- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Body Contouring and Surgery
- Cardiovascular Disease and Adiposity
- Obesity and Health Practices
- Enhanced Recovery After Surgery
- Gallbladder and Bile Duct Disorders
- Adipose Tissue and Metabolism
- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Cardiac, Anesthesia and Surgical Outcomes
- Nutrition and Health in Aging
- Minimally Invasive Surgical Techniques
- Esophageal Cancer Research and Treatment
- Diabetes Treatment and Management
- Adipokines, Inflammation, and Metabolic Diseases
- Diverse academic and cultural studies
- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Dysphagia Assessment and Management
- Parathyroid Disorders and Treatments
Rush University Medical Center
2016-2024
John Wiley & Sons (United States)
2019
Rush University
2019
Hudson Institute
2019
New York Academy of Sciences
2019
Albert Einstein College of Medicine
2019
Montefiore Medical Center
2019
Duke University
2008-2017
Duke University Hospital
2010-2016
Duke Medical Center
2009-2016
We sought to determine the impact of addition Dor fundoplication on incidence postoperative gastroesophageal reflux (GER) after Heller myotomy.Based only case series, many surgeons believe that an antireflux procedure should be added myotomy. However, no prospective randomized data support this approach.In prospective, randomized, double-blind, institutional review board-approved clinical trial, patients with achalasia were assigned undergo myotomy or plus fundoplication. Patients studied...
In Brief Objective: Laparoscopic myotomy is the preferred treatment of achalasia. Our objectives were to assess long-term outcome esophageal and identify preoperative factors influencing outcome. Methods: Preoperative data collected from patients undergoing laparoscopic for achalasia at our institution. The primary endpoint study was postoperative change (delta) in dysphagia score. This score calculated by combining frequency severity dysphagia. Persistent defined as 1 standard deviation...
This study investigates the rates of obesity-related cancers in patients undergoing vertical sleeve gastrectomy (VSG), Roux-en-Y gastric bypass (RYGB), or no surgical intervention.Obesity has been previously associated with increased cancers; however, weight loss surgeries have not explored to demonstrate their potential risk reduction impact.Patients meeting bariatric eligibility criteria between January 2010 and December 2018 were identified. Exact 1:1:1 matching based on baseline patient...
Objectives: The aim of the study was to compare long-term outcomes 2 groups morbidly obese patients with type diabetes mellitus—1 managed by Roux-en-Y gastric bypass surgery and a comparable group medically. Methods: present single-institution retrospective study. Of 173 mellitus undergoing between January 2000 July 2004, 78 (45%) were followed for at least 10 years. control consisted 80 diabetic from same period similar body mass index, age, race, severity diabetes. median follow-up 11...
Given the complex relationship between body mass index, composition, and bone density correlative nature of studies that have established prevailing notion higher indices may be protective against osteopenia osteoporosis and, therefore, fracture, absolute risk fracture in patients with severe obesity who undergo either Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) compared those do not bariatric surgery is unknown.To assess rates fractures associated compare surgery, RYGB, SG.In...
Objective To compare the short-term results of radiofrequency treatment gastroesophageal junction known as Stretta procedure versus laparoscopic fundoplication (LF) in patients with reflux disease (GERD). Summary Background Data The has been shown to be safe, well tolerated, and highly effective GERD. Methods All presenting Vanderbilt University Medical Center for surgical evaluation GERD between August 2000 March 2002 were prospectively evaluated under an IRB-approved protocol. underwent...
Roux-en-Y gastric bypass (RYGB) surgery results in exaggerated postprandial insulin and incretin responses increased susceptibility to hypoglycemia.We examined whether these features are due caloric restriction (CR) or altered nutrient handling.We performed comprehensive analysis of metabolite during a 2-hour mixed-meal tolerance (MMT) test 20 morbidly obese subjects with type 2 diabetes who underwent RYGB matched CR. Acylcarnitines amino acids (AAs) were measured using targeted mass...
Choline metabolism is important for very low-density lipoprotein secretion, making this nutritional pathway an contributor to hepatic lipid balance. The purpose of study was assess whether the cumulative effects multiple single nucleotide polymorphisms (SNPs) across genes choline/1-carbon and functionally related pathways increase susceptibility developing steatosis. In biopsy-characterized cases nonalcoholic fatty liver disease controls, we assessed 260 SNPs 21 in metabolism. When were...
Obesity surgery is becoming one of the most common general procedures done in United States. Internal hernias are a known and increasingly more occurrence after laparoscopic roux-en-Y gastric bypass (LRYGB). Increased clinical awareness this complication will lead to decreased surgical morbidity mortality. We retrospectively reviewed our database 529 patients who had undergone LRYGB from 2000 2005 identified those presenting with intestinal obstruction an internal hernia. The type hernia...