A5003323714- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Primary Care and Health Outcomes
- COVID-19 and Mental Health
- Organ Donation and Transplantation
- Sodium Intake and Health
- Nematode management and characterization studies
- Advanced Causal Inference Techniques
- Palliative Care and End-of-Life Issues
- Health Policy Implementation Science
- Child Nutrition and Feeding Issues
- Obesity and Health Practices
- Nutritional Studies and Diet
- Parkinson's Disease Mechanisms and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pharmaceutical Practices and Patient Outcomes
- Obesity, Physical Activity, Diet
- COVID-19 Impact on Reproduction
- Grief, Bereavement, and Mental Health
- COVID-19 Clinical Research Studies
- Cardiac Health and Mental Health
- Cystic Fibrosis Research Advances
Duke-NUS Medical School
2019-2024
Novartis (India)
2013
Background The SingHypertension primary care clinic intervention, which consisted of clinician training in hypertension management, subsidized single‐pill combination medications, nurse‐delivered motivational conversations and telephone follow‐ups, improved blood pressure control cardiovascular disease (CVD) risk scores relative to usual among patients with uncontrolled Singapore. This study quantified the incremental cost‐effectiveness, terms cost per unit reduction disability‐adjusted life...
Background Despite availability of clinical practice guidelines for hypertension management, blood pressure (BP) control remains sub-optimal (<30%) even in high-income countries. This study aims to assess the effectiveness a potentially scalable multicomponent intervention integrated into primary care system compared usual on BP control. Methods and findings A cluster-randomized controlled trial was conducted 8 government clinics Singapore. The enrolled 916 patients aged ≥40 years with...
The coronavirus disease 2019 (COVID-19) pandemic has caused significant psychological distress globally. Our study assessed the prevalence of and associated factors during COVID-19 among kidney transplant recipients donors.
Abstract Identification of hypertensive patients with pre‐diabetes or diabetes is important for timely prevention complications including vascular disease. We aimed to compare the association and discrimination central obesity measures (waist circumference [WC] waist‐to‐height ratio [WHtR]) generalized measure (body mass index [BMI]) in relation among a group Asian first time. used baseline data 925 subjects aged 40 years older uncontrolled hypertension recruited at eight primary care...
Abstract Introduction Cardiovascular disease remains the leading cause of death in Singapore. Uncontrolled hypertension confers highest attributable risk CVD and a significant public health issue with sub-optimal blood pressure (BP) control rates. The aim trial is to evaluate effectiveness cost-effectiveness multicomponent intervention (MCI) versus usual care on lowering BP among adults uncontrolled visiting primary clinics This article describes statistical analysis plan for secondary...
Hypertension is a major public health challenge, globally. Recently, we reported findings from cluster randomized trial in 8 primary care clinics Singapore and showed that multicomponent "SingHypertension" intervention comprising 1) motivational conversation by trained nurses, 2) telephone-based follow-ups, 3) standardized algorithm with single-pill combination (SPC) antihypertensive medications, 4) subsidy on SPC drugs was effective improving BP control. This paper presents the...
Bronchiectasis (BE) is characterised by permanent dilation of bronchi with destruction elastic and muscular components their walls. Prophylactic antibiotic treatment acute management exacerbation episodes an important component treatment. Currently there are no approved therapies for BE inhaled antibiotics nebulized solutions used off-label. The objective this study was to predict clinical economic consequences associated in adult patients over lifetime. We developed a Markov cohort model...
Introduction: Recently the SingHypertension cluster-randomized controlled trial investigated integrating a multicomponent intervention (MCI) into Singapore public sector primary care clinics for patients with uncontrolled hypertension. MCI consisted of physician training in risk-based treatment, antihypertensive medication subsidies, nurse-delivered motivational conversations and telephone follow-ups. While improved blood pressure control cardiovascular disease (CVD) risk scores relative to...
Effective interventions during the coronavirus disease 2019 (COVID-19) pandemic require an understanding of patients' knowledge and perceptions that influence their behaviour. Our study assessed COVID-19 among kidney transplant recipients donors, hitherto unevaluated.We conducted a cross-sectional survey 325 172 donors between 1 May 2020 30 June 2020. The questionnaire levels COVID-19, sociodemographic data, health status, psychosocial impact precautionary behaviours pandemic.The mean score...
An amendment to this paper has been published and can be accessed via the original article.