A5054676608- Hormonal and reproductive studies
- Health disparities and outcomes
- Pharmacology and Obesity Treatment
- Diet and metabolism studies
- Ovarian function and disorders
- Bone health and osteoporosis research
- Nutrition and Health in Aging
- Liver Disease Diagnosis and Treatment
- Body Composition Measurement Techniques
- Diabetes Treatment and Management
- Regulation of Appetite and Obesity
- Metabolism, Diabetes, and Cancer
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Muscle metabolism and nutrition
- Elder Abuse and Neglect
- Psoriasis: Treatment and Pathogenesis
- Infectious Diseases and Tuberculosis
- Hidradenitis Suppurativa and Treatments
- Lipid metabolism and disorders
- Chronic Disease Management Strategies
- Connexins and lens biology
- Chemical Synthesis and Characterization
- Air Quality and Health Impacts
- Biochemical effects in animals
- Diverticular Disease and Complications
National Defense Medical Center
2017-2025
Taichung Armed Forces General Hospital
2006-2025
VA Puget Sound Health Care System
2024
Chung Shan Medical University
2014-2022
Central Taiwan University of Science and Technology
2014
Sodium-glucose cotransporter-2 inhibitors (SGLT2i), a novel class of antidiabetic medications, have emerged as key treatment option for diabetes management. Notably, SGLT2i promote glucose and sodium excretion through urine, mechanism that may be implicated in the potential association between use atopic dermatitis (AD) risk. This study investigated relationship new-onset AD diabetic patients. nationwide active-comparator cohort utilized data from Taiwan National Health Insurance Database to...
Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive fat accumulation in the liver. Intracellular oxidative stress induced lipid leads to various hepatocellular injuries including fibrosis. However, no effective method for mitigating MASLD without substantial side effects currently exists. Molecular hydrogen (H
Background: Little epidemiological research has investigated the associations of air pollutant exposure over various time windows with older adults' symptoms depression. This study aimed to analyze relationships long- and short-term ambient pollution (to coarse particulate matter, O 3 , SO 2 CO, NO x ) depressive in a sample community-dwelling adults. Methods: A adults ( n = 1,956) was recruited from nationally representative multiple-wave (Taiwan Longitudinal Study on Aging). Between 1996...
Gout is a common systemic inflammatory disease with male predominance. This study aimed to determine the relationship between serum total testosterone level and hyperuricemia. Data on 1899 men, collected from 2007 2017, were included in analysis. Serum urate (SU) measured enrolment. The primary endpoints SU levels ≥ 7 mg/dL ≥9 mg/dL. On enrolment, participants had mean age of 45.6 years 510 ng/dL 6.6 mg/dL, respectively. 533 470 patients < ≥7 respectively (p 0.001); 515 425 9 0.001). After...
To evaluate whether the effects of providing or receiving social support are more beneficial to reduce mortality risk among elderly with different educational levels.
To assess the relationship between changes in abdominal adipose tissue and metabolic syndrome (MetS) men with obesity after a weight reduction program (WRP).Adult MetS were recruited for this prospective single-arm intervention study. Participants consumed an energy-restricted diet of 1200 kcal/day performed 50-mins aerobic exercise daily 12 weeks. Changes components recorded. subcutaneous fat area (SAFA) intra-abdominal (IAFA) at umbilicus level determined using magnetic resonance imaging.A...
To assess the association between serum testosterone (T) and metabolic syndrome (MS) in different age groups Taiwanese men.Male participants, regardless of or any underlying disease, were identified from MJ Health Screening Center Taiwan 2007 to 2016 for this cross-sectional study. They divided into three according age, further classified MS diagnosis. Basic patient characteristics with relevant parameters obtained. One-way ANOVA mean T values numbers measures that exceeds cut-off components...
Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas frequently underestimated. We conducted dual-energy x-ray absorptiometry (DXA) 7-site skinfold (SF) and dominant hand grip strength measurements among patients type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 T2DM (60 females 43 males), aged between 50 80 years (median 68.0 years) were enrolled 45 non-DM also included compare females. Our results revealed was...
This longitudinal study evaluated the direct effects of providing/receiving family support on mortality in older adults with different living arrangements Taiwan. All data analysed were obtained from Taiwan Longitudinal Study Aging, 1996-2007, residents aged ⩾67 years (1,492 men and 1,177 women) Taiwan's National Death Register. Living divided into alone, only spouse, others. Support was mainly defined as two categories: providing receiving. The effect using Cox regression by arrangement....
