Orly Weinstein

ORCID: 0000-0002-7913-513X
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Ocular Diseases and Behçet’s Syndrome
  • COVID-19 Clinical Research Studies
  • Autoimmune Bullous Skin Diseases
  • Retinal Imaging and Analysis
  • Dermatology and Skin Diseases
  • Glaucoma and retinal disorders
  • Urticaria and Related Conditions
  • COVID-19 and Mental Health
  • Retinal and Optic Conditions
  • Autism Spectrum Disorder Research
  • Vaccine Coverage and Hesitancy
  • Psoriasis: Treatment and Pathogenesis
  • Long-Term Effects of COVID-19
  • Ocular Infections and Treatments
  • Ocular Surface and Contact Lens
  • melanin and skin pigmentation
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Infectious Diseases and Tuberculosis
  • Virology and Viral Diseases
  • Diversity and Career in Medicine
  • Healthcare Systems and Reforms
  • Patient Satisfaction in Healthcare
  • Biochemical Analysis and Sensing Techniques

Clalit Health Services
2021-2025

Ben-Gurion University of the Negev
2006-2025

Bar-Ilan University
2021

Soroka Medical Center
1998-2020

Israel Ministry of Health
2017-2019

Israel Defense Forces Medical Corps
2004-2018

University Medical Center
2010

University Hospital and Clinics
2010

Individuals with schizophrenia may be at an increased risk for COVID-19 morbidity due to the disease characteristics. In this study, we aimed explore odds of significant and mortality among patients while controlling potential sociodemographic medical confounders.Schizophrenia age-and-sex matched controls (total n = 51 078) were assessed frequency positivity, hospitalizations, mortality. The COVID-19-associated hospitalization calculated using logistic regression models, age, sex, marital...

10.1093/schbul/sbab012 article EN other-oa Schizophrenia Bulletin 2021-01-26

Individuals with schizophrenia have an increased risk of severe COVID-19 outcomes, nonetheless, no previous study has provided a year-long account this risk, or assessed postvaccination trends in population. This temporal hospitalisation and mortality among people during the first year pandemic, predictors for vaccination, infection, admission to hospital, mortality.In longitudinal cohort study, (n=25 539) controls were outcomes before after up April 30, 2021. Cox proportional hazard...

10.1016/s2215-0366(21)00256-x article EN other-oa The Lancet Psychiatry 2021-08-06

Vaccination, especially with multiple doses, provides substantial population-level protection against COVID-19, but emerging variants of concern (VOC) and waning immunity represent significant risks at the individual level. Here we identify correlates (COP) in a multicenter prospective study following 607 healthy individuals who received three doses Pfizer-BNT162b2 vaccine approximately six months prior to enrollment. We compared 242 fourth dose 365 did not. Within 90 days enrollment, 239...

10.1038/s41467-023-39816-4 article EN cc-by Nature Communications 2023-07-29

Background & Objectives: To explore the potential association between positive ANA serology and all-cause mortality in a large cohort of patients, including those with without rheumatological conditions other immune-related diseases. Material Methods: A retrospective study analyzed among 205,862 patients from Clalit Health Services (CHS), Israel’s largest health maintenance organization (HMO). We compared aged 18 older (n = 102,931) to an equal number ANA-negative controls 102,931)....

10.3390/medicina61010060 article EN cc-by Medicina 2025-01-02

The risk of the infection and its complications under this drug class remains to be determined.To evaluate COVID-19, COVID-19-associated hospitalization, mortality among patients with psoriasis treated by IL-17I.A population-based cohort study was performed compare IL-17I (n = 680) those methotrexate 2153) non-systemic/non-immunomodulatory treatments 138,750) regarding incidence COVID-19 complications.The use not associated an increased [adjusted HR for vs. methotrexate: 0.91 (95% CI,...

10.1080/09546634.2021.1905766 article EN Journal of Dermatological Treatment 2021-03-24

Regulatory bodies are struggling to determine effective ways regulate artificial intelligence (AI)-driven health care solutions, which repeatedly exhibit suboptimal performance and unexpected outcomes when used in new settings. Existing evaluation frameworks typically structured as textual discussions that difficult translate into practical assessments of AI solutions often fail consider the perspectives specific populations data a designated deployment setting. Health organizations, faced...

