A5085438161- COVID-19 epidemiological studies
- COVID-19 Pandemic Impacts
- Influenza Virus Research Studies
- Travel-related health issues
- Salmonella and Campylobacter epidemiology
- Viral Infections and Vectors
- Viral Infections and Outbreaks Research
- Listeria monocytogenes in Food Safety
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Microtubule and mitosis dynamics
- COVID-19 and Mental Health
- Stochastic processes and statistical mechanics
- Animal Disease Management and Epidemiology
- Food Safety and Hygiene
- Gene Regulatory Network Analysis
- Viral gastroenteritis research and epidemiology
- Receptor Mechanisms and Signaling
- Data-Driven Disease Surveillance
- Mathematical and Theoretical Epidemiology and Ecology Models
- Vibrio bacteria research studies
- Geriatric Care and Nursing Homes
- Fungal and yeast genetics research
- Mental Health Research Topics
- Healthcare Operations and Scheduling Optimization
York University
2019-2024
Fields Institute for Research in Mathematical Sciences
2020-2022
Laboratoire de Mathématiques
2021
Applied Mathematics (United States)
2020
Cleveland State University
2017
Abstract Public health interventions have been implemented to mitigate the spread of coronavirus disease 2019 (COVID-19) in Ontario, Canada; however, quantification their effectiveness remains be done and is important determine if some social distancing measures can relaxed without resulting a second wave. We aim equip local public decision- policy-makers with mathematical model-based estimation trend COVID-19 Ontario inform future actions terms outbreak control de-escalation distancing. Our...
Since the beginning of COVID-19 pandemic, most Canadian provinces have gone through four distinct phases social distancing and enhanced testing. A transmission dynamics model fitted to cumulative case time series data permits us estimate effectiveness interventions implemented in terms contact rate, probability per contact, proportion isolated contacts, detection rate. This allows calculate control reproduction number during different (which gradually decreased less than one). From this, we...
When public health interventions are being loosened after several days of decline in the number coronavirus disease 2019 (COVID-19) cases, it is critical importance to identify potential strategies ease restrictions while mitigating a new wave more transmissible variants concern (VOCs). We estimated necessary enhancements for partial reopening economy avoiding worst consequences outbreak, associated with VOCs.We used transmission dynamics model quantify conditions that combined must meet...
The 2022 FIFA World Cup was the first major multi-continental sporting Mass Gathering Event (MGE) of post COVID-19 era to allow foreign spectators. Such large-scale MGEs can potentially lead outbreaks infectious disease and contribute global dissemination such pathogens. Here we adapt previous work create a generalisable model framework for assessing use control strategies at events, in terms reducing infections hospitalisations. This utilises combination meta-populations based on clusters...
Social contact mixing plays a critical role in influencing the transmission routes of infectious diseases. Moreover, quantifying social patterns and their variations rapidly evolving pandemic intervened by changing public health measures is key for retroactive evaluation proactive assessment effectiveness different age- setting-specific interventions. Contact have been used to inform COVID-19 decision-making; but rigorously justified methodology identify developing pandemic, which can be...
Abstract Background Seasonal influenza poses a significant public health and economic burden, associated with the outcome of infection resulting complications. The true burden disease is difficult to capture due wide range presentation, from asymptomatic cases non-respiratory complications such as cardiovascular events, its seasonal variability. An understanding magnitude annual incidence important support prevention control policy development evaluate impact preventative measures...
Abstract There is a heavy burden associated with influenza including all-cause hospitalization as well severe cardiovascular and cardiorespiratory events. Influenza cardiac events have been linked to multiple biological pathways in human host. To study the contribution of virus infection thrombotic events, we develop dynamic model which incorporates some key elements host immune response, inflammatory blood coagulation. We formulate these systems integrate them into cohesive modelling...
The attack ratio in a subpopulation is defined as the total number of infections over individuals this subpopulation. Using methodology based on an age-stratified transmission dynamics model, we estimated COVID-19 among children (individuals 0-11 years) when large proportion eligible for vaccination (age 12 and above) are vaccinated to contain epidemic subpopulation, or effective herd immunity (with additional physical distancing measures). We describe relationship between children, time...
The elderly, especially those individuals with pre-existing health problems, have been disproportionally at a higher risk during the COVID-19 pandemic. Residents of long-term care facilities gravely affected by pandemic and resident death numbers far above general population. To better understand how infectious diseases such as can spread through facilities, we developed an agent-based simulation tool that uses contact matrix adapted from previous infection control research in these types...
Public health interventions have been implemented to mitigate the spread of COVID-19 in Ontario, Canada; however, need for adoption further public remains. We aim equip local decision- and policy-makers with mathematical model-based estimates trend Ontario inform necessary additional measures required its control. Our confirm that social distancing helped transmission by reducing daily infection contact rate, but disease probability per remains as high 0.145 effective reproduction number is...
Most mass gathering events have been suspended due to the SARS-CoV-2 pandemic. However, with vaccination rollout, whether and how organize some of these arises as part pandemic recovery discussions, this calls for decision support tools. The Hajj, one world's largest religious gatherings, was substantively scaled down in 2020 2021 it is still unclear will take place 2022 subsequent years. Simulating disease transmission dynamics during Hajj season under different conditions can provide...
Abstract The 2022 FIFA World Cup was the first major multi-continental sporting Mass Gathering Event (MGE) of post COVID-19 era to allow foreign spectators. Such large-scale MGEs can potentially lead outbreaks infectious disease and contribute global dissemination such pathogens. Here we adapt previous work create a generalisable model framework for assessing use control strategies at events, in terms reducing infections hospitalisations. This utilises combination meta-populations based on...
We developed a stochastic optimization technology based on COVID-19 transmission dynamics model to determine optimal pathways from lockdown toward reopening with different scales and speeds of mass vaccine rollout in order maximize social economical activities while not overwhelming the health system capacity general, hospitalization beds, intensive care units particular. used Province Ontario, Canada as case study demonstrate methodology decision trees; but our method algorithm are generic...
Abstract Most mass gathering events have been suspended due to the SARS-CoV-2 pandemic. However, with vaccination rollout, whether and how organize some of these arises as part pandemic recovery discussions, this calls for decision support tools. Hajj, one world's largest religious gatherings, was substantively scaled down in 2020 it is still unclear if will take place 2021 sub-sequent years. Considering disease trends conditions pilgrims’ country origin, operational logistical aspects...
Background: Social contact mixing plays a critical role in influencing the transmission routes of infectious diseases. Quantifying social patterns and their variations rapidly evolving pandemic intervened by changing public health measures is key for retroactive evaluation proactive assessment effectiveness different age- setting-specific interventions. Methods: We performed an analysis intervention escalation phase COVID-19 epidemic Ontario, Canada. Specifically, we integrated derived from...
Abstract Most mass gathering events have been suspended due to the SARS-CoV-2 pandemic. However, with vaccination rollout, whether and how organize some of these arises as part pandemic recovery discussions, this calls for decision support tools. Hajj, one world's largest religious gatherings, was substantively scaled down in 2020 it is still unclear if will take place 2021 subsequent years. Considering disease trends conditions pilgrims’ country origin, operational logistical aspects...
Contexte : Lorsque les interventions de santé publique sont assouplies après plusieurs jours baisse du nombre cas maladie à coronavirus 2019 (COVID-19), il est essentiel déterminer stratégies potentielles pour assouplir restrictions tout en atténuant le risque d’une nouvelle vague variants préoccupants plus transmissibles. Nous avons estimé améliorations nécessaires aux une réouverture partielle l’économie évitant pires conséquences éclosion, associées des Méthodes Un modèle dynamique...