A5015437293- Rheumatoid Arthritis Research and Therapies
- Neuroinflammation and Neurodegeneration Mechanisms
- Pregnancy and preeclampsia studies
- Neurogenesis and neuroplasticity mechanisms
- Chronic Lymphocytic Leukemia Research
- Cystic Fibrosis Research Advances
- Biosimilars and Bioanalytical Methods
- Neonatal Respiratory Health Research
- Immune cells in cancer
- Chemokine receptors and signaling
- Electrolyte and hormonal disorders
- Immunodeficiency and Autoimmune Disorders
- Single-cell and spatial transcriptomics
- Clinical practice guidelines implementation
- Pluripotent Stem Cells Research
- Pancreatic function and diabetes
- Ovarian function and disorders
- Diabetes Management and Education
- Circadian rhythm and melatonin
- Systemic Lupus Erythematosus Research
- Gene Regulatory Network Analysis
- Biomedical Research and Pathophysiology
- HIV/AIDS drug development and treatment
- Cell Image Analysis Techniques
- Autoimmune and Inflammatory Disorders Research
AbbVie (Germany)
2018-2019
University of Duisburg-Essen
2016-2018
Essen University Hospital
2015-2018
Klinik für Frauenheilkunde
2018
RWTH Aachen University
2014-2015
Janssen (Belgium)
2013
North Manchester General Hospital
2013
Hasselt University
2006
Reproducibility in molecular and cellular studies is fundamental to scientific discovery. To establish the reproducibility of a well-defined long-term neuronal differentiation protocol, we repeated comparison same two iPSC lines across five distinct laboratories. Despite uncovering acceptable variability within individual laboratories, detect poor cross-site differential gene expression signature between these lines. Factor analysis identifies laboratory as largest source variation along...
A broad spectrum of diseases is characterized by myelin abnormalities and/or oligodendrocyte pathology. In most, if not all, these diseases, early activation microglia occurs. Our knowledge regarding the factors triggering is, however, incomplete. this study, we used cuprizone model to investigate temporal and causal relationship apoptosis activation. Genome-wide gene expression studies revealed induction distinct chemokines, among them Cxcl10, Ccl2, Ccl3 in cuprizone-mediated apoptosis....
<h3>Background</h3> Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disorder that, if inadequately treated, often progresses to joint destruction. Currently, patients are initially treated with conventional disease- modifying anti-rheumatic drugs (DMARDs); in an inadequate response (IR), biologic DMARDs combined methotrexate (MTX) or other improve efficacy. <h3>Objectives</h3> To compare the relative efficacy and safety of abatacept versus all relevant MTX-IR RA....
Purpose: We investigated the potential value of maternal serum copeptin, midregional proatrial natriuretic peptide (MR-proANP) and Procalcitonin (PCT) levels at 11 – 13 weeks' gestation in prediction preeclampsia (PE) a case-control study.
Im Rahmen einer Fall-Kontroll-Studie untersuchten wir die Biomarker PCT, MRproANP und Copeptin im mütterlichen Serum in der 11 – 13. SSW für Prädiktion Präeklampsie (PE).
Im Rahmen einer Fall-Kontroll-Studie untersuchten wir die Biomarker PCT, MRproANP und Copeptin im mütterlichen Serum in der 11 – 13. SSW für Prädiktion Präeklampsie (PE).