A5003544304- Radiomics and Machine Learning in Medical Imaging
- Advanced X-ray and CT Imaging
- MRI in cancer diagnosis
- Myasthenia Gravis and Thymoma
- Colorectal Cancer Surgical Treatments
- Radiation Dose and Imaging
- Electrical and Bioimpedance Tomography
- Chromatin Remodeling and Cancer
- Ultrasound in Clinical Applications
- RNA regulation and disease
- Radiology practices and education
- Inhalation and Respiratory Drug Delivery
- Extracellular vesicles in disease
- Photoacoustic and Ultrasonic Imaging
- Advanced Neuroimaging Techniques and Applications
- Colorectal and Anal Carcinomas
- Ultrasound and Hyperthermia Applications
- Carbon and Quantum Dots Applications
- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Advanced MRI Techniques and Applications
- Glioma Diagnosis and Treatment
- Mesenchymal stem cell research
- Advanced Nanomaterials in Catalysis
- Sarcoidosis and Beryllium Toxicity Research
Shanxi Medical University
2014-2024
Hebei University
2024
Zhejiang University
2024
Affiliated Hospital of Hebei University
2024
Second Affiliated Hospital of Zhejiang University
2024
Shanxi Provincial Cancer Hospital
2014-2022
Cancer Hospital of Chinese Academy of Medical Sciences
2022
Abstract Aims To investigate the key factors influencing glioma progression and emergence of treatment resistance by examining intrinsic connection between mutations in DNA damage repair‐related genes development chemoresistance gliomas. Methods We conducted a comprehensive analysis deep‐targeted gene sequencing data from 228 samples. This involved identifying differentially mutated across various grades, assessing their functions, employing I‐TASSER for homology modeling. elucidated...
To investigate the feasibility of using Spectral CT imaging with low contrast medium in abdominal angiography (CTA). 70 consecutive patients (40 men, 42.6 ± 20.4 years; 30 women, 46.7 18.8 years) suspected focal lesions were referred to CTA exam. They randomly assigned into two groups. Group A: 35 underwent conventional scan Tube voltage 120 kVp, automatic current modulation a Noise Index 12, ASIR 30%, and injected Iohexol (350 mgI/ml). B: Imaging, 600 mA, Iodixanol (270 The optimal...
Background Although histological examination is the standard method for assessing genetic status, development of a noninvasive method, which can display heterogeneity whole tumor to supplement genotype analysis, might be important personalized treatment strategies. Purpose To evaluate potential role diffusion kurtosis imaging (DKI)‐derived parameters using histogram analysis derived from whole‐tumor volumes prediction status KRAS mutations in patients with rectal adenocarcinoma. Study Type...
Abstract To evaluate the role of conventional contrast-enhanced CT (CECT) imaging and dual-energy spectral (DECT) perfusion in differentiating WHO histological subtypes thymic epithelial tumours (TETs). Eighty-eight patients with TETs who underwent DECT scans (n = 51) enhancement 37) using a GE Discovery CT750 HD scanner were enrolled this study. The mean maximal range (mean CEmax) parameters lesions analysed. Among six (Type A, AB, B1, B2, B3 thymoma carcinoma), CEmax values most parameter...
Abstract Background To validate a contrast-enhanced CT (CECT)-based radiomics model (RM) for differentiating various risk subgroups of thymic epithelial tumors (TETs). Methods A retrospective study was performed on 164 patients with TETs who underwent CECT scans before treatment. total 130 (approximately 79%, from 2012 to 2018) were designated as the training set, and 34 21%, 2019 2021) testing set. The analysis variance least absolute shrinkage selection operator algorithm methods used...
Abstract Infections caused by Pseudomonas aeruginosa biofilm significantly endanger human health worldwide. Biofilms are closely associated with antibiotic resistance because biofilms undermine the efficacy of antibiotics. A novel ultrasound-launched targeted nanoparticle was developed to universally destroy biofilm, target bacteria, deliver antibiotics, and efficiently kill bacteria via ultrasonic cavitation antibacterial sonodynamic therapy. The consisted poly (lactic-co-glycolic acid)...
