A5022063932- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- Fluoride Effects and Removal
- Bone and Dental Protein Studies
- Dental Erosion and Treatment
- Salivary Gland Disorders and Functions
- Folate and B Vitamins Research
- Dental Implant Techniques and Outcomes
- Dental materials and restorations
- Antimicrobial Peptides and Activities
- Anesthesia and Neurotoxicity Research
- Diet and metabolism studies
- Dental Trauma and Treatments
- Nutritional Studies and Diet
- Muscle metabolism and nutrition
- Protease and Inhibitor Mechanisms
- Cancer, Hypoxia, and Metabolism
- Protein Hydrolysis and Bioactive Peptides
- Dental Radiography and Imaging
- Diabetes Treatment and Management
- Apelin-related biomedical research
- Dental Anxiety and Anesthesia Techniques
- Pickering emulsions and particle stabilization
- Laser Applications in Dentistry and Medicine
- Medical and Biological Ozone Research
Universidade de São Paulo
2015-2024
Universidade Estadual Paulista (Unesp)
2024
Universidade São Francisco
2015
Introduction: A biomarker is a biological indicator of normal or pathogenic processes. Identification biomarkers useful for the prevention, diagnosis and prognosis diseases as well monitoring progression pathological disorders. Several types molecules present in fluids can act such DNA, coding non-coding RNA, lipids, metabolites, proteins even microbes. In this context, saliva emerges diagnostic tool detection involved with oral systemic diseases, since it reflects pathophysiological...
<b><i>Introduction:</i></b> This study investigated the changes in acquired enamel pellicle (AEP) proteome when this integument is formed vivo after treatment with sugarcane-derived cystatin (CaneCPI-5), hemoglobin (HB), and a statherin-derived peptide (StN15), or their combination then exposed to an intrinsic acid challenge. The effectiveness of these treatments preventing erosion was also evaluated. <b><i>Methods:</i></b> Ten volunteers,...
<b><i>Introduction:</i></b> The identification of acid-resistant proteins, including hemoglobin (Hb), within the acquired enamel pellicle (AEP) led to proposition “acquired engineering” concept, which involves modification AEP by incorporating specific presenting a novel strategy prevent dental demineralization. <b><i>Objective:</i></b> Combining in vivo and vitro proof-of-concept protocols, we sought reveal impact engineering with Hb protein...
The role of fluoride (F) in oxidative stress is well reported, but its effects on the lipid metabolism has not been completely explored Background Here, we evaluated relationship diet and F-induced to liver rats eating normocaloric or hypercaloric diets for two time periods (20 60 days). Methods Seventy-two 21-day-old Wistar were divided into 2 groups (n = 36) based type they eating; each these was then further another 18) either 20 days, a total four groups. Each 3 subgroups 6...
The antimicrobial and anticaries effects of CaneCPI-5 were evaluated. Ninety bovine enamel samples treated for 60 s with either phosphate-buffered-saline (PBS), 0.12% chlorhexidine (CHX), 0.05 mg ml−1 CaneCPI-5, 0.1 or 0.5 CaneCPI-5. They incubated inoculum (human saliva + McBain's saliva) the first 8 h. From then until end experiment, was exposed to McBain sucrose and, once a day, 5 days, they solutions. At experimental period, resazurin viable plate count assays performed. Enamel...
The objective of this study was to compare the protein profile acquired enamel pellicle (AEP) formed in vivo patients with or without gastroesophageal reflux disease (GERD), and erosive tooth wear (ETW). Twenty-four volunteers were divided into 3 groups: 1) GERD ETW; 2) 3) control (without GERD). AEP 120 min after prophylaxis collected from lingual/palatal surfaces. samples subjected mass spectrometry (nLC-ESI-MS/MS) label-free quantification by Protein Lynx Global Service software. A total...
ObjectiveTo assess the efficacy of metal artifact reduction algorithm (MARA) Cranex 3D cone beam computed tomography (CBCT) device in detection peri-implant dehiscence and fenestration around zirconia implants.Study designIn total, 60 implants were placed bovine ribs. Dehiscence defects created implants, after which CBCT images obtained with without activation MARA. Three radiologists examined for presence defects. The area under curve (AUC) from receiver operating characteristic analysis,...
Changes in the proteomic profile of acquired enamel pellicle (AEP) formed for 3 min or 2 h after rinsing with a peptide containing 15 N-terminal residues statherin, serines and phosphorylated (StatpSpS), were evaluated. Nine volunteers participated consecutive days. Each day, professional tooth cleaning, they rinsed 1 10 mL phosphate buffer 1.88 × 10<sup>−5</sup> M StatpSpS only (control). The on was collected electrode filter papers soaked 3% citric acid. After protein...
The aim of this study was evaluated the influence radiation as well new formulations artificial saliva on development root dentin lesions. Bovine samples were divided into: irradiated (70 Gy) or not; type biofilm (from patient-experimental non-irradiated patient-control) and (for condition dentin/biofilm from patient): Control Artificial Saliva (inorganic); + 1 mg/ml hemoglobin; +0.1 cystatin; hemoglobin Bioextra (positive control) deionized water (DiW, negative (n = 12/group). Biofilm...
AbstractAbstractThis study evaluated the antimicrobial and anticaries effects of toothpaste containing hydroxyapatite nanoparticles (nanoHAP − 5 or 10%), xylitol (2 3%) propolis (1 2%), associated not with 1500 ppm fluoride (F). An in vitro model was used microcosm biofilm produced from a pool human saliva McBain (1:50) first 8 h culture on 162 bovine enamel specimens. At end experimental period, analyses metabolic activity, colony forming units (CFU) transverse microradiography (TMR) were...
Fluoride (F) can induce changes in the expression of several liver proteins, most them localized mitochondria and its effect is dose- time-dependent. This study analyzed distinct F concentrations exposure periods on mitochondrial activity complex I-III II-III liver. Thirty-six 21-day-old male Wistar rats were divided into 2 groups (n = 18) according to duration treatment (20 or 60 days). They subdivided 3 subgroups 6) concentration (0 mg/L, 15 mg/L 50 mg/L). After experimental periods,...