Low testosterone levels are associated with increased risk of cardiovascular disease; however, most previous studies assessed the relationship a history (CV) events rather than CV prediction scores consequently neglecting effect on in healthy young individuals. The aim this study was to investigate between and predict 10-year disease. This retrospective cohort conducted through large medical health examination system four metropolises Taiwan. Two were used participants: Framingham Risk Score...
Here, we present a case of ACTH-dependent pituitary macroadenoma (Cushing's disease) resulting in secondary amenorrhea mimicking polycystic ovary syndrome (PCOS). A 20-year-old nulligravid woman had been suffering from oligomenorrhea, amenorrhea, and moderate hirsutism since the age 18 years. She visited gynecologic clinic where PCOS was impressed according to clinical manifestation ultrasound finding. The patient responded medication 1st year, but gradually failed induce menses. advised...
Despite previous concerns about ocular side effects related to amiodarone, the relationship between amiodarone and cataract remains uncertain. Therefore, this study aimed assess potential association use subsequent risk of cataract, taking into account confounders.
We evaluated hyperglycemia-associated mortality in the Taiwanese population by conducting a 10-year retrospective cohort study.From 2007 to 2017, all participants, regardless of their age or underlying diseases, were identified at Health Screening Center Taiwan. Overall, 114,534 participants included analysis. They classified into three subgroups according glycemia and smoking status combining survival for data analysis.The mean follow-up time, age, body mass index (BMI) 8.14 ± 2.22 years,...
Abstract Increased insulin resistance (IR); decreased glucose effectiveness (GE); and both first-and second phase of secretion (FPIS, SPIS) have always been important factors for the development type 2 diabetes. Therefore, in this study, we evaluated relationships between thyroid-stimulating hormone (TSH) these 4 adult Chinese. We randomly enrolled 24,407 men 24,889 women 30 59 years old. IR, FPIS, SPIS GE were measured with equations built by our group. The t test was performed to evaluate...
Background Aging-related hypogonadism in men is related to the deterioration of overall health. Those with this disease rarely receive treatment. The hypertriglyceridemic waist (HTGW) phenotype a tool for predicting abnormalities cardiovascular metabolism. However, relationship between HTGW and remains undetermined. This study aimed determine association different age groups. Methods Data cross-sectional were obtained from MJ Health Screening Center Taiwan 2007 2016. was divided into four...
To evaluate the blood glucose and renal function, determine prevalence of hyperglycemia/diabetes mellitus (DM) disease (nephropathy), investigate association between hyperglycemia/DM in patients with viral hepatitis (VH).A total 491 subjects were included study. Patients VH further divided into B virus (HBV) infection, C (HCV) HBV-HCV co-infection subgroups. Fasting glucose, glycated hemoglobin (HbA1c), albumin (GA), glutamic oxaloacetic transaminase (GOT), creatinine (Cr), cystatin (Cys C)...
Introduction. To evaluate whether waist circumference (WC) or hyperglycemia is more closely associated with hypogonadism in middle-aged men. Research Design and Methods. This cross-sectional study analyzed male participants under 65 years old from the MJ Health Screening Center Taiwan 2007 to 2016. Basic patient characteristics relevant parameters were obtained. We used chi-square test perform a correlation analysis for HbA1c WC between without hypogonadism. A one-way ANOVA post hoc...
Abstract Background Diabetes with co-existing bone fragility or osteoporosis is common in elderly patients, whereas frequently underestimated. Methods We conducted dual-energy x-ray absorptiometry (DXA) 7-site skinfold (SF) and dominant hand grip strength measurements among patients type 2 diabetes (T2DM) to assess their gender-specific associations. A total of 103 T2DM (60 females 43 males), aged between 50–80 years (median 68.0 years) were enrolled. Results Our results revealed was...
Background: Hemodialysis (HD) is a public health issue, and HD-induced infection major risk factor for mortality. Toll-like receptor 4 (TLR4) plays key role in the pathogenesis of infection. However, polymorphisms TLR4 contribute to are still unknown. Aim: This study aimed examine correlation between mortality among HD patients. Methods: retrospective cohort included 585 participants from Tri-Service General Hospital Taipei 2011 2015. All were genotyped rs10116253T/C rs7873784G/C by iPLEX...
Aims: Leptin has been shown to predict risk of metabolic syndrome (MetS), but it is not known whether this association independent body composition. Thus, we examined plasma leptin concentration predicted MetS after adjustment for composition measured using imaging. Methods: We used the modified ATP III criteria an Asian population classify participants in longitudinal Japanese-American Community Diabetes Study as presence MetS. Participants without at baseline (n=283) were followed its...