Yingchun Zhu

ORCID: 0000-0002-7822-6478
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Research Areas
  • Particle physics theoretical and experimental studies
  • Quantum Chromodynamics and Particle Interactions
  • High-Energy Particle Collisions Research
  • Bone Tissue Engineering Materials
  • Luminescence Properties of Advanced Materials
  • Nanoplatforms for cancer theranostics
  • Dark Matter and Cosmic Phenomena
  • Advanced Photocatalysis Techniques
  • Supercapacitor Materials and Fabrication
  • Mesoporous Materials and Catalysis
  • Advancements in Battery Materials
  • Particle Detector Development and Performance
  • Semiconductor materials and devices
  • Advanced Nanomaterials in Catalysis
  • Radiation Detection and Scintillator Technologies
  • Graphene and Nanomaterials Applications
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical sensors and biosensors
  • Conducting polymers and applications
  • Advanced ceramic materials synthesis
  • Quantum Dots Synthesis And Properties
  • Metal and Thin Film Mechanics
  • Nanoparticle-Based Drug Delivery
  • Nanoparticles: synthesis and applications
  • Porphyrin and Phthalocyanine Chemistry

Shanghai Institute of Ceramics
2016-2025

Chinese Academy of Sciences
2016-2025

University of Chinese Academy of Sciences
2018-2025

Nanjing Normal University
2025

Zhongshan Hospital
2017-2024

Fudan University
2012-2024

Central China Normal University
2024

Ningbo University
2024

Zhongshan Hospital of Xiamen University
2024

Ningbo First Hospital
2018-2023

Abstract Sonodynamic therapy (SDT) is noninvasive and possesses high body‐penetration depth, showing great potential for the treatment of deep‐seated solid tumors. The efficacy SDT, however, limited by widespread hypoxia in Given this, an ultrasound‐activated nanosystem developed integrating ferrate(VI) protoporphyrin IX into biodegradable hollow mesoporous organosilica nanoplatforms, followed assembling a phase‐change material lauric acid. effectively reacts with water as well overexpressed...

10.1002/adfm.201906195 article EN Advanced Functional Materials 2019-10-14

Piezoelectric materials produce charges to directly act on cancer medium or promote the generation of reactive oxygen species (ROS) for novel tumor therapy triggered by sonography. Currently, piezoelectric sonosensitizers are mainly used catalyze ROS band-tilting effect sonodynamic therapy. However, it remains a challenge high piezovoltages overcome bandgap barrier direct charge generation. Herein, Mn-Ti bimetallic organic framework tetragonal nanosheets (MT-MOF TNS) designed sono-piezo...

10.1002/adma.202301784 article EN Advanced Materials 2023-07-11

Carbon nanofibers (CNFs) have important application potential in the field of supercapacitors; however, relatively low specific surface area often leads to a capacitance. Herein, N-doped carbon nanofibers/carbon nanorods (CNFs/CNRs-N) composite with an N-doping level up 8.9 atom % is designed, which shows excellent supercapacitor energy storage performance. CNFs/CNRs-N has three-dimensional porous structure, large area, and huge number active sites. Based on synergy various unique properties...

10.1021/acsaem.4c03006 article EN ACS Applied Energy Materials 2025-01-16

Kicking out cholesterol: The release of guest molecules (cholesterol) included in the pores mesoporous silica is promoted by simultaneous irradiation with UV and visible light. reversible cis–trans photoisomerization azobenzene substituents on pore surface causes a stirring action, which accelerates diffusion from (see picture), thus providing an intelligent controlled-release method.

10.1002/anie.200604850 article EN Angewandte Chemie International Edition 2007-02-13

The initial EROSION study (Effective Anti-Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography-Based Management in Plaque Erosion) demonstrated that patients with acute coronary syndrome caused by plaque erosion might be stabilized aspirin and ticagrelor without stenting for ≤1 month. However, a long-term evaluation of outcomes is lacking. aim this was to assess whether the benefit noninterventional therapy maintained year.Among 53 who completed clinical follow-up,...

10.1161/circinterventions.117.005860 article EN Circulation Cardiovascular Interventions 2017-12-01

This work reports the nanocomposites of graphitic nanofibers (GNFs) and carbon nanotubes (CNTs) as electrode material for supercapacitors. The hybrid CNTs/GNFs was prepared via a synthesis route that involved catalytic chemical vapor deposition (CVD) method. structure morphology can be precisely controlled by adjusting flow rates reactant gases. nest shape entanglement CNTs GNFs which could not only have high conductivity to facilitate ion transmission, but also increase surface area more...

