A5071309662- Lipid Membrane Structure and Behavior
- Electrostatics and Colloid Interactions
- Force Microscopy Techniques and Applications
- Erythrocyte Function and Pathophysiology
- Cellular Mechanics and Interactions
- Nanopore and Nanochannel Transport Studies
- Cellular transport and secretion
- Microfluidic and Bio-sensing Technologies
- Extracellular vesicles in disease
- Bone Tissue Engineering Materials
- Spectroscopy and Quantum Chemical Studies
- Surfactants and Colloidal Systems
- Orthopaedic implants and arthroplasty
- Hip disorders and treatments
- Liquid Crystal Research Advancements
- Advanced Materials and Mechanics
- Blood properties and coagulation
- Microtubule and mitosis dynamics
- Total Knee Arthroplasty Outcomes
- Advanced Nanomaterials in Catalysis
- Geophysical and Geoelectrical Methods
- Micro and Nano Robotics
- RNA Interference and Gene Delivery
- Nanoplatforms for cancer theranostics
- Electrospun Nanofibers in Biomedical Applications
University of Ljubljana
2016-2025
Institute of Biosciences and Bioresources
2019-2021
National Research Council
2019-2021
Institute of Biophysics
1994-2019
Faculty (United Kingdom)
2015-2019
Jožef Stefan Institute
2007-2017
North Dakota State University
2008
University of Maribor
2007
Jožef Stefan International Postgraduate School
2007
Elektro Ljubljana (Slovenia)
2006
Abstract Cellular, inter‐organismal and cross kingdom communication via extracellular vesicles (EVs) is intensively studied in basic science with high expectation for a large variety of bio‐technological applications. EVs intrinsically possess many attributes drug delivery vehicle. Beyond the implications cell biology, academic industrial interests have increased last few years. Microalgae constitute sustainable renewable sources bioactive compounds range sectoral applications, including...
Biophysical and biochemical characterisation of microalgae-derived extracellular vesicles.
Anodic titanium dioxide (TiO2) nanostructures, i.e., obtained by electrochemical anodization, have excellent control over the nanoscale morphology and been extensively investigated in biomedical applications owing to their sub-100 nm topography range beneficial effects on biocompatibility cell interactions. Herein, we obtain TiO2 nanopores (NPs) nanotubes (NTs) with similar morphologies, namely, 15 diameter 500 length, investigate characteristics impact stem adhesion. We show that transition...
Peri-implantitis and peri-mucositis pose a severe threat to the success of dental implants. Current research focuses on development surfaces that inhibit biofilm formation while not inferring with tissue integration. This study compared adherence two oral bacterial species, Streptococcus sanguinis mutans nanostructured titanium surfaces.The samples included TiO2 nanotubes formed by anodization foil 100, 50 15nm diameter (NT15, NT50, NT100), nanoporous (15nm pore diameter) surface compact...
Titanium (Ti) is one of the most promising biomaterial for biomedical devices due to its high corrosion resistance and specific combination strength biocompatibility. dioxide (TiO2) nanostructures are obtained by electrochemical anodization Ti foils under self-organization condition; parameters such as time, voltage, temperature important electrolyte composition critical resulting morphology. Nanostructures grown in ethylene glycol (EG) based electrolytes we evaluated influence water...
Abstract: Titanium and titanium alloys are considered to be one of the most applicable materials in medical devices because their suitable properties, importantly high corrosion resistance specific combination strength with biocompatibility. In order improve biocompatibility surfaces, current report initially focuses on specifying topography dioxide (TiO2) nanotubes (NTs) by electrochemical anodization. The zeta potential (ζ-potential) NTs showed a negative value confirmed agreement between...
Migratory cells use distinct motility modes to navigate different microenvironments, but it is unclear whether these rely on the same core set of polarity components. To investigate this, we disrupted actin-related protein 2/3 (Arp2/3) and WASP-family verprolin homologous (WAVE) complex, which assemble branched actin networks that are essential for neutrophil in standard adherent conditions. Surprisingly, confinement rescues movement neutrophils lacking components, revealing a processive...
Eukaryote cells have a flexible shape, which dynamically changes according to the function performed by cell. One mechanism for deforming cell membrane into desired shape is through expression of curved proteins. Furthermore, these proteins are often associated with recruitment cytoskeleton, then applies active forces that deform membrane. This coupling between curvature and activity was previously explored theoretically in linear limit small deformations, low dimensionality. Here we explore...
Materials with controllable multifunctional abilities for optical imaging (OI) and magnetic resonant (MRI) that also can be used in photodynamic therapy are very interesting future applications. Mesoporous TiO2 sub-micrometer particles doped gadolinium to improve photoluminescence functionality spin relaxation MRI, the added benefit of enhanced generation reactive oxygen species (ROS). The Gd-doped exhibits red emission at 637 nm is beneficial OI significantly improves MRI times, a decrease...
Cells often migrate on curved surfaces inside the body, such as tissues, blood vessels or highly protrusions of other cells. Recent \textit{in-vitro} experiments provide clear evidence that motile cells are affected by curvature substrate which they migrate, preferring certain curvatures to others, termed ``curvotaxis". The origin and underlying mechanism gives rise this sensitivity not well understood. Here, we employ a ``minimal cell" model is composed vesicle contains membrane protein...
The distribution of raft markers in curved membrane exvaginations and invaginations, induced human erythrocytes by amphiphile-treatment or increased cytosolic calcium level, was studied fluorescence microscopy. Cholera toxin subunit B antibodies were used to detect components. Ganglioside GM1 enriched (spiculae) amphiphiles. Stomatin the proteins synexin sorcin spiculae when calcium, but not No enrichment flotillin-1 detected spiculae. Analyses relative protein content released exovesicles...