A5005598217- Heart Failure Treatment and Management
- Chronic Disease Management Strategies
- Cystic Fibrosis Research Advances
- Cardiac pacing and defibrillation studies
- Medication Adherence and Compliance
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Health and Mental Health
- Potassium and Related Disorders
- Medical Practices and Rehabilitation
- Health and Medical Studies
- Inhalation and Respiratory Drug Delivery
- Pharmaceutical studies and practices
- Family Caregiving in Mental Illness
- Multiple Myeloma Research and Treatments
- Blood Pressure and Hypertension Studies
- Pneumonia and Respiratory Infections
- Cardiac, Anesthesia and Surgical Outcomes
- Nursing care and research
- Diabetes Management and Research
- Healthcare Systems and Public Health
- Economic and Environmental Valuation
- Cardiovascular Function and Risk Factors
- Liver Disease and Transplantation
- Click Chemistry and Applications
- Adolescent and Pediatric Healthcare
Novartis (Switzerland)
2013-2022
Novartis (Sweden)
2018
Novartis (United States)
2014
Chronic heart failure (HF) is associated with significant healthcare expenditure, morbidity, and mortality. This study investigated the epidemiology of HF in Germany. retrospective used anonymous claims data from German Health Risk Institute on individuals statutory health insurance. Patients uninterrupted 1 January 2009 to 31 December 2013 or death (whichever occurred first), ≥2 recorded HF-related diagnoses 2011, were included. newly diagnosed identified. followed up for 2 years first...
Purpose: Family and friends play a pivotal role in caring for patients with heart failure (HF); however, evidence of the impact caregiving is limited. The objectives this study were to describe burden on informal caregivers chronic HF China. Materials methods: A cross-sectional survey cardiologists, their HF, those patients’ was conducted. Patient record forms completed by 150 cardiologists 10 consecutive patients. Caregivers these invited complete questionnaire. Results: Overall, 458...
Adherence to treatment guidelines affects outcomes in patients with chronic heart failure (HF). We investigated patient pathways and patterns for HF Germany.This retrospective study used anonymous healthcare claims data from the German Health Risk Institute on individuals statutory health insurance. Patients uninterrupted 1 January 2009 31 December 2013 or death (whichever occurred first), ≥2 recorded HF-related diagnoses 2011, were included. newly diagnosed identified. Use of recommended by...
Purpose: Little evidence exists on the burden that chronic heart failure (HF) poses specifically to patients in China. The objective of this study, therefore, was describe HF Materials and methods: A cross-sectional survey cardiologists their with conducted. Patient record forms were completed by 150 for 10 consecutive patients. Patients whom a patient form invited complete questionnaire. Results: Most 933 (mean [SD] age 65.8 [10.2] years; 55% male; 80% retired) included study received care...
Objectives: This study aimed to provide early insights into sacubitril/valsartan (sac/val) prescription patterns and the demographic clinical characteristics of patients prescribed sac/val in primary care cardiology settings Germany.Methods: The used electronic medical records from German IMS® Disease Analyzer database. Patients with ≥1 for during 1 January–31 December 2016 (n = 1643) were identified followed up ≤12 months first prescription. heart failure (HF) diagnosis period, additional...
To evaluate the cost-effectiveness of vildagliptin plus metformin vs generic sulphonylurea in patients with type 2 diabetes mellitus, not controlled metformin, from a Portuguese healthcare system perspective.A model was constructed using risk equations UK Prospective Diabetes Study Outcomes Model 10,000-patient cohort and lifetime horizon. The predicted microvascular macrovascular complications mortality yearly cycles. Patients entered as monotherapy failures switched to alternative...
Familial chylomicronemia syndrome (FCS) is a rare genetic disorder characterized by deficiency of lipoprotein lipase, causing accumulation chylomicrons. An estimated 0.1-0.2 per 100,000 people has FCS worldwide. patients present massively elevated triglyceride levels (typically >2,000 mg/dL), resulting in increased risk recurring acute pancreatitis. Standard lowering medications are ineffective for patients, who rely on restrictive low fat diet to control their triglyceride. There limited...
The objective of this study was to describe the clinical care pathways, management and treatment patterns, hospitalizations for patients with heart failure (HF) in China.A cross-sectional survey cardiologists their HF conducted. Patient record forms were completed by 150 10 consecutive patients. Patients whom a patient form invited complete self-completion questionnaire.Most 1,500 (mean [SD] age 66 [10] years; 55% male) included received tier-2 -3 hospitals large cities. Cardiologists...
Background: Acute myeloid leukemia (AML) is a heterogeneous disease in terms of clinical features, outcomes and genetics. While mutations NPM1 are usually considered as favorable prognostic marker, the vast majority patients carry several co-mutations that might influence prognosis. Therefore, better understanding NPM1mut AML mutational landscape warranted. The large cohort collected within European HARMONY Alliance provides an excellent basis for this purpose. Aims: To identify clinically...
We examined characteristics of early sacubitril/valsartan users in a large US electronic health records database.We identified three cohorts patients with heart failure (HF): prior HF diagnosis; reduced ejection fraction; and treated an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker β-blocker.Sacubitril/valsartan were younger than the other cohorts; mean age increased by 2 years first 15 months marketing. Most had use treatment.Overall, resembled those fraction...
Bronchiectasis (BE) is characterised by permanent dilation of bronchi with destruction elastic and muscular components their walls. Prophylactic antibiotic treatment acute management exacerbation episodes an important component treatment. Currently there are no approved therapies for BE inhaled antibiotics nebulized solutions used off-label. The objective this study was to predict clinical economic consequences associated in adult patients over lifetime. We developed a Markov cohort model...