A5069936988- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Urologic and reproductive health conditions
- Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Renal cell carcinoma treatment
- Hormonal and reproductive studies
- Testicular diseases and treatments
- Multiple and Secondary Primary Cancers
- Epigenetics and DNA Methylation
- Vascular Malformations and Hemangiomas
- Urinary Tract Infections Management
- Genital Health and Disease
- Cancer, Lipids, and Metabolism
- Urinary Bladder and Prostate Research
- Identification and Quantification in Food
- Historical and Environmental Studies
- Male Breast Health Studies
- Genetic and Kidney Cyst Diseases
- Infectious Disease Case Reports and Treatments
- Breast Cancer Treatment Studies
- Mercury impact and mitigation studies
Istituto Zooprofilattico Sperimentale Della Sicilia
2021-2023
University of Palermo
2004-2021
Tumori Foundation
2013
ANT Foundation Italy Onlus
2013
Gruppo Italiano per lo Studio dei Carcinomi dell’Apparato Digerente
2009
University of Palermo
2009
BACKGROUND Phytotherapy has been used to treat patients with lower urinary tract symptoms (LUTS). We evaluated the efficacy and tolerability of combination therapy between Serenoa Repens (SeR), Lycopene (Ly), Selenium (Se) + tamsulosin versus single therapies. METHODS PROCOMB trial (ISRCTN78639965) was a randomized double‐blinded, double‐dummy multicenter study 225 55 80 years old, PSA ≤ 4 ng/ml, IPSS ≥12, prostate volume ≤60 cc, Qmax ≤15 ml/sec, postvoid residual urine (PVR) <150 ml....
Study Type – Therapy (RCT) Level of Evidence 1b OBJECTIVE To evaluate the efficacy 1‐year maintenance after a 6‐week cycle early intravesical chemotherapy, as role in chemotherapy is debated. PATIENTS AND METHODS Between May 2002 and August 2003, 577 patients with non‐muscle‐invasive bladder cancer (NMI‐BC) underwent transurethral resection (TUR) (epirubicin, 80 mg/50 mL). They were randomized between induction plus 10 monthly instillations. In all, 95 T1G3, Tis or single primary Ta–T1 G1–G2...
A risk assessment, related to the consumption of farmed sea bass, was carried out by meta-analysis, taking into account concentration trace metals (Cd, Pb, Hg) reported in literature, estimated weekly intake (EWI), provisional tolerable (PTWI), and target hazard quotient (THQ). The concentrations Cd, Hg bass marketed Sicily (Southern Italy) were also assessed inductively coupled plasma mass spectrometry (ICP-MS) atomic absorption spectroscopy (AAS) have screening data for comparison with...
<i>Objective:</i> The distribution of potential environmental risk factors among patients affected by superficial transitional cell carcinoma the bladder (TCCB) has been analyzed. <i>Methods:</i> Patients TCCB underwent TUR and early intravesical chemotherapy. Detailed data about age, sex, residence, employment, active passive cigarette smoking, water resource hair dye use were centralized. Analysis conducted on 474 Ta-T1 G1-2 at medium for recurrence. with primary...
In the absence of Tis tumor we assessed whether history and multiplicity have a detrimental effect on conservative treatment in carefully selected patients with T1G3 bladder carcinoma.Between January 1976 December 1999, 165 select tumors were conservatively treated transurethral resection plus adjuvant intravesical therapy. Patients concomitant or previous Tis, T1G3, size greater than 3 cm more lesions excluded from analysis. Repeat was not routinely performed. However, cytology had to be...
<i>Objectives:</i> To investigate the safety and efficacy in terms of PSA response a low-dose oral combination estramustine phosphate (EMP) etoposide (VP16) hormone- refractory prostate cancer (HRPC) patients. Well-tolerated outpatient chemotherapy regimens for patients unfit and/or unwilling to be admitted hospital are needed. <i>Methods:</i> Fifty-six HRPC with metastatic disease (median age 75 years) were randomized between arm A (daily EMP 10 mg/kg, 3 doses) B...
