A5065828661- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Pancreatic and Hepatic Oncology Research
- Liver Disease and Transplantation
- Pancreatitis Pathology and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Gallbladder and Bile Duct Disorders
- Systemic Lupus Erythematosus Research
- Liver Diseases and Immunity
- Organ Transplantation Techniques and Outcomes
- Gut microbiota and health
- Gastric Cancer Management and Outcomes
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Ultrasound Imaging and Elastography
- Inflammatory Bowel Disease
- Nutrition and Health in Aging
- Cancer Immunotherapy and Biomarkers
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal Tumor Research and Treatment
- Neuroendocrine Tumor Research Advances
- Diet, Metabolism, and Disease
- Drug-Induced Hepatotoxicity and Protection
Nagoya University
2016-2025
Nagoya City University
2009-2024
Second Affiliated Hospital of Xi'an Jiaotong University
2024
Kaohsiung Medical University
2024
National Sun Yat-sen University
2024
The University of Tokyo
2023
Kindai University
2023
Kinjo Gakuin University
2023
Nagoya University Hospital
2010-2020
GTx (United States)
2019
HCC risk in chronic hepatitis B (CHB) is higher the indeterminate phase compared with inactive phase. However, it unclear if antiviral therapy reduces this population. We aimed to evaluate association between and
There are limited data on antiviral treatment
In Brief Background and Aim: Intraductal papillary mucinous neoplasms (IPMNs) have a wide pathologic spectrum it is difficult to differentiate malignant from benign tumors. The aim of this study was identify predictors malignancy using contrast-enhanced endoscopic ultrasound (CE-EUS). Subjects Methods: our institute, main duct type mixed IPMNs, branch IPMNs with mural nodules, coexistent invasive ductal cancer were indications for surgery. Eighty-seven (14 duct, 25 mixed, 48 type) resected...
This study aimed to investigate the usefulness of contrast-enhanced endoscopic ultrasonography (EUS) with time-intensity curve (TIC) in differentiating pancreatic diseases.Patients who underwent EUS between January 2007 and June 2009 were analyzed retrospectively, including 48 ductal cancer (PC), 14 autoimmune pancreatitis (AIP), 13 mass-forming (MFP), 16 endocrine tumor (PET). After intravenous injection contrast agent, imaging pattern, TIC-based quantitative evaluation, diagnostic ability...
The aim of this study was to determine whether antiviral therapy with lamivudine is beneficial in patients after initial treatment for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC).Forty-nine consecutive HBV-related HCC completely treated by hepatic resection or radiofrequency ablation were retrospectively enrolled study. Comparison made between 16 who received at a dose 100 mg/day (lamivudine group) and 33 did not (control terms changes remnant liver function, recurrence...
The natural history of branch duct-type intraductal papillary mucinous neoplasms (BD-IPMNs) the pancreas remains unclear. We conducted a retrospective long-term follow-up study for malignant transformation (MT) BD-IPMNs focusing on morphological changes.The subjects consisted 142 patients who underwent contrast-enhanced endoscopic ultrasonography initial diagnosis from January 2001 with more than 12 months follow-up. MT rate, including co-occurrence invasive ductal cancer, was evaluated by...
Hepatocellular carcinoma develops even in some patients who achieve a sustained virological response following treatment for hepatitis C virus infection. This study investigated the relationship between changes fibrosis, as assessed by sequential biopsies, and development of hepatocellular achieved virus.We enrolled 97 with had undergone initial biopsies before therapy at an average 5.8 ± 1.9 years after biopsy. Factors associated were retrospectively analyzed.The liver fibrotic stage...
Abstract Chronic liver injury from various causes often results in fibrosis (LF). Although the possesses endogenous tissue-repairing activities, these can be overcome by sustained inflammation and excessive fibrotic scar formation. Advanced LF leads to irreversible cirrhosis subsequent failure and/or hepatic cancer. Here, using mouse carbon tetrachloride (CCl4)-induced model, we showed that a single intravenous administration of stem cells derived human exfoliated deciduous teeth (SHEDs) or...
Nonalcoholic steatohepatitis (NASH) is a hepatic phenotype of the metabolic syndrome, and increases risk cirrhosis hepatocellular carcinoma (HCC). Although increasing evidence points to therapeutic implications certain types anti-diabetic agents in NASH, it remains be elucidated whether their effects on NASH are independent diabetes. Genetically obese melanocortin 4 receptor-deficient (MC4R-KO) mice fed Western diet murine model that sequentially develops steatosis, HCC presence obesity...
Mucosal healing, confirmed by endoscopic evaluation, is the long-term goal of treatment for Crohn's disease (CD). Leucine-rich alpha-2 glycoprotein (LRG) a new serum biomarker correlated with activity in inflammatory bowel disease. However, studies evaluating its relationship CD, particularly context small intestinal lesions, are scarce. The aim this study was to investigate accuracy LRG assessing activity, especially remission, patients CD.Between July 2020 and March 2021, 72 CD who...
Summary Background Ulcerative colitis involves an excessive immune response to intestinal bacteria. Whether administering prebiotic 1‐kestose is effective for active ulcerative remains controversial. Aims This randomised, double‐blind, placebo‐controlled pilot trial investigated the efficacy of against colitis. Methods Forty patients with mild moderate were randomly treated ( N = 20) or placebo (maltose, orally 8 weeks in addition standard treatment. The Lichtiger clinical activity index and...
Summary Background Racial and ethnic disparities exist for hepatitis C virus (HCV) treatment hepatocellular carcinoma (HCC) survival. Aim To evaluate the impact of HCV on such disparities. Methods In a retrospective cohort study, we analysed 6069 patients with HCV‐related HCC (54.2% Asian, 30.1% White, 8.5% Black, 7.3% Hispanic) from centres in United States Asia. Results The mean age was 61, 60, 59 68, respectively, Hispanic Asian patients. Black were most likely to have Barcelona Clinic...