A5077268812- Birth, Development, and Health
- Adipose Tissue and Metabolism
- Liver physiology and pathology
- Organ Transplantation Techniques and Outcomes
- Growth Hormone and Insulin-like Growth Factors
- Cardiovascular Function and Risk Factors
- Liver Disease Diagnosis and Treatment
- Congenital heart defects research
- Diet and metabolism studies
- Diabetes Management and Research
- Geochemistry and Geologic Mapping
- Blood Pressure and Hypertension Studies
- Hematopoietic Stem Cell Transplantation
- Radioactive element chemistry and processing
- Radiopharmaceutical Chemistry and Applications
- Cellular Mechanics and Interactions
- Brain Metastases and Treatment
- Muscle Physiology and Disorders
- Metabolism, Diabetes, and Cancer
- Mesenchymal stem cell research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Liver Disease and Transplantation
- Vitamin D Research Studies
- Cardiovascular Health and Disease Prevention
- Cardiovascular Disease and Adiposity
Universidade do Estado do Rio de Janeiro
2012-2025
Pontifícia Universidade Católica do Rio Grande do Sul
2018-2024
University of Antofagasta
2024
Instituto do Câncer do Estado de São Paulo
2018
AC Camargo Hospital
2018
Centro de Pesquisas Oncológicas
2018
Instituto Brasileiro de Controle do Câncer
2018
Hospital de Clínicas de Porto Alegre
2018
Cultura
2013
Liver fibrosis results from chronic injury followed by activation of macrophages and fibrogenic cells like myofibroblasts activated hepatic stellate cells. These express α-smooth muscle actin (α-SMA) produce excessive extracellular matrix (ECM), with disorganization loss function parenchyma. It is known that increased levels metalloproteinases (MMPs) in liver are associated reduction the pathologic ECM resolution. Recently, it has been shown bone marrow mononuclear (BMMNCs) may reduce...
Introduction: Maternal obesity has been positively correlated with an increased cardiometabolic risk in the offspring throughout life, implying intergenerational transmission. However, little is known about early life cardiac cell modifications that imply onset of heart diseases later life. This study analyzed progenitor cells and cardiomyocyte differentiation on day birth born to obese dams. Methods: The litter size reduction model was used induce female Swiss mice. Both maternal groups,...
Liver fibrosis is accompanied by hepatocyte death and proliferation of α-SMA(+) fibrogenic cells (activated hepatic stellate myofibroblasts), which synthesize extracellular matrix components that contribute to disorganization the parenchyma loss liver function. Therefore, apoptosis these important regeneration. This study aimed analyze effect cell therapy using bone marrow mononuclear (BMMNC) transplantation on α-SMA expression during induced bile duct ligation (BDL). Livers were collected...
The use of reference materials (RMs) and certified (CRMs) is essential to guarantee the reliability measurement procedures ‐ a major factor motivating efforts geoanalytical community. This work quantifies trends patterns in scientific literature concerning RMs CRMs geochemistry for specific timespans, with aim evaluating historical developments, research fields, geographic shifts centres, current trends. Scopus database was surveyed peer‐reviewed full‐texts (14,201 documents), which were...
This study seeks to evaluate Insulin-like Growth Factor 1 (IGF-1) short-period therapy in Non-Alcoholic Fatty Liver Disease (NAFLD) as it relates western diet-induced obesity. For this purpose, 21-day-old male Swiss mice were divided into a control group (CG, N=8), which was fed standard diet, and an obese (GO, N=16), rich saturated fat simple carbohydrates, for 12 weeks. In the 11th week, part of animals (N=8) received daily subcutaneous injection recombinant human IGF-1 (100µg/kg/day)...
Abstract Background The incidence of brain metastases among women with metastatic breast cancer (MBC) ranges from 10 to 30% depending (BC) subtype. Inequities in the access optimal treatment and shorter survival BC by type health care coverage were previously reported an observational study Brazil. present analysis aims analyze impact on outcomes patients MBC involvement. Methods LACOG-0312 is a retrospective cohort that enrolled or locally advanced/recurrent unresectable diagnosed during...