<i>Objective:</i> Water source and cigarette smoking are related to clinical characteristics pathology of superficial transitional cell carcinoma the bladder. <i>Methods:</i> Tumor number, dimension, G-grade, T-stage, recurrences, water supply were recorded in patients harboring Ta–T1 G1–3 <i>Results:</i> Of 577 patients, 61% had multiple 36% recurrent tumors. Two hundred forty-one (42%) current smokers 188 (33%) former smokers. Bottled was only drinkable...
Introduction Toxicity is a major problem for patients undergoing intravesical therapy with Bacillus Calmette-Guérin (BCG) the conservative management of intermediate or high-risk non-muscle invasive bladder cancer (NMI-BC). A prospective pilot trial was designed to evaluate adoption single dose prulifloxacin prevent toxicity BCG. Treatment tolerability and its possible influence on BCG efficacy have been analyzed. Materials Methods The study action in NMI-BC, 6–week induction cycle Main...
Purpose The purpose of the paper was to know and evaluate consumption, preferences knowledge labelling legislation about wild farmed seafood products. Design/methodology/approach A sample survey on Sicilian families conducted through a direct interviews between October 2015 2016 study attitudes consumers towards fish stratified two-stage sampling design chosen with variable probability inclusion units first stage 1,700 subjects were interviewed. Findings results obtained showed that 69.4%...
Ascending aortic diameter is not an accurate parameter for surgical indication in patients with bicuspid valve (BAV). Thus, the present study aimed to identify specific microRNAs (miRNAs/miRs) and their expression levels wall aneurysm associated BAV according severity of medial degeneration elucidate association between tissue miRNAs plasma. Aortic blood specimens were obtained from 38 patients: 12 controls 26 ascending aneurysm. Of BAV, 19 had cusp fusions right left, 5 non‑coronary, 2 left...
OBJECTIVE To present the long‐term outcome of patients with locally advanced or metastatic prostate carcinoma treated by first‐line antiandrogen monotherapy. PATIENTS AND METHODS From 1983 to 1990, 41 were flutamide monotherapy until progression appearance toxicity. Twenty‐five (61%) had T3‐T4N0M0 and 16 (39%) T2–4N0–3M1 carcinoma. Consensus criteria adopted evaluate response. Plasma testosterone sexual function recorded for first 3 years. RESULTS Flutamide was administered up 147 months;...
Abdominal entry is the critical initial step of laparoscopic surgery as it associated with unexpected complications. Acceptable working space a prerequisite for safe minimal access surgery. Direct trocar insertion (DTI) technique has been often reported to be time-consuming and capable causing injuries. We aim facilitate conventional DTI employing an easy-to-use self-designed abdominal wall-lifting device, OneShot-M. tested its safety in porcine model. 18 pigs were randomized into three...
The traditional cultural method (PCR and Real-Time PCR) for Salmonella spp. detection identification is laborious time-consuming. A qualitative LAMP detecting was validated in compliance with ISO 16140:2016. results show a relative accuracy, sensitivity, specificity of 100% comparison the reference 6579-1:2017; LOD50 set as 0.4 CFU/g. Additionally, field study carried out comparing kit, commercially available PCR kit (FoodProof Salmonella, Biotecon Diagnostics), method. suitable reliable...
<i>Introduction:</i> To evaluate whether percent free prostate-specific antigen (%-fPSA) could be predictive of pathological stage and Gleason score in patients with prostate cancer (PCa) serum PSA 10 ng/ml or less. <i>Materials Methods:</i> In 100 total PSA≤10 who underwent radical retropubic prostatectomy as primary treatment PCa, %-fPSA levels organ-confined vs. non-organ-confined PCa ≤/>7 were compared. <i>Results:</i> 32 had an 68 a locally...