- Protease and Inhibitor Mechanisms
- Eicosanoids and Hypertension Pharmacology
- Environmental Conservation and Management
- Cell Adhesion Molecules Research
- Forest Management and Policy
- Blood Pressure and Hypertension Studies
- Cervical Cancer and HPV Research
- Cardiac Fibrosis and Remodeling
- Economic and Environmental Valuation
- Hormonal Regulation and Hypertension
University of Georgia
2023
Resources For The Future
2023
Virgin Care
2019
NIHR Leicester Cardiovascular Biomedical Research Unit
2000
University of Leicester
2000
In the PATHWAY-2 study of resistant hypertension, spironolactone reduced blood pressure substantially more than conventional antihypertensive drugs. We did three substudies to assess mechanisms underlying this superiority and pathogenesis hypertension.PATHWAY-2 was a randomised, double-blind crossover trial done at 14 UK primary secondary care sites in 314 patients with hypertension. Patients were given 12 weeks once daily treatment each placebo, 25-50 mg, bisoprolol 5-10 doxazosin 4-8 mg...
Abstract Preemptive conservation efforts to reduce threats have been credited with precluding the need list some imperiled species under U.S. Endangered Species Act (ESA). Such can result in outcomes where are conserved and regulatory costs associated ESA listing avoided. Yet, extent type of effort involved achieving preclusion from not well understood. We quantified attributes identified as important for 43 whose was attributed efforts, described Federal Register documents that report...
<h3>Aims</h3> While sexual abuse needs to be considered in cases of anogenital warts (AGW) children, Human Papilloma Virus (HPV) may transmitted other ways. The upper age limit presentation with following perinatal infection is uncertain and accepted extend into early childhood, older children being more likely acquire by transmission. Autoinoculation also possible. To our knowledge there are no protocols routinely used for management AGW Primary Care. We conducted a survey see if were...
An important event in the development of atherosclerosis is dependent on vascular smooth muscle (VSM) cell migration through arterial wall. Studies have previously indicated that matrix metalloproteinase-2 (MMP-2) acts to facilitate VSM by degrading basement membrane proteins (e.g. collagen IV, heparan proteoglycan). Angiotensin II (Ang II) and hypertension been strongly implicated pathogenesis atherosclerosis. This study investigated role mechanical strain MMP-2 activity human cells. Human...