Emily Disler

ORCID: 0000-0002-7602-7088
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About
Contact & Profiles
Research Areas
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Cleft Lip and Palate Research
  • Assisted Reproductive Technology and Twin Pregnancy
  • Endometriosis Research and Treatment
  • Uterine Myomas and Treatments
  • Pluripotent Stem Cells Research
  • Gynecological conditions and treatments
  • Craniofacial Disorders and Treatments
  • CRISPR and Genetic Engineering
  • Renal and related cancers
  • dental development and anomalies
  • Endometrial and Cervical Cancer Treatments
  • Ectopic Pregnancy Diagnosis and Management
  • Intestinal Malrotation and Obstruction Disorders
  • Reproductive System and Pregnancy
  • Congenital Anomalies and Fetal Surgery
  • Tissue Engineering and Regenerative Medicine
  • Tracheal and airway disorders

Tufts University
2024-2025

Boston University
2023-2024

Lahey Medical Center
2024

Brigham and Women's Hospital
2019-2023

Harvard University
2019-2023

Georgetown University
2023

Clinical Research Institute
2023

Duke University
2023

Cornell University
2023

University of North Carolina at Chapel Hill
2023

Objective: To compare 12-month post-treatment health-related quality of life (HR-QoL) and symptom severity (SS) changes among patients with symptomatic uterine fibroids (SUF) not seeking fertility undergo a hysterectomy, abdominal myomectomy (AM), or artery embolization (UAE). Materials Methods: The Comparing Options for Management: Patient-Centered Results Uterine Fibroids (COMPARE-UF) Registry is multi-institutional prospective observational cohort study treated SUF. A subset 1465 women...

10.1089/jwh.2022.0133 article EN Journal of Women s Health 2023-01-13

Abstract Background More than 67% of all embryos transferred in the United States involve frozen-thawed embryos. Progesterone supplementation is necessary medicated cycles to luteinize endometrium and prepare it for implantation, but little data available show if this beneficial true natural cycles. We evaluated use luteal phase progesterone cryopreserved/warmed blastocyst transfers not using an ovulatory trigger. Methods Retrospective cohort study a single academic medical center. studied...

10.1186/s40738-021-00096-5 article EN cc-by Fertility Research and Practice 2021-02-09

Introduction Velopharyngeal insufficiency (VPI) and craniofacial differences can lead to diminished speech swallowing function resulting in communication social challenges throughout childhood. To monitor changes patients' psychosocial health velopharyngeal function, the Pediatric Symptom Checklist (PSC) Insufficiency Effects on Life Outcomes (VELO) survey tools be utilized. This study aimed investigate relationship between VPI quality-of-life outcomes disturbances through a comparative...

10.7759/cureus.69176 article EN Cureus 2024-09-11

Treatment options for premature ovarian insufficiency (POI) are limited to hormone replacement and donor oocytes. A novel induced pluripotent stem cell (iPSC) transplant paradigm in a mouse model has potential translational applications management of POI.Mouse granulosa derived-iPSCS were labelled with green fluorescent protein (GFP) reporter differentiated vitro into Differentiated cells assayed estradiol progesterone secretion by enzyme-linked immunosorbent assays. After...

10.1016/j.ebiom.2023.104715 article EN cc-by-nc-nd EBioMedicine 2023-07-21

(Abstracted from Am J Obstet Gynecol 2023;229(3):275.e1–275.e17) Symptomatic uterine fibroids (UFs) are benign tumors diagnosed in approximately 30% of American women by the age 50 years. UFs can significantly affect quality life (QoL) and have a wide range symptoms severity, including pelvic pressure, dyspareunia, sexual dysfunction, infertility, abnormal bleeding.

10.1097/01.ogx.0001004656.85252.19 article EN Obstetrical & Gynecological Survey 2023-12-01

10.1016/s0002-9378(23)00480-5 article EN American Journal of Obstetrics and Gynecology 2023-08-25

Abstract Many reproductive age women with cancer who receive chemotherapy are exposed to gonadotoxic agents and risk diminished ovarian reserve, sterility, premature menopause. Previously, we reported the derivation of steroidogenic cells from induced pluripotent embryonic stem cells. Derived not only produced hormones, but also displayed markers tissue primordial gametes. Here, describe that human follicular fluid (HFF), when added our cell differentiation system, enhances potential...

10.1101/697532 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2019-07-10

Abstract Background: More than 67% of all embryos transferred in the United States involve frozen-thawed embryos. Progesterone supplementation is necessary medicated cycles order to luteinize endometrium and prepare it for implantation, but little data available if this true natural cycles. We evaluated use luteal phase progesterone cryopreserved/warmed blastocyst transfers not using an ovulatory trigger. Methods: Retrospective cohort study a single academic medical center. studied patients...

10.21203/rs.3.rs-31243/v2 preprint EN cc-by Research Square (Research Square) 2020-10-19

Abstract Background: More than 67% of all embryos transferred in the United States involve frozen-thawed embryos. Progesterone supplementation is necessary medicated cycles order to luteinize endometrium and prepare it for implantation, but little data available if this true natural cycles. We evaluated use progesterone luteal phase cryopreserved/warmed blastocyst transfers not using an ovulatory trigger. Methods: Retrospective cohort study a single academic medical center. studied beginning...

10.21203/rs.3.rs-31243/v1 preprint EN cc-by Research Square (Research Square) 2020-05-29

Abstract Background: More than 67% of all embryos transferred in the United States involve frozen-thawed embryos. Progesterone supplementation is necessary medicated cycles to luteinize endometrium and prepare it for implantation, but little data available show if this beneficial true natural cycles. We evaluated use luteal phase progesterone cryopreserved/warmed blastocyst transfers not using an ovulatory trigger. Methods: Retrospective cohort study a single academic medical center. studied...

10.21203/rs.3.rs-31243/v3 preprint EN cc-by Research Square (Research Square) 2021-02-11
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