10.1038/s41598-018-27460-8 article EN cc-by Scientific Reports 2018-06-07

Spinal cord injury (SCI) is the main cause of severe damage to central nervous system and leads irreversible tissue loss neurological dysfunction. Ferroptosis a cell death pattern, newly discovered in recent years. an oxidizing induced by small molecules, iron-dependent process caused imbalance between generation degradation lipid reactive oxygen species (ROS) cells. As antioxidant, trehalose can effectively prevent peroxidation. Studies have reported that improve prognosis SCI. However, it...

10.18632/aging.204009 article EN cc-by Aging 2022-04-10

A hole in one: Hollow nanoporous structures are prepared by controlled decomposition–dissolution. The partial thermal decomposition of transition-metal salts forms a metal oxide shell on the surface salt particles. Acid washing removes cores, resulting hollow shells (see picture). This new strategy provides template-free single-source route to structures. Detailed facts importance specialist readers published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or...

10.1002/anie.200900539 article EN Angewandte Chemie International Edition 2009-08-24

Excess reactive oxygen species (ROS) have been proved to damage cancer cells efficiently. ROS overproduction is thus greatly desirable for therapy. To date, production generally uncontrollable and outside cells, which always bring severe side-effects in the vasculature. Since most share a very short half-life primarily react close their site of formation, it would be more efficient if excess are controllably produced inside cells. Herein, we report an lysosome-controlled via pH-responsive...

10.1039/c5nr00706b article EN Nanoscale 2015-01-01

Abstract Diabetic nephropathy (DN) is a kind of microvascular complications diabetes. Long noncoding RNAs (lnRNAs) can participate in the development various diseases, including DN. However, function lncRNA NEAT1 unclear. In our present study, we reported that was significantly increased streptozotocin‐induced DN rat models and high‐glucose‐induced mice mesangial cells. We observed knockdown greatly inhibited renal injury rats. Meanwhile, downregulation NEAT1‐modulated extracellular matrix...

10.1002/jcp.27959 article EN Journal of Cellular Physiology 2018-12-13

Inspired by the restoration of superhydrophobic surfaces after damage in nature such as lotus leaf and clover, smart self-healing coating with controllable release loaded healing agents is both scientific technological interest. Herein, a superhydrophobicity was gained through blending UV/NIR/acid/base multiple-responsive ZnO-encapsulated mesoporous polydopamine (MPDA) microspheres (zinc oxide-encapsulated microspheres) silicone latex hydrophobic nanoparticles. The micro/nanostructured MPDA...

10.1021/acsami.1c15239 article EN ACS Applied Materials & Interfaces 2021-11-22

Tumor microenvironment (TME) plays an important role in the tumor progression. Among TME components, cancer-associated fibroblasts (CAFs) show multiple tumor-promoting effects and can induce immune evasion drug-resistance. Regulating CAFs be a potential strategy to augment systemic anti-tumor immunity. Here, study observes that hydrogen treatment alleviate intracellular reactive oxygen species of reshape CAFs' immune-suppressive phenotypes. Accordingly, controllable TME-responsive therapy...

10.1002/advs.202401269 article EN cc-by Advanced Science 2024-05-17

Large quantities of very thin and wide single-crystal alpha silicon nitride (α-Si3N4) nanobelts were synthesized by a vapor-solid thermal reaction between ammonia monoxide (SiO) without using any added catalyst. Scanning electron microscopy, high-resolution energy dispersive x-ray spectroscopy, diffraction used to characterize the formed nanobelts. The α-Si3N4 are about 800–1200 nm in width, 20–35 thickness several tens hundreds micrometers length. perfect structure. grow along [011] [100]...

10.1063/1.1623940 article EN Applied Physics Letters 2003-10-24

The rapid spread of infectious bacteria has brought great challenges to public health. It is imperative explore effective and environment-friendly antibacterial modality defeat antibiotic-resistant with high biosafety broad-spectrum property.Herein, biocompatible Cu3SnS4 nanoflakes (NFs) were prepared by a facile low-cost fabrication procedure. These NFs could be activated visible light, leading light-mediated photocatalytic generation myriad reactive oxygen species (ROS). Besides, the...

10.1186/s12951-022-01403-y article EN cc-by Journal of Nanobiotechnology 2022-04-20

Metal sulfide-based cathode materials for aqueous zinc ion batteries (AZIBs) suffer from a high Zn2+ diffusion energy barrier and sluggish kinetics issues, leading to poor rate capability cycle...

10.1039/d5ta00183h article EN Journal of Materials Chemistry A 2025-01-01
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