Ning Zhu

ORCID: 0000-0002-7535-1310
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About
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Research Areas
  • Sulfur-Based Synthesis Techniques
  • Chemical Synthesis and Reactions
  • Crystallization and Solubility Studies
  • Carbon dioxide utilization in catalysis
  • X-ray Diffraction in Crystallography
  • Ferrocene Chemistry and Applications
  • Organometallic Complex Synthesis and Catalysis
  • Cytokine Signaling Pathways and Interactions
  • Lung Cancer Treatments and Mutations
  • Molecular Junctions and Nanostructures
  • Metal-Organic Frameworks: Synthesis and Applications
  • Metal complexes synthesis and properties
  • Synthesis and biological activity
  • Asymmetric Hydrogenation and Catalysis
  • Cancer Mechanisms and Therapy
  • RNA modifications and cancer
  • Drug Solubulity and Delivery Systems
  • Synthesis and Characterization of Heterocyclic Compounds
  • CO2 Reduction Techniques and Catalysts
  • Photonic and Optical Devices
  • Analytical Chemistry and Chromatography
  • Lanthanide and Transition Metal Complexes
  • Multicomponent Synthesis of Heterocycles
  • Molecular Sensors and Ion Detection
  • Power Systems and Renewable Energy

Inner Mongolia University of Technology
2016-2025

Wuhan University
2022-2025

Beijing Agricultural Machinery Research Institute
2025

Mongolian University of Science and Technology
2010-2024

Zhejiang University
2005-2024

Inner Mongolia Electric Power Survey & Design Institute (China)
2024

Shandong University
2023-2024

Lanzhou University of Technology
2022-2024

Yuhuangding Hospital
2024

Second Affiliated Hospital of Zhejiang University
2024

Type 3 adenylyl cyclase (Adcy3) is localized to the cilia of olfactory sensory neurons (OSNs) and an essential component cyclic adenosine monophosphate (cAMP) signaling pathway. Although role this enzyme in odor detection axonal projection OSNs was previously characterized, researchers will still have determine its function maturation postnatal cilium ultrastructure. Previous studies on newborns showed that anatomic structure main epithelium (MOE) Adcy3 knockout mice (Adcy3-/-)...

10.3389/fncel.2017.00001 article EN cc-by Frontiers in Cellular Neuroscience 2017-01-18

Human tumors harbor a plethora of microbiota. It has been shown that the composition and diversity intratumor microbiome are significantly associated with survival patients pancreatic ductal adenocarcinoma (PDAC). However, association in Chinese as well effect different microorganisms on inhibiting tumor growth unclear. In this study, we collected samples resected from long-term short-term PDAC survivors performed 16S rRNA amplicon sequencing. We found time were different, differential...

10.3389/fimmu.2022.785422 article EN cc-by Frontiers in Immunology 2022-01-25

Despite the encouraging efficacy of anti-PD-1/PD-L1 immunotherapy in microsatellite-instability-high/deficient mismatch repair (MSI-H/dMMR) advanced gastrointestinal cancer, many patients exhibit primary or acquired resistance. Using multi-omics approaches, we interrogate gut microbiome, blood metabolome, and cytokines/chemokines with MSI-H/dMMR cancer (N = 77) at baseline during treatment. We identify a number microbes (e.g., Porphyromonadaceae) metabolites arginine) highly associated...

10.1016/j.xcrm.2023.101355 article EN cc-by-nc-nd Cell Reports Medicine 2024-01-01

Kv4.3 channels are important molecular components of transient K<sup>+</sup> currents (Ito currents) in brain and heart. They involved setting the frequency neuronal firing heart pacing. Altered channel expression has been demonstrated under pathological conditions like failure indicating their critical role function. Thyroid hormone studies suggest that may be hormonally regulated. To explore possibility sex hormones control expression, we investigated whether its changes pregnant uterus....

10.1074/jbc.m101058200 article EN cc-by Journal of Biological Chemistry 2001-08-01

Previous studies have profiled the gut microbiota among psoriatic patients compared to that healthy individuals. However, a comprehensive understanding of magnitude, direction, and detailed compositional functional profiles remains limited. Additionally, research exploring in context both plaque psoriasis (PsO) arthritis (PsA) is lacking. To assess taxonomic characteristics PsO PsA investigate potential links between disease pathogenesis. We collected fecal samples from 70 (44 26 PsA) 25...

