor penetration of nanomaterials in solid tumours and difficulty monitoring their depth are major obstacles application for the treatment tumours. Herein, pH-responsive carbon dots (ZCD) based on a zeolitic imidazolate framework (ZIF-8) were fabricated to achieve deep delivery chemotherapeutic doxorubicin (DOX) via hierarchical size/charge dual-transformation transcytosis. as-prepared ZCD accumulated tumour acidic microenvironment further triggered its decomposition. Firstly, was...

10.1039/d2nr02134j article EN Nanoscale 2022-01-01

// Liannv Qiu 1 , Yonglie Zhou Qinghua Yu Junde Qian Li 2 and Renhua Sun Department of Clinical Laboratory, Zhejiang Provincial People's Hospital, Hospital Hangzhou Medical College, Hangzhou, 310004, China Intensive Care Unit, Correspondence to: Qiu, email: qlv2012@126.com Keywords: regulatory b cells; acute pancreatitis; interleukin-10; diagnostic utility Received: January 26, 2017 Accepted: November 03, Epub: 2018 Published: 16, ABSTRACT Early stratification the severity pancreatitis (AP)...

10.18632/oncotarget.23911 article EN Oncotarget 2018-01-03

A multimodal anti-tumor nano-agent enhanced the efficiency of photodynamic therapy via photothermal therapy, alleviating hypoxia and Cu 2+ -mediated reactions.

10.1039/d2nj04525g article EN New Journal of Chemistry 2022-01-01

Surgical repair of severe pressure ulcers (PUs) in elderly patients remains a challenge for clinicians due to the complicated comorbidities and special physical characteristics patients. The objective this study was evaluate application couple-kissing flaps (CKF) reconstruction sacral PUs these Elderly (over 70 years) with stage 3 or 4 who underwent CKF immediately after radical debridement between July 2012 December 2015 were enrolled retrospective study. Patients' demographics extracted...

10.1186/s12877-017-0680-4 article EN cc-by BMC Geriatrics 2017-12-01

To date, over 200 families with hereditary leiomyomatosis and renal cell carcinoma (HLRCC) 600 Birt–Hogg–Dubé (BHD) syndrome have been reported, low incidence. Here, we describe a patient suspected rare HLRCC complicated by BHD syndrome. The proband (II1) had characteristic cutaneous leiomyoma-like protrusions on the neck back, left mass multiple right renal, liver bilateral lung cysts. Three family members (I1, II2, II3) history of cancer several aforementioned clinical features. Two (II1,...

10.1136/jmg-2023-109328 article EN Journal of Medical Genetics 2023-07-19

Genetic diagnosis history and osteoarticular phenotype of a non-transfusion secondary hemochromatosis

10.12998/wjcc.v8.i23.5962 article EN World Journal of Clinical Cases 2020-12-03

Abstract Background : Three-dimensional (3D) computed tomography (CT) reconstruction technology has gained increasing attention owing to its potential in locating ground glass nodules the lung. The 3D printing additionally allows visualisation of surrounding anatomical structure and variations. However, clinical utility these techniques is unknown. This study aimed establish a lung tumour an ana tomical model using chest CT evaluate uniportal video-assisted thoracoscopic segmentectomy ....

10.21203/rs.3.rs-19927/v2 preprint EN cc-by Research Square (Research Square) 2020-08-13
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