- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Acute Myocardial Infarction Research
- Cardiac Structural Anomalies and Repair
- Trauma and Emergency Care Studies
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Coronary Interventions and Diagnostics
- Clinical practice guidelines implementation
- Palliative Care and End-of-Life Issues
- Emergency and Acute Care Studies
- Healthcare cost, quality, practices
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Trauma Management and Diagnosis
- Cardiac pacing and defibrillation studies
- COVID-19 and healthcare impacts
- Liver Disease Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac tumors and thrombi
- Liver Disease and Transplantation
- Fuel Cells and Related Materials
University of Göttingen
1995-2024
Universitätsmedizin Göttingen
1989-2024
St. Bernward Krankenhaus
2013-2023
German Red Cross
2018
Ludwig-Maximilians-Universität München
2018
Resuscitation Council
2018
TU Dresden
2005
Johnson & Johnson (United States)
1994
The aim of this study was to investigate the effect contact-to-balloon time on mortality in ST-segment elevation myocardial infarction (STEMI) patients with and without haemodynamic instability. Using data from prospective, multicentre Feedback Intervention Treatment Times ST-Elevation Myocardial Infarction (FITT-STEMI) trial, we assessed prognostic relevance first medical n = 12 675 STEMI who used emergency service transportation were treated primary percutaneous coronary intervention...
Abstract Aims To assess the impact of lockdown due to coronavirus disease 2019 (COVID-19) on key quality indicators for treatment ST-segment elevation myocardial infarction (STEMI) patients. Methods Data were obtained from 41 hospitals participating in prospective Feedback Intervention and Treatment Times ST-Elevation Myocardial Infarction (FITT-STEMI) study, including 15,800 patients treated acute STEMI January 2017 end March 2020. Results There was a 12.6% decrease total number at peak...
A retrospective analysis is presented of data from 17 patients with proven pulmonary embolism (10 women, 7 men, mean age 50.8 [18-76] years) who had received short-term high dosage thrombolytic therapy shortly before or after (less than 24 h) undergoing mechanical resuscitation. The duration resuscitation was 76 (20-160) minutes. Two already been resuscitated half an hour and one hour, respectively, the commencement thrombolysis. In nine other thrombolysis commenced during Hospital mortality...
In patients with ST-segment elevation myocardial infarction (STEMI), it is unknown how patient delay modulates the beneficial effects of timely reperfusion.
BACKGROUND In ST-segment-elevation myocardial infarction (STEMI), a concomitant chronic total occlusion (CTO) in non-infarct-related artery (NIRA) is associated with adverse outcome. the case of infarct-related (IRA) as donor vessel for collaterals to CTO, IRA may lead an acute threat both immediate and collaterally supplied CTO area, which has been described double-jeopardy effect. METHODS AND RESULTS We investigated role preformed intercoronary originating from either or NIRA. Data were...
The aim of this study was to assess the risk intra-aortic balloon counterpulsation and identify clinical procedural variables that would predict complications.We analysed 381 consecutive patients who were treated between 1977 1995 at our catheterization laboratory and/or medical intensive care unit. complications considered relevant limb ischaemia requiring catheter removal, vascular injury, bleeding transfusion, embolic events, infection. In eight could not be inserted. rate for remaining...
Abstract Aims Current European Society of Cardiology guidelines state that repetitive monitoring and feedback should be implemented for ST-elevation myocardial infarction (STEMI) treatment, but no evidence is available supporting this recommendation. We aimed to analyze the long-term effects a formalized data assessment systematic on performance mortality within prospective, multicenter Feedback Intervention Treatment Times in STEMI (FITT-STEMI) study. Methods Regular interactive sessions...
In ST-segment elevation myocardial infarction (STEMI) patients treated with percutaneous coronary intervention, direct transport from the scene to catheterisation laboratory bypassing emergency department has been shown shorten times reperfusion. The aim of this study was investigate effects bypass on mortality in both haemodynamically stable and unstable STEMI patients.The analysis is based a large cohort prospectively included German multicentre Feedback Intervention Treatment Times...
During ventricular fibrillation, myocardial hemodynamic and metabolic effects of percutaneous cardiopulmonary support (PCPS) were analyzed in 11 adult sheep (body weight 77-112 kg). supported an abrupt increase left-ventricular pressures with alignment to aortic was observed 2 animals, which probably due spontaneous regurgitation, resulted deterioration coronary perfusion. In 9 rose from 22.9 ± 4.9 31.2 7.9 mm Hg elevating left wall stress 16,750 8,745 28,835 8,892 dyn/cm2 after 10 min...
Abstract Background Pre-hospital heparin administration has been reported to improve prognosis in patients with out-of-hospital cardiac arrest (OHCA). This beneficial effect may be limited the subgroup of ST-segment elevation myocardial infarction (STEMI) patients. Methods To assess impact pre-hospital loading on TIMI (Thrombolysis Myocardial Infarction) flow grade and mortality STEMI OHCA, we analyzed data from 2,566 consecutive two hospitals participating prospective Feedback Intervention...