10.1128/spectrum.01154-23 article EN cc-by Microbiology Spectrum 2024-03-05

We describe a 14-bit 2.5GS/s non-interleaved pipelined ADC that relies on correlation-based background calibrations to correct the inter-stage gain, settling (dynamic), kick-back and memory errors. A new technique is employed inject large dither signal input non-linear driver, another injected any residual non-linearity in pipeline. In order effect of aging comparators, calibration comparator offsets. The fabricated as dual 28nm CMOS process. An optional interleaved mode provided, where two...

10.1109/vlsic.2016.7573537 article EN 2016-06-01

The Three-River Headwater Region (TRHR) of China is a typical representative the alpine environment in Central Asian plateau and grassland world. Grassland degradation one its serious ecological problems. purpose this study to quantify joint impacts climate human activities on changes TRHR after two phases Ecological Conservation Construction Project (Ecological Project). vegetation coverage selected as an indicator for analyzing changes. We adopt Sen+Mann-Kendall trend analysis, residual...

10.1016/j.geosus.2022.05.003 article EN cc-by-nc-nd Geography and sustainability 2022-06-01

Abstract In this work, two ionic liquids (ILs) immobilized metal‐organic frameworks (MOFs), Fe‐MIL‐101‐3N(BuBr) and Fe‐MIL‐101‐N(Bnme 2 )Br, were obtained by modifying amino groups in Fe‐MIL‐101‐NH with bromobutane quaternary ammonium salt. The liquid MOFs have Lewis acid sites (Fe 3+ ) nucleophilic (Br − ), which can synergistically catalyze the cycloaddition reaction of CO epoxides. Various cyclic carbonate derivatives excellent yields under optimal conditions. Additionally, we found that...

10.1002/slct.202304544 article EN ChemistrySelect 2024-01-26

As an international metropolis, Beijing still plays a key role in the development of national agricultural production technology despite its small regional scale. Climate change has great impact on production. Previous studies often focus single short-term meteorological factor and lack more systematic analysis climate resources Beijing. Based daily temperature, precipitation, relative humidity, wind speed sunshine hours 17 stations past 42 years, this study analyzed spatial temporal...

10.3390/agriculture15040371 article EN cc-by Agriculture 2025-02-10

In recent years, cyclic peptides have emerged as a research hotspot in drug development due to their excellent stability, high specificity, and potential penetrate intracellular targets. However, existing computational models still face challenges making accurate predictions of the structures containing unnatural amino acids (unAAs), thereby limiting application design. The release AlphaFold 3 (AF3) has significantly improved modeling capability biomolecular complexes supports definition...

10.1101/2025.03.06.641792 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2025-03-11

10.1016/j.jde.2025.113224 article EN Journal of Differential Equations 2025-03-12

We identified a novel MaxiK α subunit splice variant (SV1) from rat myometrium that is also present in brain. SV1 has 33-amino acid insert the S1 transmembrane domain does not alter overall hydrophobicity, but makes S0–S1 linker longer. was transfected HEK293T cells and studied using immunocytochemistry electrophysiology. In non-permeabilized cells, N-terminal c-Myc- or C-terminal green fluorescent protein-tagged displayed no surface labeling currents. The lack of functional expression due...

10.1074/jbc.m008852200 article EN cc-by Journal of Biological Chemistry 2001-05-01

A novel, green, and economic CaCO3 synthesis method using a CO2-storage material (CO2SM) was developed based on the strategy of carbon capture, utilization, storage (CCUS). In this process, CO2SM used as both CO2 source crystal modifier to regulate control crystallization CaCO3. 1,4-Butanediol (BDO) and/or 1,2-ethanediamine (EDA) from played unexpected roles surfactant, structure-directing agent, pH modulator. The effects concentrations, reaction temperatures, times were systematically...

10.1021/acssuschemeng.5b01793 article EN ACS Sustainable Chemistry & Engineering 2016-05-13

A new CO2 fixation process into solid -storage materials (CO2 SMs) under mild conditions has been developed. The novel application of amine-glycol systems to the capture, storage, and utilization with readily available 1,2-ethanediamine (EDA) ethylene glycol derivatives (EGs) was demonstrated. Typically, SMs were isolated in 28.9-47.5 % yields, followed by extensive characterization using (13) C NMR, XRD, FTIR. We found that especially resulting poly-ethylene-glycol-300-based SM (PCO2 SM)...

10.1002/cphc.201500206 article EN ChemPhysChem 2015-05-07
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