Background: Acute kidney injury (AKI) is one of the most important causes mortality and morbidity worldwide. Mesenchymal stem cells (MSCs) can be used for cell-based therapy containing AKI. Magnetic resonance imaging (MRI) an ideal mean tracking by labeling with superparamagnetic iron oxide (SPIO). Therefore, using oxide-labeled mesenchymal (MSC) to treat AKI evaluating migration, distribution, homing MRI method cell in vivo. Methods: In vitro, MSCs were labeled 25 μg/mL 24 h, test...
Objectives: Despite recent advances in the treatment of rheumatoid arthritis (RA), few population-based studies have assessed mortality rates and underlying causes death (UCDs) among patients with RA RA-associated interstitial lung disease (RA-ILD). This study evaluated trends rates, demographic characteristics, UCDs RA-ILD.Method: Using data from certificates (1999-2018) US Centers for Disease Control Prevention Multiple Cause Death files, we explored UCD RA-ILD. Moreover, examined crude...
To evaluate the influence of low-concentration contrast agents and low-tube-voltage computed tomography on chest enhancement examinations, we conducted a multicenter prospective study. A total 216 inpatients enrolled from 12 different hospitals were randomly divided into four groups: A: voltage, 120 kVp; iohexol, 350 mgI/mL; B: 100 kVp, C: iodixanol, 270 D: mgI/mL. Subjective image quality was assessed by two radiologists compared weighted kappa test. The objective scores, scanning radiation...
Objective To investigate the value of magnetic resonance diffusion-weighted imaging (DWI) in combination with peripheral serum tumor markers diagnosis and therapeutic evaluation small cell lung cancer (SCLC) brain metastases. Methods Retrospective analysis 368 SCLC cases diagnosed by histopathology or cytology from February 2009 to 2012 Shanxi Provincial Cancer Hospital was made. All patients underwent pathological examination progastrin-releasing peptide (ProGRP), neuron-specific...
Objective To investigate the application of three stages enhanced scan multi-slice spiral CT for characteristic analysis on wall and lumen colorectal mucous adenocarcinoma.Methods 51 patients with mucinous adenocarcinoma who had complete pathologic diagnosis were studied.GE Discovery 750HD scanner was used line scan,arterial portal venous phase scan,and delayed scan.The lesions intestinal wall,enteric cavity proximal normal observed by related quantitative value observed.Results The uneven...
Objective To evaluate the clinical value of gemstone spectral imaging (GSI) in preliminary assessment esophageal carcinoma pathology features.Methods 58 patients were analyzed which diagnosed with histological as underwent GSI enhanced scans before surgery.The iodine concentrations (IC) lesions measured on iodine-water based material-decomposition images.The results IC evaluated retrospectively different pathological grading,locations and morphology according to final pathologic...
Objective To evaluate the value of 3.0T magnetic resonance multi-b diffusion-weighted imaging (DWI) in evaluating efficacy chemotherapy for patients with central lung squamous cell carcinoma and atelectasis. Methods Twenty were examined by (MRI) (including T1WI, T2WI DWI) before chemotherapy, 2 cycles 4 chemotherapy. The images, tumor volume changes apparent diffusion coefficient (ADC) analyzed. Results In cancer atelectasis, atelectasis could be distinguished on MRI examination...
Objective: To evaluate the predictive value of MRI features and pathological parameters on local recurrence, metastasis progression free survival (PFS) for locally advanced rectal cancer after neoadjuvant chemoradiotherapy subsequent total mesorectal excision surgery. Methods: A retrospective analysis 95 patients with adenocarcinoma who underwent was performed. Univariate multivariate analyses were performed to before chemoradiation postoperative survival. Results: Among cases, 5 cases...