A5091225324- COVID-19 epidemiological studies
- Influenza Virus Research Studies
- Viral Infections and Vectors
- Malaria Research and Control
- Mosquito-borne diseases and control
- COVID-19 Pandemic Impacts
- Vector-borne infectious diseases
- Viral Infections and Outbreaks Research
- Mathematical and Theoretical Epidemiology and Ecology Models
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Data-Driven Disease Surveillance
- Zoonotic diseases and public health
- Evolution and Genetic Dynamics
- Global Maternal and Child Health
- Animal Disease Management and Epidemiology
- Insect Pest Control Strategies
- Grit, Self-Efficacy, and Motivation
- HIV/AIDS Research and Interventions
- Numerical methods for differential equations
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Stability and Controllability of Differential Equations
- Mental Health Research Topics
- Advanced Mathematical Modeling in Engineering
National Institute for Mathematical Sciences
2021-2025
York University
2017-2022
Korea Institute of Science and Technology
2022
Pusan National University
2022
Kyungpook National University
2010-2022
University of Alberta
2022
Fields Institute for Research in Mathematical Sciences
2020
Applied Mathematics (United States)
2020
Hokkaido University
2016-2017
University of Szeged
2012-2016
ObjectivesZika virus has spread internationally through countries in the South Pacific and Americas. The present study aimed to estimate basic reproduction number, R0, of Zika infection as a measurement transmission potential, reanalyzing past epidemic data from Pacific.MethodsIncidence two epidemics, one on Yap Island, Federal State Micronesia 2007 other French Polynesia 2013–2014, were reanalyzed. R0 was estimated early exponential growth rate these epidemics.ResultsThe maximum likelihood...
Abstract Public health interventions have been implemented to mitigate the spread of coronavirus disease 2019 (COVID-19) in Ontario, Canada; however, quantification their effectiveness remains be done and is important determine if some social distancing measures can relaxed without resulting a second wave. We aim equip local public decision- policy-makers with mathematical model-based estimation trend COVID-19 Ontario inform future actions terms outbreak control de-escalation distancing. Our...
The Middle East respiratory syndrome (MERS) associated coronavirus has been imported via travelers into multiple countries around the world. In order to support risk assessment practice, present study aimed devise a novel statistical model quantify country-level of experiencing an importation MERS case.We analyzed arrival time each reported world, i.e., date on which cases entered specific country, was modeled as dependent variable in our analysis. We also used openly accessible data...
Background. An international spread of Zika virus (ZIKV) infection has attracted global attention. ZIKV is conveyed by a mosquito vector, Aedes species, which also acts as the vector species dengue and chikungunya viruses. Methods. Arrival time importation (i.e., at first imported case was diagnosed) in each country collected from publicly available data sources. Employing survival analysis model hazard an inverse function effective distance informed airline transportation network data,...
Abstract Background Understanding social contact patterns is fundamental to the study of infectious disease transmission. However, in South Korea, detailed data have not been publicly available. While global research on has expanded, there remains a critical need for more context-specific Korea. Methods We conducted survey over two distinct weeks covering various time periods, including school vacations and national holidays. Participants provided details such as location, duration,...
Impact of climate change on tick-borne encephalitis (TBE) prevalence in the tick-host enzootic cycle a given region depends how region-specific patterns influence tick population development processes and virus (TBEV) transmission dynamics involving both systemic co-feeding routes. Predicting risk TBEV with projected conditions is essential for planning public health interventions including vaccination programs to mitigate TBE incidence inhabitants travelers. We have previously developed...
Social contact mixing plays a critical role in influencing the transmission routes of infectious diseases. Moreover, quantifying social patterns and their variations rapidly evolving pandemic intervened by changing public health measures is key for retroactive evaluation proactive assessment effectiveness different age- setting-specific interventions. Contact have been used to inform COVID-19 decision-making; but rigorously justified methodology identify developing pandemic, which can be...
Estimating the tick-borne encephalitis (TBE) infection risk under substantial uncertainties of vector abundance, environmental condition and human-tick interaction is important for evidence-informed public health intervention strategies. this computationally challenging since data we observe, i.e., human incidence TBE, only final outcome tick-host transmission tick-human contact processes. The challenge also increases complex TBE virus (TBEV) cycle involves non-systemic route between...
To investigate the optimal control strategy for Plasmodium vivax malaria transmission in Korea.A model with terms using a deterministic system of differential equations is presented, and analyzed mathematically numerically.If cost reducing reproduction rate mosquito population more than that prevention measures to minimize mosquito-human contacts, contacts needs be taken longer time, comparing other situations. More knowledge about actual effectiveness costs intervention would give realistic...
Abstract Background Seasonal influenza poses a significant public health and economic burden, associated with the outcome of infection resulting complications. The true burden disease is difficult to capture due wide range presentation, from asymptomatic cases non-respiratory complications such as cardiovascular events, its seasonal variability. An understanding magnitude annual incidence important support prevention control policy development evaluate impact preventative measures...
In this study, we propose a novel approach that integrates regime-shift detection with mechanistic model to forecast the peak times of seasonal influenza. The key benefit is its ability detect regime shifts from non-epidemic epidemic states, which particularly beneficial year-round presence non-zero Influenza-Like Illness (ILI) data. This integration allows for incorporation external factors trigger onset influenza season-factors models alone might not adequately capture. Applied ILI data...
We introduce a novel approach to inform the re-opening plan followed by postpandemic lockdown integrating stochastic optimization technique with disease transmission model. assess Ontarios plans as case-study. Taking into account uncertainties in contact rates during different phases, we find optimal timing for upcoming phase that maximizes relaxation of social contacts under uncertainties, while not overwhelming health system capacity before arrival effective therapeutics or vaccines.
Public health interventions have been implemented to mitigate the spread of COVID-19 in Ontario, Canada; however, need for adoption further public remains. We aim equip local decision- and policy-makers with mathematical model-based estimates trend Ontario inform necessary additional measures required its control. Our confirm that social distancing helped transmission by reducing daily infection contact rate, but disease probability per remains as high 0.145 effective reproduction number is...
The COVID-19 pandemic has swept the globe, and countries have responded with various intervention policies to prevent its spread. In this study, we aim analyze effectiveness of implemented in South Korea. We use a stochastic individual-based model (IBM) synthetic population simulate spread COVID-19. Using statistical data, make assign sociodemographic attributes each individual. Individuals go about their daily lives based on assigned characteristics, encountering infectors stochastically...
Co-feeding is a mode of pathogen transmission for wide range tick-borne diseases where susceptible ticks can acquire infection from co-feeding with infected on the same hosts. The significance this pathway determined by co-occurrence at different stages in season. Taking into account, we formulate system differential equations tick population dynamics and highly regulated seasonal temperature variations. We examine global model systems, show that two important ecological epidemiological...
Abstract The E/S (exposed/susceptible) ratio is analyzed in the SEIR model. plays a key role understanding epidemic dynamics during 2014–2016 Ebola outbreak Sierra Leone and Guinea. maximum value of occurs immediately before or after time-dependent reproduction number (R t ) equals 1, depending on initial susceptible population ( S (0)). It demonstrated that transmission rate curves corresponding to various incubation periods intersect at single point referred as Cross Point (CP). At this...
Abstract We prove that for the linear scalar delay differential equation with non-negative periodic coefficients of period P > 0, stability threshold trivial solution is , assuming b ( t +1)− a ) does not change its sign. By constructing class explicit examples, we show counter-intuitive result that, in general, r = 0 threshold.