A5071103700- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Bone Metabolism and Diseases
- Bone Tissue Engineering Materials
- Bone health and treatments
- Diet and metabolism studies
- Gut microbiota and health
- Bone and Joint Diseases
- Musculoskeletal synovial abnormalities and treatments
- Sarcoma Diagnosis and Treatment
- Coronary Interventions and Diagnostics
- MicroRNA in disease regulation
- Nanoplatforms for cancer theranostics
- Cervical and Thoracic Myelopathy
- Extracellular vesicles in disease
- Nanoparticle-Based Drug Delivery
- Nutritional Studies and Diet
- Elbow and Forearm Trauma Treatment
- Nutrition and Health in Aging
- Pelvic and Acetabular Injuries
- Immune cells in cancer
- Advanced X-ray and CT Imaging
- Medical Imaging and Analysis
Shanghai Ninth People's Hospital
2008-2024
Shanghai Jiao Tong University
2014-2024
Chinese Academy of Sciences
2008
Trimethylamine-N-oxide (TMAO), an important gut microbiota (GM)-derived metabolite, has been shown to be abnormally increased in osteoporosis. However, the role and underlying mechanism of TMAO regulating bone loss during osteoporosis have not fully investigated. In current study, we found that 100-400 μM dose-dependently enhanced TRAP-positive osteoclasts, F-actin ring formation, resorption area on bovine slices up-regulated osteoclast-related gene expression (Calcr, Traf6, Dcstamp, Acp5,...
In Brief Study Design. Retrospective cohort analysis of prospectively collected data. Objective. To compare clinical outcomes and postoperative complications in patients with lumbar degenerative scoliosis who underwent primary (P) versus revision (R) surgery. Summary Background Data. Revision surgery for spinal deformity is technically challenging may be associated greater risks inferior outcomes. There a paucity data the literature comparing respect to their complications. Methods. An 84...
Retrospective cohort analysis of prospectively collected data.To determine whether an association exists between body mass and surgical outcomes in patients with degenerative scoliosis after long instrumented spinal arthrodesis (≥ 4 discs).Obesity is thought to be associated increased complications inferior clinical adults. There are no studies analyzing the effect obesity on arthrodesis.Eighty-four consecutive (69 females 15 males; mean age, 68.6 ± 8.0 yr) a minimum follow-up 2 years were...
Objective: The purpose of this study was to analyze the feasibility repairing a ruptured intervertebral disc using patch secured inner surface annulus fibrosus (AF). Different material properties and geometries for were evaluated. Methods: Using finite element analysis, created large box-shaped rupture in posterior-lateral region AF then repaired it with circular square patch. elastic modulus patches ranged from 1 50 MPa determine effect on nucleus pulposus (NP) pressure, vertical...
Objective: The objective of the study was to investigate effectiveness applying individualized guide plate which is based on digital image processing and 3D printing technology percutaneous needle biopsy periacetabular tumor. Methods: From July 2017 August 2019, 11 patients (5 males 6 females, aged 13-70 years, mean 42.3 years) with acetabular tumors diagnosed by in our hospital were enrolled this retrospective study. Preoperative CT MRI enhancement examination performed routinely, DICOM...
Isolated traumatic dislocation of the distal and proximal interphalangeal joints fingers is a common occurrence. However, simultaneous double in one finger rare. Here we report case dorsal both little with review literature. (DIP) (PIP) DIP PIP single seems to be rare event. Most these dislocations are secondary high energy sport injuries may accompany volar plate or collateral ligament injury. Routinely, managed closed reduction followed by immobilization for period 2o4 weeks. We here...
Study Design Biomechanical testings and finite element analysis. Objectives This study aims to investigate how annulus fibrosus (AF) incision size (RIS, Ratio of width AF height) shape affect intervertebral disc (IVD) biomechanics. Methods A validated model lumbar spines simulated various incisions in the middle-right posterior region AF, with different sizes shapes. Simulations included axial compression, flexion, extension, bending, rotation. Parameters assessed stability, re-herniation,...
To compare the biomechanical properties of a novel annular incision technique, an oblique made approximately 60° to spinal column, with traditional transverse and longitudinal slit in ex vivo sheep lumbar spine model. Sixteen spines were used for current comparative study. Functional unit (FSU) specimens composed two vertebrae one disc middle was cut from whole spine. Annular incisions 5 mm different directions 15-blade knife at intervertebral disc, following which partial discectomy...
Retrospective cohort study.To determine whether an association exists between high body mass index (BMI>25 kg/m) and surgical outcomes in revision adult scoliosis patients.Obesity is thought to be associated with increased complications inferior clinical adults. There are no studies analyzing the effect of obesity on patients for scoliosis.Forty-five consecutive (35 women 10 men; mean age, 62.7±9.3 y) a minimum follow-up 2 years were included this study. Patients divided into groups...
Abstract Purpose The blood vessel gives key information for pathological changes in a variety of diseases. In view the crucial role structure, present study aims to establish digital human standard model diagnosing vessel-related Methods recruited eight healthy volunteers, and reconstructed their bilateral upper extremity arteries according CTA. vessels were segmented, registered, merged into bunch. After being cut by continuous planes, dispersion bunches on each plane calculated. Results...