A5069896469- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Viral-associated cancers and disorders
- Polyomavirus and related diseases
- Systemic Lupus Erythematosus Research
- Immune Cell Function and Interaction
- Lymphoma Diagnosis and Treatment
- Parvovirus B19 Infection Studies
- T-cell and Retrovirus Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Full-Duplex Wireless Communications
- Iron Metabolism and Disorders
- Herpesvirus Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Trace Elements in Health
- Antenna Design and Analysis
- Histiocytic Disorders and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Vector-Borne Animal Diseases
- Chronic Lymphocytic Leukemia Research
- Sarcoma Diagnosis and Treatment
- Animal Disease Management and Epidemiology
- Plant Virus Research Studies
Osaka Gakuin University
1998-2024
Tottori University
2014-2023
University College London
2023
Meijo Hospital
2018-2023
The London College
2023
Okayama University
1997-2022
Nagoya University
2010-2019
Fujita Health University
2001-2017
Ogaki Municipal Hospital
1999-2017
Nagasaki University
2017
The aim of this study was to determine whether antiviral therapy with lamivudine is beneficial in patients after initial treatment for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC).Forty-nine consecutive HBV-related HCC completely treated by hepatic resection or radiofrequency ablation were retrospectively enrolled study. Comparison made between 16 who received at a dose 100 mg/day (lamivudine group) and 33 did not (control terms changes remnant liver function, recurrence...
Hepatocellular carcinoma develops even in some patients who achieve a sustained virological response following treatment for hepatitis C virus infection. This study investigated the relationship between changes fibrosis, as assessed by sequential biopsies, and development of hepatocellular achieved virus.We enrolled 97 with had undergone initial biopsies before therapy at an average 5.8 ± 1.9 years after biopsy. Factors associated were retrospectively analyzed.The liver fibrotic stage...
The so-called very low density lipoprotein receptors (VLDLRs) are related to the LDLR gene family. So far, naturally occurring mutations have only been described for prototype LDLR; in humans, they cause familial hypercholesterolemia. Here we describe a mutation VLDLR that causes dramatic abnormal phenotype. Hens of mutant restricted-ovulator chicken strain carry single mutation, lack functional oocyte receptors, sterile, and display severe hyperlipidemia with associated premature...
Lens culinaris agglutinin-reactive fraction of alpha-fetoprotein (AFP-L3%) is a recently described marker hepatocellular carcinoma (HCC), and its usefulness has been demonstrated in many studies. We evaluated the serial measurement AFP-L3% as prognosis recurrence after treatment small HCC.AFP-L3% was measured before initial 60 patients with HCC (maximum diameter < or = 2 cm). taken ratio AFP-L3 to total AFP multiplied by 100%, levels > 10% were considered positive. Outcomes compared between...
Abstract Coding regions of the rbcL and matK genes cpDNA were sequenced to analyze phylogenetic relationships family Liliaceae sensu stricto , including major 16 genera Medeoloideae Lilioideae Liliaceae, in reference several such as Scoliopus, Uvularia, Disporum Trillium used outgoups. The results congruent with taxonomic concept recently proposed by Tamura (1998) . inter‐ infrageneric genus Lilium allied taxa then analyzed based upon gene sequencing data, using Medeola Erythronium...
Various undifferentiated embryonic stem (ES) cells can grow on mouse fibroblast (MEF) feeders. However, the risk of zoonosis from animal feeders to human ES generally excludes clinical use these cells. We have found that placenta is a useful source feeder for growth primate As MEF feeders, cultured amniotic epithelial (HAE) and chorionic plate (HCP) had growth. The expressed Oct‐4, alkaline phosphatase, SSEA‐4. HAE produced typical immature teratomas in vivo after injection into severe...
The aim of this study was to evaluate the efficacy and indication combination therapy with ribavirin plus peginterferon-alpha-2b in chronic hepatitis C virus (HCV) patients aged 65 years older.Five hundred ninety-one consecutive HCV were treated therapy. These divided into elder (> or = years) (n=115) younger (< (n=476). clinical characteristics, sustained virological response (SVR) rates discontinuation compared between two groups.Compared patients, baseline haemoglobin levels platelet...
Background/Aim: (–)-Epigallocatechin-3-gallate (EGCG) has been indicated to regulate the function of P-glycoprotein (P-gp), which is a drug transporter encoded by MDR1 (ABCB1) gene. P-gp expression induced doxorubicin (DOX). We aimed clarify mechanisms and inhibitory effects EGCG on DOX-induced in HepG2 cells. Materials Methods: Rhodamine 123 (Rho123) was used for substrate. Western blotting polymerase chain reactions (PCRs) were conducted using specific antibodies primer sets. Results: The...
Abstract Background and Aim Severe muscle volume loss is a recognized negative prognostic factor in patients with chronic liver disease. However, the effect of skeletal fat deposition, referred to as myosteatosis on remains unclear. The aim this study was investigate relationships between loss. Methods We enrolled 362 disease (186 men, 176 women; mean age 68.4 ± 10.0 years, 94 cirrhosis) who underwent biopsy computed tomography scanning January 2013 February 2017. A transverse image each...
Acoustic radiation force impulse (ARFI) elastography is a non-invasive method for measuring liver stiffness. However, there are no reports evaluating the value of ARFI fibrosis in chronic hepatitis C patients with sustained virological response (SVR).To investigate diagnostic performance assessment virus (HCV) infected an SVR.In this prospective study, we enrolled 336 patients: 121 HCV SVR (44.6% women) and 215 (47.9% women). measurements all were performed on same day biopsy.The accuracies,...