A5028452964- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Contact Dermatitis and Allergies
- Dermatology and Skin Diseases
- Acupuncture Treatment Research Studies
- Pneumonia and Respiratory Infections
- Asthma and respiratory diseases
- Dermatologic Treatments and Research
- Complement system in diseases
- Systemic Lupus Erythematosus Research
- Neonatal skin health care
- Cutaneous Melanoma Detection and Management
- Pregnancy and Medication Impact
- Psoriasis: Treatment and Pathogenesis
- Complementary and Alternative Medicine Studies
- RNA regulation and disease
- Entomological Studies and Ecology
- Inflammatory Bowel Disease
- COVID-19 Clinical Research Studies
- Hair Growth and Disorders
- Liver Diseases and Immunity
- Vascular Malformations and Hemangiomas
- Medicine and Dermatology Studies History
- Endoplasmic Reticulum Stress and Disease
- Autoimmune Bullous Skin Diseases
United Christian Hospital
2007-2024
Hospital Authority
2021
Stanford University
2021
Chinese University of Hong Kong
2019
Charles River Associates
2018
Great Ormond Street Hospital
2007
University College London
2007
Objective To report the clinical, laboratory, and radiologic features of children with severe acute respiratory syndrome (SARS) to examine difference between younger older age groups. Design Retrospective descriptive cohort study. Setting A regional hospital in Hong Kong. Patients Children than 18 yrs SARS. Results Twenty-one were included, a mean 10.7 ± 5.1 yrs. SARS presented fever, nonproductive cough, malaise, chills, headache, myalgia, loss appetite. Examination chest showed minimal...
Topical corticosteroids (CSs) are the mainstay of treatment for eczema but CS phobia and fears prevalent influence therapeutic efficacy.To quantify if acceptability fear affect patients' quality-of-life (QoL).Patients with managed in pediatric dermatology outpatient clinic a university hospital were surveyed. Nottingham Eczema Severity Score (NESS) severity, Children's Dermatology Life Quality Index (CDLQI) QoL, fear, reported frequency use measured quantified questions.CS among parents...
Epidermolysis bullosa (EB) is a heterogeneous group of congenital blistering diseases that are usually present in the neonatal period. They characterized by blister formation response to rubbing or frictional trauma. EB classified into three major categories, each with many subtypes based on precise location at which separation occurs, namely epidermolysis simplex (EBS), junctional (JEB), and dystrophic (DEB). We describe causes ages death cases Hong Kong. A 24-year-old male EBD diagnosed...
Anaphylaxis is a significant health burden in most Western countries, but there are little published data on the incidence and pattern of anaphylaxis Asia. We aim to determine rate over past decade among pediatric population Hong Kong.Medical records patients presenting with allergy-related symptoms during period 2010 2019 were examined. Pediatric aged below 18 years who fulfilled diagnostic criteria for laid out by NIAID/FAAN analyzed. Incidence rates calculated using statistics as...
The current diagnostics of fish allergy lack sufficient accuracy such that more reliable tests as component-resolved diagnosis (CRD) are urgently needed. This study aimed at identifying allergens salmon and grass carp evaluating the sensitization pattern in allergic subjects from two distinct populations Asia. One hundred three were recruited Hong Kong (67 subjects) Japan (46 subjects). Western blot mass spectrometry used to identify carp. Fish purified tested against 96 sera on ELISA...
Eczema is a common childhood atopic condition and treatment with emollients, topical corticosteroids, avoidance of possible triggers. S. aureus colonization complication. As there no immediate cure, many parents seek alternative therapies that claim unproven therapeutic efficacy. We report girl long history noncompliance. After practicing period dietary supplementation, the grandparents took her to an medicine practitioner. Following cupping therapy acupuncture, child developed blistering...
There is some evidence to suggest that the prevalence of atopic dermatitis (AD) in Asia rising. We have therefore developed an algorithm for topical treatment AD throughout South and East use by primary care physicians, pediatricians dermatologists. Nine experts from one Europe based upon guidelines, relevant literature local practices. The outlines current best practice emollients, corticosteroids (TCS) calcineurin inhibitors (TCI), with intention simplifying regimen mild-to-moderate Asia....
Fish allergy is a significant health concern, with diagnosis and management complicated by diverse fish species allergens. We conducted comprehensive RNA-seq analysis of eight to identify allergen profiles, integrating ImmunoCAP sIgE data explore associations expression diagnostic performance. Over 30 putative allergens were identified, varying sequence similarities levels, roughly classifying into two groups based on parvalbumin (PV) expression. Higher in correlated stronger relationships...
Real-world Sensitization and Tolerance Pattern to Seafood inFish-Allergic Individuals Fish-allergic patients N=249By history sensitization (70%) By oral food challenge (30%)Selectively tolerant ≥ one fish, N=100 Shellfish co-sensitization, N=130 IgE levels fish extracts among 249 fish-allergic individuals Cod Halibut Salmon Tuna Grouper Herring Tilapia Catfish Grass carp P a r v l b u m i n T o e c An gradient clinical tolerance pattern corresponded the of parvalbumin in fish0% 10% 20% 30%...
Abstract Background Studies on the relationship between childhood allergic disease and health‐related quality of life (HRQOL) have mostly been confined to a single condition. Therefore, composite score (CAS) was derived assess accumulated effect eczema, asthma, rhinitis HRQOL in Hong Kong schoolchildren. Methods Parents grade one/two or eight/nine schoolchildren completed questionnaire assessing prevalence severity eczema (POEM), asthma (C‐ACT/ACT), (VAS) schoolchildren's (PedsQL). Three...
Vanishing white matter disease is a rare neurological disease. The majority of patients reported are Caucasian individuals. We describe the first Chinese patient with typical clinical and radiological features genetically confirmed to have vanishing for mutation in EIF2B4, followed by brief review
Background The current diagnostics of fish allergy lack sufficient accuracy such that more reliable tests as component-resolved diagnosis (CRD) are urgently needed. This study aimed at identifying allergens salmon and grass carp evaluating the sensitization pattern towards identified in allergic subjects from two distinct populations Asia. Methods One hundred three were recruited Hong Kong (67 subjects) Japan (46 subjects). Western blot mass spectrometry used to identify carp. Fish purified...
Due to the increasing incidences of malignant melanoma, there is a rising demand for assistive technologies its early diagnosis and improving survival rate. The commonly used visual screening method with limited accuracy as phase melanoma shares many clinical features an atypical nevus, while conventional dermoscopes are not user-friendly in terms setup time operations. Therefore, development intelligent handy system assist accurate long-term monitoring melanocytic skin lesions crucial...