- Liver Disease Diagnosis and Treatment
- MRI in cancer diagnosis
- Effects and risks of endocrine disrupting chemicals
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Pesticide and Herbicide Environmental Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Pesticide Exposure and Toxicity
- MicroRNA in disease regulation
- Anesthesia and Neurotoxicity Research
- Radiomics and Machine Learning in Medical Imaging
- Carcinogens and Genotoxicity Assessment
- Drug-Induced Hepatotoxicity and Protection
- Advanced MRI Techniques and Applications
- Organ Transplantation Techniques and Outcomes
- Sperm and Testicular Function
- Genomics, phytochemicals, and oxidative stress
- Per- and polyfluoroalkyl substances research
- Trace Elements in Health
- Ocular Oncology and Treatments
- Brain Metastases and Treatment
- Liver Disease and Transplantation
- Vasculitis and related conditions
- Pharmacological Effects of Natural Compounds
- Ginseng Biological Effects and Applications
Southeast University
2022-2025
Weihai Chest Hospital
2019-2024
Weihai Municipal Hospital
2024
Qingdao University
2018-2024
Nanjing Medical University
2016-2023
Tianjin Medical University
2021-2022
Tianjin First Center Hospital
2022
Southeast University
2022
Nankai University
2022
Affiliated Hospital of Qingdao University
2018
People are continually and simultaneously exposed to various non-persistent pesticides as these chemicals ubiquitously distributed in the environment. Toxicological studies have indicated associations between liver fibrosis vitro vivo. However, epidemical study on deleterious effect of risk is rather limited. To examine relationship mixed exposure fibrosis, identify potential significant importance, this enrolled representative individuals from NHANES 2013-2016 survey cycles, which urinary...
We investigated the relation between non-persistent pesticides and hypertension using data from 4260 adults in NHANES (2007-2014). Urinary concentrations of biomarkers for were served as level pesticide exposure. The prevalence was 42.6%. weighted logistic regression revealed a significant positive association para-nitrophenol (PNP) (OR: 1.11, 95% CI: 1.03-1.20, p = 0.010), while 3,5,6-trichloropyridinol (TCPY), 3-phenoxybenzoic acid (3-PBA) 2,4-dichlorophenoxyacetic (2,4-D) showed no with...
Objective: To investigate the potential of diffusion kurtosis imaging (DKI) in monitoring improvement liver and kidney injury cirrhotic rats after bone marrow derived mesenchymal stem cells (BMSCs) treatment. Methods: Thirty were induced with cirrhosis via subcutaneous injection carbon tetrachloride. Six randomly selected for DKI scanning subsequently euthanized biochemical histological analysis. The remaining 24 divided into a BMSC group (n=12) control (n=12). In group, six underwent...
Objective To investigate the acute effect of air pollutants on ischaemic stroke (IS) and IS-related death. Setting Five urban districts in Changzhou, China, between 9 January 2015 31 December 2016. Participants A total 32 840 IS cases 4028 deaths were enrolled. Main outcome measures time-series design, generalised additive model multivariable regression used to examine percentage change (95% CI) daily counts with an IQR increase pollutant levels for different single or multiple lag days...
An abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. We identified plasma insulin-like growth factor 1 (IGF1) as an independent risk in patients with AAA by correlating IGF1 risk. Smooth muscle cell- or fibroblast-specific knockout of
Serum creatinine (Scr) may be not suited to timely and accurately reflect kidney injury related chronic liver disease. Currently, the ability of arterial spin labeling (ASL) blood oxygen level-dependent (BOLD) sequences evaluate renal flow (RBF) in disease remains verified.
Glyphosate is the most commonly used herbicide with potential neurotoxicity. However, limited epidemical evidence found in relationship between glyphosate and cognitive impairment, especially cognitive-disrupting sensitive elderly populations.
Widespread glyphosate contamination in the environment and its endocrine-disrupting potential are concerning. However, evidence of glyphosate's effects on glycemic health is limited. To examine association between glucose homeostasis general US population, a total 3038 individuals were enrolled from 2013-2016 cycles National Health Nutrition Examination Survey (NHANES). Survey-weighted linear regression restricted cubic spline curves used to detect associations disorders. The interactions...
The potential beneficial effect of ozone (O₃) on stroke had been identified experimentally and clinically, but these effects remain controversial in population-based studies. This study aimed to explore the epidemiological association between O₃ risk ischemic stroke. Ischemic related health data air pollution were obtained from Center for Disease Control Prevention Environmental Monitoring Changzhou 2015 2016, respectively. associations short-term exposure daily onsets deaths examined based...
Abstract Cytochrome P450 3A (CYP3A) is the most abundant CYP450 enzyme in liver and involved metabolism of over 50% xenobiotics. Our previous studies revealed that 2,2′,4,4′-tetrabromodiphenyl ether (BDE47) could induce rat CYP3A1 expression, but molecular basis remains unclear. Using silico analysis, we identified a potential miR-23b recognition element (MRE23b) 3′-UTR region mRNA, which was verified by luciferase assay. The mimic inhibitor significantly down- up-regulated expression...
Fenvalerate (FEN), a mainstream pyrethroid pesticide, was initially recommended as low-toxicity agent for controlling agricultural and domestic pests. Despite the widespread use of FEN worldwide, little data are available on FEN-induced hepatic lesions molecular mechanisms. In present study, we first performed an occupational cross-sectional study factory workers found that levels serum alanine aminotransferase (ALT) total antioxidant capacity increased, whereas malondialdehyde decreased in...