- Vestibular and auditory disorders
- Ophthalmology and Eye Disorders
- Tracheal and airway disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Cerebral Venous Sinus Thrombosis
- Head and Neck Cancer Studies
- Voice and Speech Disorders
- Glaucoma and retinal disorders
- Ear Surgery and Otitis Media
- Salivary Gland Tumors Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Ear and Head Tumors
- Dysphagia Assessment and Management
- Vascular Anomalies and Treatments
- Tumors and Oncological Cases
- Head and Neck Surgical Oncology
- Circular RNAs in diseases
- Myofascial pain diagnosis and treatment
- COVID-19 and healthcare impacts
- Genetic Neurodegenerative Diseases
- Spinal Cord Injury Research
- Gastric Cancer Management and Outcomes
- Botulinum Toxin and Related Neurological Disorders
- Oral health in cancer treatment
- Mechanical Circulatory Support Devices
Ospedale Antonio Cardarelli
2019-2021
University of Campania "Luigi Vanvitelli"
2008-2019
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli
2018
Azienda Ospedaliera G.Rummo
2013-2017
Fatebenefratelli Hospital
2017
University of Naples Federico II
2013-2016
Textron Systems (United Kingdom)
2015
Fresenius Medical Care (Germany)
2013
Fondazione Santa Lucia
2011
Laryngeal cancer (LCa), a neoplasm of the head and neck region, is leading cause death worldwide. Surgical intervention remains mainstay LCa treatment, but crucial point represented by possible nodal involvement. Therefore, it urgently needed to develop biomarkers therapeutic tools able drive treatment approaches for LCa. In this study, we investigated deregulated microRNAs (miRNAs) in tissues from patients with either lymph node metastases (N+) or not (N−). miRNA expression profiling was...
Airway stenting is the chosen treatment for patients affected by subglottic tracheal stenosis and unfit surgery. Among different types of prostheses, Dumon stent a valid option especially in without tracheotomy. Insertion usually achieved pushing off from loader using prosthesis pusher. If expelled below stenosis, rigid forceps grasping proximal end retract it above stenosis. However, difficult cases such as with luminal diameter smaller than profile stent, manoeuvre may be non-expert hands....
Study the high-frequency vestibulo-oculomotor reflex in posterior canal benign paroxysmal positional vertigo (BPPV) through Video Head Impulse Test (vHIT).150 patients suffering for first time from BPPV were studied. Posterior vestibulo ocular (VOR) gain was analysed stimulations right anterior-left and left anterior-right planes before treatment, immediately after resolution of acute stage one month later. Results compared with a group 100 healthy individuals.No significant difference...
Temporal bone fractures are a common lesion of the base skull. The diagnosis and management temporal require multidisciplinary approach. Variable clinical presentations may arise from such fractures, ranging an asymptomatic course to very serious consequences. aim this study was report our experience with series patients propose diagnostic/therapeutic algorithm. This enrolled 141 patients, 96 (68.1%) males 45 (31.9%) females, in age 20 60 (average age: 39 ± 4.1 years), who were referred...
Functional taping with elastic bandages and adhesive tapes could limit the action of upper limb spastic muscles sustain that weaker in children hemiplegic cerebral palsy (CP). 16 young CP (3±2 years old) were enrolled this pilot study including 5 months conjunction conventional physical therapy, followed by 7 therapy alone (taping wash-out), other plus therapy. Large improvements Melbourne assessment score found first period which was used (+15.4%, p<0.001) also second one despite 8...
The most common form of posterior canal benign paroxysmal positional vertigo (BPPV) is characterised by positional, paroxysmal, upbeat nystagmus, with a torsional component beating towards the downward ear. Rarer variants have been reported, putatively due to either position otoconia in or anatomic variations semicircular canals. frequent less apogeotropic BPPV, which nystagmus downbeat and apogeotropic. In this form, main problems are differential diagnosis central mimics BPPV...
Non-melanoma skin cancers (NMSCs) include a heterogeneous group of malignancies arising from the epidermis, comprising squamous cell carcinoma (SCC), basal (BCC), Merkel and more rare entities, including malignant pilomatrixoma sebaceous gland tumours. The treatment early disease depends primarily on surgery. In addition, certain patients present with extensive local invasion or metastasis, which renders these tumours surgically unresectable. Improving outcome radiotherapy through use...
We report a case of granulations that complicated subglottic stent placement and completely destroyed vocal folds with luminal obstruction. A microbial aetiology significantly contributed to the occurrence associated mechanical irritation. The were successfully resected using digital AcuBlade laser system, new generation CO2 used in otorhinolaryngology, particularly cord disease. It permitted precise control scan line between fold granulation for several reasons. was electronic integrated...
Adenoid cystic carcinoma (ACC) is a relatively rare tumor that accounts for <1% of all head and neck malignancies. Laryngeal localization ACC, which most commonly hypoglottic, rare, occurring in 0.07-0.25% laryngeal tumors. ACC characterized as slow-growing with high recurrence rate, often causes dyspnea hoarseness. exhibits propensity perineural invasion thus, patients may experience pain late symptom the disease. Distant metastasis occurs 35-50% cases lungs are common site metastasis....
To determine the utility of hyperventilation test (HVT) in diagnosis vestibular schwannoma (VS).A retrospective analysis hyperventilation-induced nystagmus (HVIN) 45 patients with unilateral VS.A tertiary referral center.Forty-five VS; 30 chronic neuritis; 20 healthy subjects normal hearing and without symptoms or a history vertigo, migraine, neurological diseases (control group).Audiological examination; "side-stream" measurement end-tidal CO2 pressure (P(EtCO2)) to standardize procedure;...
Background: Myotonic dystrophy type 1 (DM1) is an autosomal-dominant inherited disorder clinically characterized by variable systemic manifestations. Among clinical features of the disease, 'precocious presbyacusis' has been previously reported. The underlying mechanism this auditory impairment remains still poorly understood. Hearing active process located in cochlea, where outer hair cells (OHCs) play important role sound perception through a 'contractile' like movement resembling skeletal...
<b><i>Objectives:</i></b> This study evaluates maintenance cetuximab administered every 2 weeks (q2w) after chemotherapy plus as first-line treatment in a series of patients with head and neck squamous cell cancer compares the results those obtained historical control group receiving weekly cetuximab. <b><i>Methods:</i></b> After treatment, Group A, 36 enrolled from October 2016 to November 2017, received biweekly cetuximab, at 500...
The aim of this study was to assess the long-term effectiveness quantic molecular resonance (QMR) in treatment inferior turbinate hypertrophy (ITH) allergic and nonallergic rhinitis refractory medical therapy.This enrolled 281 patients, 160 males (56.9%) 121 females (43.1%), mean age 37.8 ± 4.1 years, range 18 71. Fifty-four patients have been lost follow up therefore excluded from final analysis. Based on skin prick test results, 69 were considered (group A) 158 B). All subjects underwent...
Gli obiettivi dello studio sono stati: identificare segni di sofferenza vestibolare attraverso un protocollo bed-side examination in caso ipoacusia improvvisa monolaterale senza clinici vestibolare; proporre i risultati della bed side examination come criterio per lesecuzione mirata RMN canali acustici interni sospetto neurinoma dell VIII nervo cranico. Sono stati valutati 96 pazienti, 52 uomini e 44 donne, con neurosensoriale che non presentavano né vertigine nistagmo spontaneo....