10.1056/aics2300269 article EN NEJM AI 2024-08-14

Abstract The risk of coronavirus disease (COVID-19) infection and its complications among patients with atopic dermatitis (AD) treated by dupilumab is yet to be determined. We aimed assess the SARS-CoV-2 infection, COVID-19-associated hospitalization, mortality AD dupilumab. A population-based cohort study was conducted compare ( n = 238) those prolonged systemic corticosteroids (≥ 3 months; 1,023), phototherapy 461), azathioprine or mycophenolate mofetil (MMF; 194) regarding incidence...

10.1007/s12026-021-09234-z article EN cc-by Immunologic Research 2021-10-13

Individuals with schizophrenia are at higher risk for severe COVID-19 illness and mortality. Previous reports have demonstrated vaccination gaps among this high-risk population; however, it is unclear whether these continued to manifest the booster dose.To assess in first, second, vaccinations individuals schizophrenia.This was a matched, controlled, retrospective cohort study conducted November 2021, included follow-up data from March 2020, 2021. The used databases of Clalit Health...

10.1001/jamapsychiatry.2022.0382 article EN JAMA Psychiatry 2022-03-30

The burden of COVID-19 in patients with bullous pemphigoid (BP) and pemphigus is yet to be evaluated.To assess the risks COVID-19-associated hospitalization mortality BP delineate determinants severe illness among these patients.A population-based cohort study compared its complications (n = 1845) 1236) age-, sex-, ethnicity-matched control subjects.The (hazard rate [HR], 1.12; 95% confidence interval [CI], 0.72-1.73; P .691) (HR, 1.58; CI, 0.84-2.98; .160) was comparable between controls....

10.1016/j.jaad.2021.02.087 article EN other-oa Journal of the American Academy of Dermatology 2021-03-18

In this study we aimed to assess whether individuals with ASD are prone higher infection rates, or severe COVID-19 illness. Individuals and age- gender-matched controlled counterparts (total n = 32,812) were assessed for rates hospitalizations. Results indicated among ASD, the largest effect aged 40–60 (OR 2.05, 95%CI 1.33–3.15, p < .001), as well odds hospitalizations, evident primarily in men 2.40, 1.14–5.02, 0.02) but not women. Medical environmental risk factors may associate morbidity...

10.1007/s10803-021-05187-2 article EN other-oa Journal of Autism and Developmental Disorders 2021-07-08

Although bullous pemphigoid (BP), atopic dermatitis (AD), and allergic rhinitis (AR) are associated with shared pathogenic mechanisms the epidemiological relationship between these conditions remains to be investigated.To evaluate bidirectional association of BP AD AR.A population-based retrospective cohort study was performed comparing patients (n = 3924) age-, sex-, ethnicity-matched control subjects 19,280), respect incident cases AR. A case-control design additionally adopted assess odds...

10.1097/der.0000000000000792 article EN Dermatitis 2021-09-27

The timing pattern in which dipeptidyl-peptidase IV inhibitors (DPP4i) confer the risk of bullous pemphigoid (BP) is unknown. To investigate odds BP following exposure to DPP4i and perform a duration-response analysis evaluating relation duration culprit drug. A population-based nested case-control study was performed comparing diabetic patients with (n = 1458) age-, sex- ethnicity-matched control subjects 6051) respect prevalence DPP4i. Adjusted ratios (ORs) were estimated by logistic...

10.1007/s00403-021-02317-9 article EN cc-by Archives of Dermatological Research 2022-01-15

The impact of immune-related conditions on the outcomes coronavirus disease 2019 (COVID-19) is poorly understood. Determinants COVID-19 among patients with psoriasis are yet to be established.Th objective this study was characterize a large cohort and identify predictors COVID-19-associated hospitalization mortality.A population-based nested case-control performed using computerized database Clalit Health Services, Israel. Multivariable logistic regression used estimate odds ratios (ORs) 95%...

10.1007/s40257-021-00605-8 article EN cc-by-nc American Journal of Clinical Dermatology 2021-05-31

Our knowledge about the association between vitiligo and Parkinson's disease (PD) is sparse. We sought to investigate bidirectional epidemiological PD.

10.3389/fneur.2024.1387404 article EN cc-by Frontiers in Neurology 2024-05-21
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