A5042975869- Renal Transplantation Outcomes and Treatments
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Impact on Reproduction
- Long-Term Effects of COVID-19
- Organ Donation and Transplantation
- COVID-19 and healthcare impacts
- Organ Transplantation Techniques and Outcomes
- Cytomegalovirus and herpesvirus research
- Renal and Vascular Pathologies
- Mosquito-borne diseases and control
- Renal Diseases and Glomerulopathies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Neurological Complications and Syndromes
- Pharmacological Effects and Toxicity Studies
- Transplantation: Methods and Outcomes
- Immunodeficiency and Autoimmune Disorders
- CNS Lymphoma Diagnosis and Treatment
- Malaria Research and Control
- Virus-based gene therapy research
- Animal Virus Infections Studies
- Pregnancy and Medication Impact
- Cardiac Valve Diseases and Treatments
- Lymphoma Diagnosis and Treatment
- Amyloidosis: Diagnosis, Treatment, Outcomes
SingHealth Duke-NUS Academic Medical Centre
2020-2025
Singapore General Hospital
2019-2025
University of Oxford
2023-2025
Oxford Research Group
2024
Boston University
2023-2024
SingHealth
2020-2023
Duke-NUS Medical School
2020-2023
National University of Singapore
2010-2022
Cherie Le Si Gan, Shimin Jasmine Chung, Quan Yao Ho, Thuan Tong Tan, Ban Hock Ian Tatt Liew, Carolyn Shan-Yeu Tien, Sobhana Thangaraju, Terence Kee. Clin Transplant Res -0001;0:. https://doi.org/10.4285/ctr.24.0045
Background. Kidney biopsy is important to guide the management of allograft dysfunction but has a risk complications. This review aimed determine incidence and factors complications after kidney biopsy. Methods. systematic meta-analysis randomized controlled trials, cohort studies, or case-control studies indexed on PubMed, Embase, Cochrane Central Register Controlled Trials, World Health Organization International Clinical Trials Registry, ClinicalTrials.gov, limited English language, from...
Neurolymphomatosis is a lymphoid malignancy of the peripheral nervous system and its natural history poorly understood.
Dengue virus (DENV), a mosquito-borne pathogen, causes systemic infections. There are no clear guidelines regarding the screening of donor blood is used in endemic countries to prevent transfusion or transplant-associated dengue. DENV has been shown be detected urine samples even when viremia undetectable. We describe an incident dengue where tested negative for but positive viuria resulting transmission our two kidney recipients. Both recipients resolved infection uneventfully, with adverse...
Introduction: Coronavirus Disease 2019 (COVID-19) has significantly affected the way healthcare is delivered in Singapore. Healthcare services such as renal transplantation had to rapidly adjust and meet needs (1) protect patients staff, (2) ramp up, conserve or redeploy resources while (3) ensuring that critical remained operational. This paper aims describe experience of transplant programme at Singapore General Hospital (SGH) responding risks constraints posed by pandemic. Methods...
The coronavirus disease 2019 (COVID-19) pandemic has caused significant psychological distress globally. Our study assessed the prevalence of and associated factors during COVID-19 among kidney transplant recipients donors.
Double-filtration plasmapheresis (DFPP) has been utilized for immunomodulation in kidney transplantation. Anticoagulation is important to maintain circuit patency during DFPP. We aimed compare the efficacy and safety of regional citrate anticoagulation (RCA) with systemic heparin DFPP transplant recipients.A retrospective cohort study was conducted RCA (RCA-DFPP) (Hep-DFPP) among recipients a single tertiary center.A total 112 sessions were performed 23 subjects, which 62 RCA-DFPP 50...
The COVID-19 pandemic is protracted and episodic surges from viral variants continue to place significant strain on healthcare systems. vaccines, antiviral therapy monoclonal antibodies have significantly reduced associated morbidity mortality. Concurrently, telemedicine has gained acceptance as a model of care tool for remote monitoring. These advances allow us safely transit our inpatient-based infected kidney transplant recipients (KTRs) hospital-at-home (HaH) care.KTRs with PCR-proven...
Introduction: Percutaneous renal biopsy remains critical for the workup of allograft dysfunction but is associated with risk bleeding. Prophylactic intravenous desmopressin has been proposed to reduce bleeding in native biopsies, its efficacy transplant population unclear and adverse events such as severe hyponatraemia have reported. Materials Methods: We conducted a single-centre retrospective cohort study involving adult (≥21 years old) recipients impaired function (serum creatinine ≥150...
Abstract Aim Compared to Standard Criteria Donors (SCD), Expanded Donor (ECD) kidneys are associated with poorer outcomes, although pre‐transplant biopsy may mitigate risks. This study assessed 5‐year outcomes of deceased‐donor kidney transplant recipients, comparing recipients ECD allografts evaluated histologically SCD and clinically. Methods is a single‐centre retrospective study. From November 2005 December 2009 (Era 1), donors were clinically for suitability donation. October 2017 2),...
Adenovirus is an important cause of haemorrhagic cystitis in kidney transplant recipients. The optimal treatment for adenovirus-associated (AAHC) unknown. Intravenous cidofovir may be effective, but nephrotoxicity a major concern. use intravesical viral has been reported haematopoietic stem cell recipients and associated with lower risk nephrotoxicity, its not We report the AAHC recipients, along review literature.
We present a case of asymptomatic coronavirus disease 2019 (COVID-19) diagnosed in hemodialysis patient during deceased donor renal transplantation (DDRT) evaluation and discuss the challenges excluding COVID-19 before transplantation. A 50-year-old woman with end-stage secondary to IgA nephropathy on was called up as first waitlist. She screened for based our previously published protocol1 addition chest computed tomography (CT) scan. Our her brother, only household contact, were...
Background: Calcineurin inhibitors are the cornerstone of maintenance immunosuppression after kidney transplant. While studies on predominantly Caucasian populations recommend tacrolimus over cyclosporine, effects Singapore’s local population remain unclear. Objectives: This study aimed to compare impact against cyclosporine post-transplant outcomes in our transplant population. Methods: A single-centre retrospective chart review was conducted ABO- and human leucocyte antigen...
Cardiac evaluation before deceased donor kidney transplant (DDKT) remains a matter of debate. Data on Asian countries and with prolonged waiting times are lacking. This study aimed to assess the outcomes patients referred for DDKT after cardiac at an tertiary center.This single-center retrospective review analyzed who were waitlist placement underwent stress testing between January 2009 December 2015. Patients symptoms excluded. The primary outcome was three-point major adverse...
Abstract Background and Aims Valvular heart disease (VHD) is a risk factor for adverse outcomes in end-stage kidney (ESKD) patients. However, the impact of individual valvular lesions on patients transplant waitlist unclear. This study aims to analyse relationship between different VHD all-cause mortality, determine characteristics stratified by types VHD. Method was single-center retrospective cohort ESKD who were referred placement from May 2008 February 2021 had undergone baseline...