A5016608730- Diet and metabolism studies
- Adipose Tissue and Metabolism
- Antioxidant Activity and Oxidative Stress
- Diet, Metabolism, and Disease
- Mitochondrial Function and Pathology
- Nanomaterials for catalytic reactions
- Food composition and properties
- Biochemical Acid Research Studies
- Genomics, phytochemicals, and oxidative stress
- Exercise and Physiological Responses
- Nutritional Studies and Diet
- Copper-based nanomaterials and applications
- Muscle metabolism and nutrition
- Cancer, Lipids, and Metabolism
- Metabolomics and Mass Spectrometry Studies
- Biochemical Analysis and Sensing Techniques
- Cardiovascular Disease and Adiposity
- Catalytic Processes in Materials Science
- Natural product bioactivities and synthesis
- Graphene research and applications
- Parathyroid Disorders and Treatments
- Liver Disease Diagnosis and Treatment
- Free Radicals and Antioxidants
- Parkinson's Disease Mechanisms and Treatments
- Reproductive Biology and Fertility
Nanjing Medical University
2011-2025
Jiangsu Cancer Hospital
2022-2025
Jiangsu Province Hospital
2011-2024
Jilin Agricultural University
2018-2024
State Ethnic Affairs Commission
2024
Changzhou No.2 People's Hospital
2021-2024
Children's Hospital of Fudan University
2024
Shanghai Children's Medical Center
2024
Huaian First People’s Hospital
2022-2023
Suzhou Municipal Hospital
2022-2023
To understand better the cell and molecular basis for epidemiologic association between cigarette smoke, oxidant injury, age-associated macular degeneration, authors examined effects of acrolein, a major toxicant in on oxidative mitochondrial damage retinal pigment epithelial (RPE) cells reduction this by lipoic acid.Cultured human ARPE19 primary cultures fetal (hf)RPE were treated with acrolein. The toxicity acrolein protective R-alpha-lipoic acid variety previously described...
A botanical extract (Regrapex-R®) prepared from whole grape (Vitis vinifera) and Polygonum cuspidatum, which contains polyphenols, including flavans, anthocyanins, emodin, resveratrol, exhibited dose-dependent scavenging effects on reactive oxygen species (ROS). The inhibited increases of ROS protein carbonyl in isolated rat liver mitochondria following exposure to 2,2'-azobis (2-amidino propane) dihydrocholoride (AAPH), a potent lipid oxidant generator. antioxidant this were further...
Cancer cells are usually under higher levels of oxidative stress compared to normal cells.
Abstract Hydroxytyrosol (HTS) is a natural polyphenol abundant in olive oil. Increasing evidence indicates HTS has beneficial effect on human health for preventing various diseases. In the present study, we investigated protective effects of acrolein‐induced toxicity retinal pigment epithelial cell line, ARPE‐19, cellular model smoking‐ and age‐related macular degeneration. Acrolein, major component gas phase cigarette smoke also product lipid peroxidation vivo , at 75 μmol/L 24 h caused...
Multidrug resistance (MDR) of tumor cells is a serious obstacle encountered in cancer treatment. In the current study multiple drug‑resistant HepG2/adriamycin (HepG2/ADR) cell line was established and its MDR characterized. Icaritin, an active ingredient isolated from medical plant Herba Epimedium, observed to reverse present model. Icaritin significantly increased intracellular accumulation ADR decreased expression MDR1 gene HepG2/ADR compared with drug‑sensitive HepG2 cells. addition,...
To study the impact of transducer arrays on deep-seated dosimetry radiotherapy with concurrent tumor treating fields (TTFields) for glioblastoma. Firstly, covering style to CIRS-038 phantom was designed simulate "extreme situation": four were attached as a similar that in clinical scene and, meanwhile, assure layer interest surrounded by twelve electrodes (three each array). Then, eight patients undergone glioblastoma selected, and planed dose patient delivered film inside without arrays....