A5028387011- Intensive Care Unit Cognitive Disorders
- Frailty in Older Adults
- Family and Patient Care in Intensive Care Units
- Long-Term Effects of COVID-19
- Sepsis Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Respiratory Support and Mechanisms
- Hip and Femur Fractures
- Healthcare professionals’ stress and burnout
- Cardiac, Anesthesia and Surgical Outcomes
- Vitamin K Research Studies
- Anesthesia and Neurotoxicity Research
- COVID-19 and Mental Health
- Maternal Mental Health During Pregnancy and Postpartum
- Health Systems, Economic Evaluations, Quality of Life
- Nursing education and management
- Geriatric Care and Nursing Homes
- Family Caregiving in Mental Illness
- Anesthesia and Sedative Agents
- Vitamin C and Antioxidants Research
- Health and Well-being Studies
- Lipoproteins and Cardiovascular Health
- Inflammasome and immune disorders
- Infant Development and Preterm Care
Ziekenhuis Bernhoven
2020-2024
Radboud University Nijmegen
2023
Radboud University Medical Center
2023
<h3>Importance</h3> One-year outcomes in patients who have had COVID-19 and received treatment the intensive care unit (ICU) are unknown. <h3>Objective</h3> To assess occurrence of physical, mental, cognitive symptoms among with at 1 year after ICU treatment. <h3>Design, Setting, Participants</h3> An exploratory prospective multicenter cohort study conducted ICUs 11 Dutch hospitals. Patients (N = 452) COVID-19, aged 16 years older, alive hospital discharge following admission to during first...
Rationale: Comprehensive studies addressing the incidence of physical, mental, and cognitive problems after ICU admission are lacking. With an increasing number survivors, improved understanding post-ICU is necessary. Objectives: To determine occurrence cooccurrence new among survivors 1 year admission, their impact on daily functioning, risk factors associated with 1-year outcomes. Methods: Prospective multicenter cohort study, including patients ⩾16 years age, admitted for ⩾12 hours...
A subset of critically ill COVID-19 patients develop a hyperinflammatory state. Anakinra, recombinant interleukin-1 receptor antagonist, is known to be effective in several diseases. We investigated the effects anakinra on inflammatory parameters and clinical outcomes ill, mechanically ventilated with features hyperinflammation.In this prospective cohort study, 21 treated were compared group standard care. Serial data concentrations multiple circulating cytokines determined aligned start day...
Long-term mental outcomes in family members of coronavirus disease 2019 (COVID-19) intensive care unit (ICU) survivors are unknown. Therefore, we assessed the prevalence health symptoms, including associated risk factors, and quality life (QoL) COVID-19 ICU 3 12 months post-ICU.A prospective multicentre cohort study ICUs ten Dutch hospitals, adult admitted between March 1, July 2020. Symptom rates anxiety, depression (Hospital Anxiety Depression Scale) Post-Traumatic Stress Disorder (Impact...
Rationale: Delirium is common in critically ill patients and associated with deleterious outcomes. Nonpharmacological interventions are recommended current delirium guidelines, but their effects have not been unequivocally established. Objectives: To determine the of a multicomponent nursing intervention program on ICU. Methods: A stepped-wedge cluster-randomized controlled trial was conducted ICUs 10 centers. Adult surgical, medical, or trauma at high risk developing were included. focusing...
With survival rates of critical illness increasing, quality life measures are becoming an important outcome ICU treatment. Therefore, to study the impact on life, we explored before and 1 year after admission in different subgroups survivors.
Objectives: Although patient’s health status before ICU admission is the most important predictor for long-term outcomes, it often not taken into account, potentially overestimating attributable effects of critical illness. Studies that did assess pre-ICU included specific patient groups or assessed one domain. Our aim was to explore physical, mental, and cognitive functioning, as well their quality life admission. Design: Baseline data were used from longitudinal prospective MONITOR-IC...
To develop and externally validate a prediction model for ICU survivors' change in quality of life 1 year after admission that can support physicians preparing patients managing their expectations.Data from prospective multicenter cohort study (MONITOR-IC) were used.Seven hospitals the Netherlands.ICU survivors greater than or equal to 16 years old.None.Outcome was defined as life, measured using EuroQol 5D questionnaire. The developed based on data an academic hospital, multivariable linear...
To determine the effect of a standardized program for family participation in essential care activities ICU on symptoms anxiety, depression, posttraumatic stress and satisfaction among relatives, perceptions experiences healthcare providers (HCPs).
To determine differences in one-year multi-domain health outcomes COVID-19 and non-COVID-19 intensive care unit (ICU) survivors. Adult ICU survivors treated for were compared to a control group consisting of admitted respiratory distress due other causes, i.e. ARDS or pneumonia. Occurrence physical (frailty, fatigue, symptoms), mental (anxiety, depression, post-traumatic stress) cognitive symptoms, quality life (QoL) scores measured, using validated questionnaires, before one year after...
Rationale: Despite functional impairments, intensive care unit (ICU) survivors can perceive their quality of life as acceptable. Objectives: To investigate discrepancies between calculated health, based on self-reported physical, mental, and cognitive functioning perceived 1 year after ICU admission. Methods: Data from an ongoing prospective multicenter cohort study, MONITOR-IC, were used. Patient-reported health (EuroQol visual analog scale; range, 0-100) post-ICU patients admitted to 11...
OBJECTIVES: To explore associations between the physical, cognitive, and mental post-intensive care syndrome (PICS) health domains with changes in health-related quality of life (HRQoL) following ICU admission. DESIGN: A longitudinal prospective multicenter cohort study. SETTING/PATIENTS: Patients ( n = 4092) from seven Dutch ICUs. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: At admission, 3 12 months post-ICU, patients completed validated questionnaires regarding physical problems,...